| Full name: chromosome 1 open reading frame 21 | Alias Symbol: PIG13 | ||
| Type: protein-coding gene | Cytoband: 1q25.3 | ||
| Entrez ID: 81563 | HGNC ID: HGNC:15494 | Ensembl Gene: ENSG00000116667 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C1orf21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf21 | 81563 | 223125_s_at | -0.2172 | 0.7228 | |
| GSE20347 | C1orf21 | 81563 | 221272_s_at | -0.2752 | 0.0013 | |
| GSE23400 | C1orf21 | 81563 | 221272_s_at | -0.2435 | 0.0000 | |
| GSE26886 | C1orf21 | 81563 | 223125_s_at | -1.6728 | 0.0000 | |
| GSE29001 | C1orf21 | 81563 | 221272_s_at | -0.3644 | 0.2704 | |
| GSE38129 | C1orf21 | 81563 | 221272_s_at | -0.7508 | 0.0001 | |
| GSE45670 | C1orf21 | 81563 | 223125_s_at | -0.4965 | 0.0099 | |
| GSE53622 | C1orf21 | 81563 | 104349 | -0.9667 | 0.0000 | |
| GSE53624 | C1orf21 | 81563 | 104349 | -0.8582 | 0.0000 | |
| GSE63941 | C1orf21 | 81563 | 223125_s_at | -1.4122 | 0.1135 | |
| GSE77861 | C1orf21 | 81563 | 223125_s_at | -0.9200 | 0.0485 | |
| GSE97050 | C1orf21 | 81563 | A_24_P173754 | -1.0959 | 0.0502 | |
| SRP007169 | C1orf21 | 81563 | RNAseq | -1.8271 | 0.0013 | |
| SRP008496 | C1orf21 | 81563 | RNAseq | -1.1398 | 0.0039 | |
| SRP064894 | C1orf21 | 81563 | RNAseq | -0.6031 | 0.0066 | |
| SRP133303 | C1orf21 | 81563 | RNAseq | -1.0902 | 0.0000 | |
| SRP159526 | C1orf21 | 81563 | RNAseq | -1.0319 | 0.0001 | |
| SRP193095 | C1orf21 | 81563 | RNAseq | -0.9262 | 0.0000 | |
| SRP219564 | C1orf21 | 81563 | RNAseq | -0.1214 | 0.7408 | |
| TCGA | C1orf21 | 81563 | RNAseq | -0.2654 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by C1orf21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf21 | 81563 | 12 | 0 | 18 | |
| GSE20123 | C1orf21 | 81563 | 12 | 0 | 18 | |
| GSE43470 | C1orf21 | 81563 | 7 | 1 | 35 | |
| GSE46452 | C1orf21 | 81563 | 3 | 1 | 55 | |
| GSE47630 | C1orf21 | 81563 | 14 | 0 | 26 | |
| GSE54993 | C1orf21 | 81563 | 0 | 6 | 64 | |
| GSE54994 | C1orf21 | 81563 | 15 | 0 | 38 | |
| GSE60625 | C1orf21 | 81563 | 0 | 0 | 11 | |
| GSE74703 | C1orf21 | 81563 | 7 | 1 | 28 | |
| GSE74704 | C1orf21 | 81563 | 5 | 0 | 15 | |
| TCGA | C1orf21 | 81563 | 40 | 3 | 53 |
Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.
Somatic mutations of C1orf21:
Generating mutation plots.
Highly correlated genes for C1orf21:
Showing top 20/1230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf21 | NDUFV3 | 0.75881 | 3 | 0 | 3 |
| C1orf21 | ALKBH8 | 0.751562 | 3 | 0 | 3 |
| C1orf21 | PIGP | 0.730312 | 3 | 0 | 3 |
| C1orf21 | HOXA4 | 0.728599 | 7 | 0 | 7 |
| C1orf21 | CCDC112 | 0.720495 | 3 | 0 | 3 |
| C1orf21 | MPP7 | 0.713423 | 6 | 0 | 5 |
| C1orf21 | KIF5C | 0.712605 | 3 | 0 | 3 |
| C1orf21 | JMJD1C | 0.711863 | 3 | 0 | 3 |
| C1orf21 | ZNF585A | 0.711516 | 4 | 0 | 4 |
| C1orf21 | C2CD2 | 0.711186 | 3 | 0 | 3 |
| C1orf21 | TMOD1 | 0.711141 | 4 | 0 | 3 |
| C1orf21 | ANGPT1 | 0.709294 | 4 | 0 | 4 |
| C1orf21 | NKTR | 0.705569 | 3 | 0 | 3 |
| C1orf21 | PPP2R5E | 0.702678 | 3 | 0 | 3 |
| C1orf21 | NFIA | 0.702407 | 8 | 0 | 7 |
| C1orf21 | SBF2 | 0.701756 | 4 | 0 | 3 |
| C1orf21 | ANO8 | 0.700597 | 3 | 0 | 3 |
| C1orf21 | KCNN3 | 0.697131 | 3 | 0 | 3 |
| C1orf21 | CPEB4 | 0.694773 | 5 | 0 | 5 |
| C1orf21 | EEA1 | 0.693746 | 6 | 0 | 6 |
For details and further investigation, click here
