| Full name: HSPB1 associated protein 1 | Alias Symbol: FLJ22623|PASS1 | ||
| Type: protein-coding gene | Cytoband: 3q21.1 | ||
| Entrez ID: 79663 | HGNC ID: HGNC:16389 | Ensembl Gene: ENSG00000169087 | OMIM ID: 608263 |
| Drug and gene relationship at DGIdb | |||
Expression of HSPBAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSPBAP1 | 79663 | 219284_at | 1.0079 | 0.0194 | |
| GSE20347 | HSPBAP1 | 79663 | 219284_at | 1.2570 | 0.0000 | |
| GSE23400 | HSPBAP1 | 79663 | 219284_at | 0.7376 | 0.0000 | |
| GSE26886 | HSPBAP1 | 79663 | 219284_at | 2.0916 | 0.0000 | |
| GSE29001 | HSPBAP1 | 79663 | 219284_at | 1.0260 | 0.0169 | |
| GSE38129 | HSPBAP1 | 79663 | 219284_at | 1.0786 | 0.0000 | |
| GSE45670 | HSPBAP1 | 79663 | 219284_at | 0.6004 | 0.0126 | |
| GSE53622 | HSPBAP1 | 79663 | 95323 | 0.7668 | 0.0000 | |
| GSE53624 | HSPBAP1 | 79663 | 95323 | 0.8413 | 0.0000 | |
| GSE63941 | HSPBAP1 | 79663 | 219284_at | -0.0784 | 0.9177 | |
| GSE77861 | HSPBAP1 | 79663 | 219284_at | 0.9567 | 0.0525 | |
| GSE97050 | HSPBAP1 | 79663 | A_33_P3331120 | 0.2121 | 0.5114 | |
| SRP007169 | HSPBAP1 | 79663 | RNAseq | 1.0150 | 0.0324 | |
| SRP008496 | HSPBAP1 | 79663 | RNAseq | 1.4427 | 0.0003 | |
| SRP064894 | HSPBAP1 | 79663 | RNAseq | 0.9516 | 0.0000 | |
| SRP133303 | HSPBAP1 | 79663 | RNAseq | 0.5977 | 0.0039 | |
| SRP159526 | HSPBAP1 | 79663 | RNAseq | 0.8077 | 0.0065 | |
| SRP193095 | HSPBAP1 | 79663 | RNAseq | 0.7920 | 0.0000 | |
| SRP219564 | HSPBAP1 | 79663 | RNAseq | 0.6472 | 0.0490 | |
| TCGA | HSPBAP1 | 79663 | RNAseq | 0.3572 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by HSPBAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSPBAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSPBAP1 | 79663 | 18 | 0 | 12 | |
| GSE20123 | HSPBAP1 | 79663 | 18 | 0 | 12 | |
| GSE43470 | HSPBAP1 | 79663 | 20 | 0 | 23 | |
| GSE46452 | HSPBAP1 | 79663 | 14 | 5 | 40 | |
| GSE47630 | HSPBAP1 | 79663 | 17 | 4 | 19 | |
| GSE54993 | HSPBAP1 | 79663 | 2 | 6 | 62 | |
| GSE54994 | HSPBAP1 | 79663 | 30 | 4 | 19 | |
| GSE60625 | HSPBAP1 | 79663 | 0 | 6 | 5 | |
| GSE74703 | HSPBAP1 | 79663 | 16 | 0 | 20 | |
| GSE74704 | HSPBAP1 | 79663 | 13 | 0 | 7 | |
| TCGA | HSPBAP1 | 79663 | 54 | 6 | 36 |
Total number of gains: 202; Total number of losses: 31; Total Number of normals: 255.
Somatic mutations of HSPBAP1:
Generating mutation plots.
Highly correlated genes for HSPBAP1:
Showing top 20/519 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSPBAP1 | RASGEF1A | 0.785663 | 3 | 0 | 3 |
| HSPBAP1 | TNFAIP8L1 | 0.733149 | 5 | 0 | 5 |
| HSPBAP1 | DCPS | 0.733148 | 3 | 0 | 3 |
| HSPBAP1 | PTPRH | 0.724373 | 3 | 0 | 3 |
| HSPBAP1 | BMP8B | 0.722198 | 4 | 0 | 3 |
| HSPBAP1 | IQCB1 | 0.717082 | 11 | 0 | 10 |
| HSPBAP1 | POLR3A | 0.716109 | 3 | 0 | 3 |
| HSPBAP1 | RFC4 | 0.712816 | 10 | 0 | 10 |
| HSPBAP1 | TMEM102 | 0.709686 | 3 | 0 | 3 |
| HSPBAP1 | AP1S1 | 0.706517 | 4 | 0 | 4 |
| HSPBAP1 | NPW | 0.70537 | 4 | 0 | 3 |
| HSPBAP1 | ARHGAP22 | 0.70368 | 3 | 0 | 3 |
| HSPBAP1 | CBX3 | 0.702788 | 11 | 0 | 11 |
| HSPBAP1 | FBXO44 | 0.69915 | 3 | 0 | 3 |
| HSPBAP1 | GPRIN1 | 0.69779 | 5 | 0 | 5 |
| HSPBAP1 | MLF1 | 0.693197 | 11 | 0 | 11 |
| HSPBAP1 | DUSP9 | 0.692526 | 5 | 0 | 3 |
| HSPBAP1 | PIK3R4 | 0.692368 | 12 | 0 | 10 |
| HSPBAP1 | RAD54B | 0.68794 | 9 | 0 | 8 |
| HSPBAP1 | KIF26B | 0.687551 | 6 | 0 | 6 |
For details and further investigation, click here
