| Full name: chromosome 1 open reading frame 53 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q31.3 | ||
| Entrez ID: 388722 | HGNC ID: HGNC:30003 | Ensembl Gene: ENSG00000203724 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C1orf53:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf53 | 388722 | 1558508_a_at | 1.1988 | 0.1189 | |
| GSE26886 | C1orf53 | 388722 | 1558508_a_at | 0.9318 | 0.0361 | |
| GSE45670 | C1orf53 | 388722 | 1558508_a_at | 0.6951 | 0.0112 | |
| GSE53622 | C1orf53 | 388722 | 36143 | 0.4018 | 0.0060 | |
| GSE53624 | C1orf53 | 388722 | 36143 | 0.5762 | 0.0000 | |
| GSE63941 | C1orf53 | 388722 | 1558508_a_at | 0.0109 | 0.9918 | |
| GSE77861 | C1orf53 | 388722 | 1558507_at | -0.0194 | 0.9128 | |
| GSE97050 | C1orf53 | 388722 | A_32_P210572 | -0.1321 | 0.7928 | |
| SRP133303 | C1orf53 | 388722 | RNAseq | 0.4571 | 0.1630 | |
| SRP159526 | C1orf53 | 388722 | RNAseq | 0.6527 | 0.0896 | |
| SRP219564 | C1orf53 | 388722 | RNAseq | 1.4662 | 0.0169 | |
| TCGA | C1orf53 | 388722 | RNAseq | 0.4365 | 0.0238 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by C1orf53 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf53:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf53 | 388722 | 6 | 0 | 24 | |
| GSE20123 | C1orf53 | 388722 | 6 | 0 | 24 | |
| GSE43470 | C1orf53 | 388722 | 7 | 0 | 36 | |
| GSE46452 | C1orf53 | 388722 | 3 | 1 | 55 | |
| GSE47630 | C1orf53 | 388722 | 14 | 0 | 26 | |
| GSE54993 | C1orf53 | 388722 | 0 | 6 | 64 | |
| GSE54994 | C1orf53 | 388722 | 16 | 0 | 37 | |
| GSE60625 | C1orf53 | 388722 | 0 | 0 | 11 | |
| GSE74703 | C1orf53 | 388722 | 7 | 0 | 29 | |
| GSE74704 | C1orf53 | 388722 | 1 | 0 | 19 | |
| TCGA | C1orf53 | 388722 | 41 | 6 | 49 |
Total number of gains: 101; Total number of losses: 13; Total Number of normals: 374.
Somatic mutations of C1orf53:
Generating mutation plots.
Highly correlated genes for C1orf53:
Showing top 20/139 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf53 | ASCL2 | 0.743606 | 3 | 0 | 3 |
| C1orf53 | OPA3 | 0.703622 | 3 | 0 | 3 |
| C1orf53 | NEB | 0.692299 | 3 | 0 | 3 |
| C1orf53 | TRIM9 | 0.678881 | 3 | 0 | 3 |
| C1orf53 | TLK1 | 0.65158 | 4 | 0 | 3 |
| C1orf53 | FDPS | 0.626943 | 4 | 0 | 3 |
| C1orf53 | C14orf119 | 0.609076 | 4 | 0 | 4 |
| C1orf53 | CAMSAP2 | 0.608289 | 3 | 0 | 3 |
| C1orf53 | BRMS1 | 0.605939 | 4 | 0 | 4 |
| C1orf53 | RNF217 | 0.605496 | 4 | 0 | 3 |
| C1orf53 | FASTKD1 | 0.603776 | 4 | 0 | 3 |
| C1orf53 | ATXN3 | 0.602751 | 3 | 0 | 3 |
| C1orf53 | ZNF107 | 0.601993 | 4 | 0 | 3 |
| C1orf53 | MTCL1 | 0.601615 | 3 | 0 | 3 |
| C1orf53 | RFC3 | 0.597271 | 4 | 0 | 3 |
| C1orf53 | FARSA | 0.59419 | 4 | 0 | 4 |
| C1orf53 | RBM8A | 0.589158 | 4 | 0 | 3 |
| C1orf53 | EFCAB11 | 0.588953 | 5 | 0 | 4 |
| C1orf53 | ISCA2 | 0.586012 | 7 | 0 | 6 |
| C1orf53 | BYSL | 0.585614 | 5 | 0 | 5 |
For details and further investigation, click here
