| Full name: F-box protein 7 | Alias Symbol: FBX7|Fbx|PARK15 | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 25793 | HGNC ID: HGNC:13586 | Ensembl Gene: ENSG00000100225 | OMIM ID: 605648 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FBXO7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO7 | 25793 | 1554423_a_at | -0.0136 | 0.9779 | |
| GSE20347 | FBXO7 | 25793 | 201178_at | 0.1492 | 0.2262 | |
| GSE23400 | FBXO7 | 25793 | 201178_at | 0.1643 | 0.0018 | |
| GSE26886 | FBXO7 | 25793 | 201178_at | 0.3562 | 0.0241 | |
| GSE29001 | FBXO7 | 25793 | 201178_at | 0.1610 | 0.5525 | |
| GSE38129 | FBXO7 | 25793 | 201178_at | 0.0553 | 0.5516 | |
| GSE45670 | FBXO7 | 25793 | 201178_at | 0.0709 | 0.6290 | |
| GSE53622 | FBXO7 | 25793 | 112723 | 0.1412 | 0.0129 | |
| GSE53624 | FBXO7 | 25793 | 112723 | 0.2339 | 0.0000 | |
| GSE63941 | FBXO7 | 25793 | 1554423_a_at | 0.8557 | 0.0139 | |
| GSE77861 | FBXO7 | 25793 | 201178_at | 0.4016 | 0.0528 | |
| GSE97050 | FBXO7 | 25793 | A_23_P29225 | -0.0343 | 0.8731 | |
| SRP007169 | FBXO7 | 25793 | RNAseq | -0.0117 | 0.9685 | |
| SRP008496 | FBXO7 | 25793 | RNAseq | 0.1329 | 0.6003 | |
| SRP064894 | FBXO7 | 25793 | RNAseq | 0.2579 | 0.0955 | |
| SRP133303 | FBXO7 | 25793 | RNAseq | 0.0729 | 0.6147 | |
| SRP159526 | FBXO7 | 25793 | RNAseq | 0.2570 | 0.0904 | |
| SRP193095 | FBXO7 | 25793 | RNAseq | -0.0837 | 0.3865 | |
| SRP219564 | FBXO7 | 25793 | RNAseq | 0.3553 | 0.1693 | |
| TCGA | FBXO7 | 25793 | RNAseq | -0.0562 | 0.1992 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBXO7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO7 | 25793 | 4 | 5 | 21 | |
| GSE20123 | FBXO7 | 25793 | 4 | 4 | 22 | |
| GSE43470 | FBXO7 | 25793 | 5 | 5 | 33 | |
| GSE46452 | FBXO7 | 25793 | 31 | 1 | 27 | |
| GSE47630 | FBXO7 | 25793 | 8 | 5 | 27 | |
| GSE54993 | FBXO7 | 25793 | 3 | 6 | 61 | |
| GSE54994 | FBXO7 | 25793 | 9 | 10 | 34 | |
| GSE60625 | FBXO7 | 25793 | 5 | 0 | 6 | |
| GSE74703 | FBXO7 | 25793 | 4 | 5 | 27 | |
| GSE74704 | FBXO7 | 25793 | 1 | 1 | 18 | |
| TCGA | FBXO7 | 25793 | 27 | 15 | 54 |
Total number of gains: 101; Total number of losses: 57; Total Number of normals: 330.
Somatic mutations of FBXO7:
Generating mutation plots.
Highly correlated genes for FBXO7:
Showing top 20/492 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO7 | IRF2BPL | 0.746679 | 3 | 0 | 3 |
| FBXO7 | TTC30B | 0.744641 | 4 | 0 | 4 |
| FBXO7 | C1orf198 | 0.731143 | 3 | 0 | 3 |
| FBXO7 | KANSL3 | 0.725359 | 4 | 0 | 4 |
| FBXO7 | PTPMT1 | 0.703137 | 3 | 0 | 3 |
| FBXO7 | EFTUD2 | 0.702709 | 4 | 0 | 4 |
| FBXO7 | HES4 | 0.694729 | 3 | 0 | 3 |
| FBXO7 | USP21 | 0.684676 | 4 | 0 | 4 |
| FBXO7 | CORO1C | 0.683737 | 4 | 0 | 4 |
| FBXO7 | PSMC4 | 0.677257 | 4 | 0 | 3 |
| FBXO7 | KLHDC3 | 0.674838 | 3 | 0 | 3 |
| FBXO7 | ILVBL | 0.674322 | 3 | 0 | 3 |
| FBXO7 | UNG | 0.670909 | 3 | 0 | 3 |
| FBXO7 | STAT5B | 0.664935 | 4 | 0 | 3 |
| FBXO7 | ZNF280C | 0.662635 | 4 | 0 | 4 |
| FBXO7 | ZNF766 | 0.662088 | 4 | 0 | 3 |
| FBXO7 | TUFM | 0.661221 | 3 | 0 | 3 |
| FBXO7 | GHDC | 0.65184 | 4 | 0 | 3 |
| FBXO7 | TSEN15 | 0.650572 | 4 | 0 | 3 |
| FBXO7 | MRPL47 | 0.64782 | 3 | 0 | 3 |
For details and further investigation, click here
