| Full name: WAP four-disulfide core domain 1 | Alias Symbol: PS20 | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 58189 | HGNC ID: HGNC:15466 | Ensembl Gene: ENSG00000103175 | OMIM ID: 605322 |
| Drug and gene relationship at DGIdb | |||
Expression of WFDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WFDC1 | 58189 | 219478_at | -0.9010 | 0.2370 | |
| GSE20347 | WFDC1 | 58189 | 219478_at | -0.5420 | 0.0589 | |
| GSE23400 | WFDC1 | 58189 | 219478_at | -1.0380 | 0.0000 | |
| GSE26886 | WFDC1 | 58189 | 219478_at | 0.2273 | 0.2689 | |
| GSE29001 | WFDC1 | 58189 | 219478_at | -0.6700 | 0.0086 | |
| GSE38129 | WFDC1 | 58189 | 219478_at | -1.3117 | 0.0004 | |
| GSE45670 | WFDC1 | 58189 | 219478_at | -1.4868 | 0.0004 | |
| GSE53622 | WFDC1 | 58189 | 100237 | -1.6583 | 0.0000 | |
| GSE53624 | WFDC1 | 58189 | 100237 | -2.0029 | 0.0000 | |
| GSE63941 | WFDC1 | 58189 | 219478_at | -5.2250 | 0.0000 | |
| GSE77861 | WFDC1 | 58189 | 219478_at | 0.4241 | 0.0894 | |
| GSE97050 | WFDC1 | 58189 | A_23_P106617 | -0.6621 | 0.4153 | |
| SRP064894 | WFDC1 | 58189 | RNAseq | -1.9180 | 0.0000 | |
| SRP133303 | WFDC1 | 58189 | RNAseq | -1.4255 | 0.0000 | |
| SRP159526 | WFDC1 | 58189 | RNAseq | -1.6040 | 0.0002 | |
| TCGA | WFDC1 | 58189 | RNAseq | -1.0067 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by WFDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WFDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WFDC1 | 58189 | 4 | 4 | 22 | |
| GSE20123 | WFDC1 | 58189 | 4 | 4 | 22 | |
| GSE43470 | WFDC1 | 58189 | 2 | 10 | 31 | |
| GSE46452 | WFDC1 | 58189 | 37 | 2 | 20 | |
| GSE47630 | WFDC1 | 58189 | 11 | 9 | 20 | |
| GSE54993 | WFDC1 | 58189 | 3 | 4 | 63 | |
| GSE54994 | WFDC1 | 58189 | 8 | 10 | 35 | |
| GSE60625 | WFDC1 | 58189 | 4 | 0 | 7 | |
| GSE74703 | WFDC1 | 58189 | 2 | 7 | 27 | |
| GSE74704 | WFDC1 | 58189 | 3 | 2 | 15 | |
| TCGA | WFDC1 | 58189 | 26 | 16 | 54 |
Total number of gains: 104; Total number of losses: 68; Total Number of normals: 316.
Somatic mutations of WFDC1:
Generating mutation plots.
Highly correlated genes for WFDC1:
Showing top 20/938 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WFDC1 | RCAN2 | 0.821756 | 12 | 0 | 12 |
| WFDC1 | IL13RA2 | 0.780258 | 3 | 0 | 3 |
| WFDC1 | ATOH8 | 0.777856 | 4 | 0 | 4 |
| WFDC1 | CLEC3B | 0.768066 | 3 | 0 | 3 |
| WFDC1 | CYP21A2 | 0.755652 | 3 | 0 | 3 |
| WFDC1 | FOXF1 | 0.752123 | 13 | 0 | 12 |
| WFDC1 | ZBTB4 | 0.748133 | 4 | 0 | 4 |
| WFDC1 | ARHGAP6 | 0.747821 | 10 | 0 | 10 |
| WFDC1 | C1orf198 | 0.74157 | 4 | 0 | 4 |
| WFDC1 | LINC01082 | 0.739574 | 6 | 0 | 5 |
| WFDC1 | TCF21 | 0.738688 | 11 | 0 | 11 |
| WFDC1 | RSPO2 | 0.738324 | 3 | 0 | 3 |
| WFDC1 | MRVI1 | 0.736958 | 8 | 0 | 8 |
| WFDC1 | CNRIP1 | 0.734554 | 8 | 0 | 7 |
| WFDC1 | RASL12 | 0.732336 | 10 | 0 | 10 |
| WFDC1 | KLHL30 | 0.730071 | 3 | 0 | 3 |
| WFDC1 | ITIH5 | 0.729662 | 11 | 0 | 11 |
| WFDC1 | BHMT2 | 0.729564 | 10 | 0 | 10 |
| WFDC1 | C3orf70 | 0.729145 | 7 | 0 | 6 |
| WFDC1 | ZNF583 | 0.72903 | 3 | 0 | 3 |
For details and further investigation, click here
