| Full name: mitochondrial pyruvate carrier 2 | Alias Symbol: DKFZP564B167|SLC54A2 | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 25874 | HGNC ID: HGNC:24515 | Ensembl Gene: ENSG00000143158 | OMIM ID: 614737 |
| Drug and gene relationship at DGIdb | |||
Expression of MPC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPC2 | 25874 | 202427_s_at | 0.3018 | 0.3872 | |
| GSE20347 | MPC2 | 25874 | 202427_s_at | 0.4140 | 0.0183 | |
| GSE23400 | MPC2 | 25874 | 202427_s_at | 0.3057 | 0.0003 | |
| GSE26886 | MPC2 | 25874 | 202427_s_at | 0.0711 | 0.7693 | |
| GSE29001 | MPC2 | 25874 | 202427_s_at | 0.2424 | 0.3295 | |
| GSE38129 | MPC2 | 25874 | 202427_s_at | 0.3491 | 0.0258 | |
| GSE45670 | MPC2 | 25874 | 202427_s_at | 0.2175 | 0.1014 | |
| GSE53622 | MPC2 | 25874 | 163635 | -0.3574 | 0.0000 | |
| GSE53624 | MPC2 | 25874 | 163635 | -0.1306 | 0.0248 | |
| GSE63941 | MPC2 | 25874 | 202427_s_at | -0.6120 | 0.0718 | |
| GSE77861 | MPC2 | 25874 | 202427_s_at | 0.2674 | 0.2172 | |
| SRP007169 | MPC2 | 25874 | RNAseq | -0.2973 | 0.4296 | |
| SRP008496 | MPC2 | 25874 | RNAseq | -0.0670 | 0.7979 | |
| SRP064894 | MPC2 | 25874 | RNAseq | -0.1386 | 0.5691 | |
| SRP133303 | MPC2 | 25874 | RNAseq | 0.3325 | 0.0044 | |
| SRP159526 | MPC2 | 25874 | RNAseq | 0.4771 | 0.1887 | |
| SRP193095 | MPC2 | 25874 | RNAseq | -0.1746 | 0.3381 | |
| SRP219564 | MPC2 | 25874 | RNAseq | -0.0821 | 0.8661 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MPC2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MPC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPC2 | 25874 | 11 | 1 | 18 | |
| GSE20123 | MPC2 | 25874 | 11 | 1 | 18 | |
| GSE43470 | MPC2 | 25874 | 7 | 2 | 34 | |
| GSE46452 | MPC2 | 25874 | 3 | 1 | 55 | |
| GSE47630 | MPC2 | 25874 | 14 | 0 | 26 | |
| GSE54993 | MPC2 | 25874 | 0 | 6 | 64 | |
| GSE54994 | MPC2 | 25874 | 16 | 0 | 37 | |
| GSE60625 | MPC2 | 25874 | 0 | 0 | 11 | |
| GSE74703 | MPC2 | 25874 | 7 | 2 | 27 | |
| GSE74704 | MPC2 | 25874 | 5 | 0 | 15 | |
| TCGA | MPC2 | 25874 | 44 | 3 | 49 |
Total number of gains: 118; Total number of losses: 16; Total Number of normals: 354.
Somatic mutations of MPC2:
Generating mutation plots.
Highly correlated genes for MPC2:
Showing top 20/172 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPC2 | RNF139 | 0.677064 | 3 | 0 | 3 |
| MPC2 | C1orf43 | 0.660456 | 4 | 0 | 3 |
| MPC2 | BCAP31 | 0.64514 | 3 | 0 | 3 |
| MPC2 | RAD51C | 0.634863 | 5 | 0 | 4 |
| MPC2 | C14orf93 | 0.634535 | 3 | 0 | 3 |
| MPC2 | MRPS14 | 0.630349 | 8 | 0 | 6 |
| MPC2 | ZNF496 | 0.623063 | 3 | 0 | 3 |
| MPC2 | NME7 | 0.605712 | 5 | 0 | 3 |
| MPC2 | TMEM14B | 0.601517 | 5 | 0 | 3 |
| MPC2 | HNRNPU | 0.600726 | 5 | 0 | 5 |
| MPC2 | DCAF6 | 0.59285 | 11 | 0 | 9 |
| MPC2 | DUSP12 | 0.59281 | 7 | 0 | 5 |
| MPC2 | UHMK1 | 0.590213 | 4 | 0 | 3 |
| MPC2 | PTPRJ | 0.590036 | 5 | 0 | 3 |
| MPC2 | VMA21 | 0.583216 | 3 | 0 | 3 |
| MPC2 | CHST12 | 0.582274 | 4 | 0 | 4 |
| MPC2 | CERS2 | 0.579378 | 8 | 0 | 7 |
| MPC2 | TRMT5 | 0.575612 | 5 | 0 | 3 |
| MPC2 | NRIP3 | 0.57365 | 4 | 0 | 4 |
| MPC2 | LAMC1 | 0.572678 | 6 | 0 | 6 |
For details and further investigation, click here
