| Full name: chromosome 1 open reading frame 52 | Alias Symbol: gm117|FLJ44982 | ||
| Type: protein-coding gene | Cytoband: 1p22.3 | ||
| Entrez ID: 148423 | HGNC ID: HGNC:24871 | Ensembl Gene: ENSG00000162642 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C1orf52:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf52 | 148423 | 228135_at | 0.2827 | 0.3089 | |
| GSE26886 | C1orf52 | 148423 | 228135_at | 0.4827 | 0.0209 | |
| GSE45670 | C1orf52 | 148423 | 228135_at | 0.1746 | 0.1621 | |
| GSE53622 | C1orf52 | 148423 | 19234 | 0.3298 | 0.0000 | |
| GSE53624 | C1orf52 | 148423 | 19234 | 0.4165 | 0.0000 | |
| GSE63941 | C1orf52 | 148423 | 228135_at | -0.1467 | 0.7052 | |
| GSE77861 | C1orf52 | 148423 | 228135_at | -0.0059 | 0.9824 | |
| GSE97050 | C1orf52 | 148423 | A_33_P3300273 | -0.0722 | 0.7905 | |
| SRP007169 | C1orf52 | 148423 | RNAseq | 1.0175 | 0.0588 | |
| SRP008496 | C1orf52 | 148423 | RNAseq | 1.0286 | 0.0165 | |
| SRP064894 | C1orf52 | 148423 | RNAseq | 0.0744 | 0.5660 | |
| SRP133303 | C1orf52 | 148423 | RNAseq | 0.2570 | 0.0366 | |
| SRP159526 | C1orf52 | 148423 | RNAseq | -0.3469 | 0.2579 | |
| SRP193095 | C1orf52 | 148423 | RNAseq | 0.0955 | 0.2718 | |
| SRP219564 | C1orf52 | 148423 | RNAseq | -0.1859 | 0.6214 | |
| TCGA | C1orf52 | 148423 | RNAseq | 0.0053 | 0.9277 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by C1orf52 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf52:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf52 | 148423 | 0 | 8 | 22 | |
| GSE20123 | C1orf52 | 148423 | 0 | 8 | 22 | |
| GSE43470 | C1orf52 | 148423 | 2 | 2 | 39 | |
| GSE46452 | C1orf52 | 148423 | 0 | 1 | 58 | |
| GSE47630 | C1orf52 | 148423 | 8 | 5 | 27 | |
| GSE54993 | C1orf52 | 148423 | 0 | 0 | 70 | |
| GSE54994 | C1orf52 | 148423 | 6 | 3 | 44 | |
| GSE60625 | C1orf52 | 148423 | 0 | 0 | 11 | |
| GSE74703 | C1orf52 | 148423 | 1 | 2 | 33 | |
| GSE74704 | C1orf52 | 148423 | 0 | 5 | 15 | |
| TCGA | C1orf52 | 148423 | 7 | 23 | 66 |
Total number of gains: 24; Total number of losses: 57; Total Number of normals: 407.
Somatic mutations of C1orf52:
Generating mutation plots.
Highly correlated genes for C1orf52:
Showing top 20/65 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf52 | HNRNPDL | 0.643623 | 3 | 0 | 3 |
| C1orf52 | ZNF593 | 0.634453 | 3 | 0 | 3 |
| C1orf52 | HIVEP2 | 0.626901 | 4 | 0 | 3 |
| C1orf52 | HSPBAP1 | 0.610654 | 4 | 0 | 3 |
| C1orf52 | JRKL | 0.598837 | 3 | 0 | 3 |
| C1orf52 | SRP19 | 0.589666 | 3 | 0 | 3 |
| C1orf52 | SCUBE1 | 0.585055 | 3 | 0 | 3 |
| C1orf52 | EMC1 | 0.581318 | 7 | 0 | 6 |
| C1orf52 | OTUD4 | 0.581114 | 4 | 0 | 3 |
| C1orf52 | STK32C | 0.579478 | 3 | 0 | 3 |
| C1orf52 | USB1 | 0.577818 | 5 | 0 | 3 |
| C1orf52 | BNC1 | 0.57728 | 4 | 0 | 3 |
| C1orf52 | TAF1D | 0.57678 | 5 | 0 | 4 |
| C1orf52 | HOMER1 | 0.576708 | 5 | 0 | 3 |
| C1orf52 | LAMC2 | 0.57472 | 6 | 0 | 5 |
| C1orf52 | ASB6 | 0.571999 | 4 | 0 | 3 |
| C1orf52 | PDCD11 | 0.569148 | 4 | 0 | 3 |
| C1orf52 | OSMR | 0.56763 | 4 | 0 | 4 |
| C1orf52 | GPR158 | 0.566773 | 5 | 0 | 3 |
| C1orf52 | MLF1 | 0.565388 | 4 | 0 | 3 |
For details and further investigation, click here
