| Full name: EF-hand calcium binding domain 11 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.11 | ||
| Entrez ID: 90141 | HGNC ID: HGNC:20357 | Ensembl Gene: ENSG00000140025 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of EFCAB11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFCAB11 | 90141 | 214264_s_at | 0.3875 | 0.5431 | |
| GSE20347 | EFCAB11 | 90141 | 214264_s_at | -0.0466 | 0.8676 | |
| GSE23400 | EFCAB11 | 90141 | 214264_s_at | 0.2706 | 0.0001 | |
| GSE26886 | EFCAB11 | 90141 | 214264_s_at | 0.2590 | 0.3008 | |
| GSE29001 | EFCAB11 | 90141 | 214264_s_at | 0.1756 | 0.6499 | |
| GSE38129 | EFCAB11 | 90141 | 214264_s_at | 0.4042 | 0.0544 | |
| GSE45670 | EFCAB11 | 90141 | 214264_s_at | 0.5060 | 0.0203 | |
| GSE53622 | EFCAB11 | 90141 | 35187 | 0.3660 | 0.0000 | |
| GSE53624 | EFCAB11 | 90141 | 35187 | 0.4151 | 0.0000 | |
| GSE63941 | EFCAB11 | 90141 | 214264_s_at | 0.8621 | 0.1039 | |
| GSE77861 | EFCAB11 | 90141 | 214264_s_at | 0.2037 | 0.6507 | |
| GSE97050 | EFCAB11 | 90141 | A_23_P129014 | 0.1698 | 0.4691 | |
| SRP007169 | EFCAB11 | 90141 | RNAseq | 0.3317 | 0.4838 | |
| SRP008496 | EFCAB11 | 90141 | RNAseq | 0.1452 | 0.7298 | |
| SRP064894 | EFCAB11 | 90141 | RNAseq | 0.4319 | 0.0108 | |
| SRP133303 | EFCAB11 | 90141 | RNAseq | 0.3405 | 0.0086 | |
| SRP159526 | EFCAB11 | 90141 | RNAseq | 0.3604 | 0.2149 | |
| SRP193095 | EFCAB11 | 90141 | RNAseq | 0.0847 | 0.3245 | |
| SRP219564 | EFCAB11 | 90141 | RNAseq | 0.2231 | 0.5194 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EFCAB11 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of EFCAB11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFCAB11 | 90141 | 9 | 5 | 16 | |
| GSE20123 | EFCAB11 | 90141 | 9 | 5 | 16 | |
| GSE43470 | EFCAB11 | 90141 | 7 | 3 | 33 | |
| GSE46452 | EFCAB11 | 90141 | 16 | 3 | 40 | |
| GSE47630 | EFCAB11 | 90141 | 11 | 8 | 21 | |
| GSE54993 | EFCAB11 | 90141 | 3 | 8 | 59 | |
| GSE54994 | EFCAB11 | 90141 | 19 | 4 | 30 | |
| GSE60625 | EFCAB11 | 90141 | 0 | 2 | 9 | |
| GSE74703 | EFCAB11 | 90141 | 6 | 3 | 27 | |
| GSE74704 | EFCAB11 | 90141 | 4 | 4 | 12 | |
| TCGA | EFCAB11 | 90141 | 32 | 20 | 44 |
Total number of gains: 116; Total number of losses: 65; Total Number of normals: 307.
Somatic mutations of EFCAB11:
Generating mutation plots.
Highly correlated genes for EFCAB11:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFCAB11 | DYNC1LI1 | 0.625971 | 4 | 0 | 3 |
| EFCAB11 | PLSCR2 | 0.606431 | 3 | 0 | 3 |
| EFCAB11 | TRAIP | 0.605183 | 4 | 0 | 3 |
| EFCAB11 | ARL11 | 0.602849 | 3 | 0 | 3 |
| EFCAB11 | HIVEP2 | 0.598162 | 3 | 0 | 3 |
| EFCAB11 | PITPNA-AS1 | 0.596612 | 3 | 0 | 3 |
| EFCAB11 | GTF2H4 | 0.592764 | 6 | 0 | 4 |
| EFCAB11 | C1orf53 | 0.588953 | 5 | 0 | 4 |
| EFCAB11 | NKX2-8 | 0.582187 | 3 | 0 | 3 |
| EFCAB11 | LAMTOR2 | 0.578868 | 4 | 0 | 3 |
| EFCAB11 | CUTC | 0.574993 | 4 | 0 | 3 |
| EFCAB11 | PERP | 0.574082 | 3 | 0 | 3 |
| EFCAB11 | SUV39H2 | 0.572116 | 6 | 0 | 4 |
| EFCAB11 | UROD | 0.556672 | 5 | 0 | 4 |
| EFCAB11 | LRR1 | 0.5558 | 8 | 0 | 5 |
| EFCAB11 | RWDD3 | 0.555787 | 4 | 0 | 3 |
| EFCAB11 | EFNA4 | 0.555098 | 7 | 0 | 4 |
| EFCAB11 | TTLL5 | 0.554135 | 7 | 0 | 4 |
| EFCAB11 | POLE2 | 0.55193 | 11 | 0 | 6 |
| EFCAB11 | SEH1L | 0.550628 | 3 | 0 | 3 |
For details and further investigation, click here
