| Full name: nebulin | Alias Symbol: NEB177D | ||
| Type: protein-coding gene | Cytoband: 2q23.3 | ||
| Entrez ID: 4703 | HGNC ID: HGNC:7720 | Ensembl Gene: ENSG00000183091 | OMIM ID: 161650 |
| Drug and gene relationship at DGIdb | |||
Expression of NEB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEB | 4703 | 205054_at | 1.9971 | 0.0599 | |
| GSE20347 | NEB | 4703 | 205054_at | 0.7612 | 0.0015 | |
| GSE23400 | NEB | 4703 | 205054_at | 0.5294 | 0.0003 | |
| GSE26886 | NEB | 4703 | 205054_at | 1.9261 | 0.0003 | |
| GSE29001 | NEB | 4703 | 215368_at | 0.0395 | 0.7296 | |
| GSE38129 | NEB | 4703 | 205054_at | 0.9416 | 0.0000 | |
| GSE45670 | NEB | 4703 | 205054_at | 1.7656 | 0.0003 | |
| GSE53622 | NEB | 4703 | 41953 | 1.4953 | 0.0000 | |
| GSE53624 | NEB | 4703 | 41953 | 1.3241 | 0.0000 | |
| GSE63941 | NEB | 4703 | 205054_at | 0.6919 | 0.2711 | |
| GSE77861 | NEB | 4703 | 205054_at | 1.2184 | 0.0114 | |
| GSE97050 | NEB | 4703 | A_33_P3214844 | -1.3562 | 0.3387 | |
| SRP007169 | NEB | 4703 | RNAseq | 2.6260 | 0.0002 | |
| SRP133303 | NEB | 4703 | RNAseq | 2.2037 | 0.0000 | |
| SRP159526 | NEB | 4703 | RNAseq | 2.4985 | 0.0000 | |
| SRP193095 | NEB | 4703 | RNAseq | 1.7614 | 0.0000 | |
| SRP219564 | NEB | 4703 | RNAseq | 1.3319 | 0.0294 | |
| TCGA | NEB | 4703 | RNAseq | 1.4488 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by NEB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEB | 4703 | 3 | 2 | 25 | |
| GSE20123 | NEB | 4703 | 3 | 2 | 25 | |
| GSE43470 | NEB | 4703 | 3 | 1 | 39 | |
| GSE46452 | NEB | 4703 | 1 | 4 | 54 | |
| GSE47630 | NEB | 4703 | 5 | 3 | 32 | |
| GSE54993 | NEB | 4703 | 0 | 5 | 65 | |
| GSE54994 | NEB | 4703 | 11 | 2 | 40 | |
| GSE60625 | NEB | 4703 | 0 | 3 | 8 | |
| GSE74703 | NEB | 4703 | 2 | 1 | 33 | |
| GSE74704 | NEB | 4703 | 2 | 0 | 18 | |
| TCGA | NEB | 4703 | 21 | 9 | 66 |
Total number of gains: 51; Total number of losses: 32; Total Number of normals: 405.
Somatic mutations of NEB:
Generating mutation plots.
Highly correlated genes for NEB:
Showing top 20/502 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEB | PTPN4 | 0.737755 | 4 | 0 | 4 |
| NEB | RASEF | 0.705633 | 5 | 0 | 5 |
| NEB | DNAJC30 | 0.702797 | 3 | 0 | 3 |
| NEB | SMYD4 | 0.699353 | 4 | 0 | 4 |
| NEB | GPR107 | 0.696859 | 3 | 0 | 3 |
| NEB | HDAC2 | 0.693867 | 3 | 0 | 3 |
| NEB | C1orf53 | 0.692299 | 3 | 0 | 3 |
| NEB | HOXC9 | 0.690998 | 4 | 0 | 4 |
| NEB | QSOX2 | 0.69072 | 4 | 0 | 4 |
| NEB | ATF5 | 0.687876 | 3 | 0 | 3 |
| NEB | IGSF9 | 0.687044 | 5 | 0 | 4 |
| NEB | MBD4 | 0.681024 | 5 | 0 | 4 |
| NEB | WDR81 | 0.680739 | 4 | 0 | 4 |
| NEB | MRPL50 | 0.679069 | 3 | 0 | 3 |
| NEB | EMC6 | 0.668631 | 3 | 0 | 3 |
| NEB | DHX33 | 0.66109 | 4 | 0 | 4 |
| NEB | TBP | 0.655538 | 4 | 0 | 3 |
| NEB | HOXD13 | 0.655397 | 6 | 0 | 4 |
| NEB | RAPGEF4 | 0.651453 | 4 | 0 | 3 |
| NEB | CASK | 0.651144 | 4 | 0 | 3 |
For details and further investigation, click here
