| Full name: ubiquitin like modifier activating enzyme 1 | Alias Symbol: UBE1X|POC20|CFAP124 | ||
| Type: protein-coding gene | Cytoband: Xp11.3 | ||
| Entrez ID: 7317 | HGNC ID: HGNC:12469 | Ensembl Gene: ENSG00000130985 | OMIM ID: 314370 |
| Drug and gene relationship at DGIdb | |||
Expression of UBA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBA1 | 7317 | 200964_at | 0.2677 | 0.5336 | |
| GSE20347 | UBA1 | 7317 | 200964_at | -0.5588 | 0.0013 | |
| GSE23400 | UBA1 | 7317 | 200964_at | -0.1493 | 0.0802 | |
| GSE26886 | UBA1 | 7317 | 200964_at | -0.2456 | 0.5485 | |
| GSE29001 | UBA1 | 7317 | 200964_at | -0.4462 | 0.2441 | |
| GSE38129 | UBA1 | 7317 | 200964_at | -0.2579 | 0.1211 | |
| GSE45670 | UBA1 | 7317 | 200964_at | 0.3843 | 0.0819 | |
| GSE53622 | UBA1 | 7317 | 1407 | -0.2129 | 0.0019 | |
| GSE53624 | UBA1 | 7317 | 1407 | -0.2184 | 0.0000 | |
| GSE63941 | UBA1 | 7317 | 200964_at | 1.8045 | 0.0017 | |
| GSE77861 | UBA1 | 7317 | 200964_at | -0.1210 | 0.6780 | |
| GSE97050 | UBA1 | 7317 | A_23_P137209 | 0.1417 | 0.6233 | |
| SRP007169 | UBA1 | 7317 | RNAseq | -1.1399 | 0.0005 | |
| SRP008496 | UBA1 | 7317 | RNAseq | -1.2215 | 0.0000 | |
| SRP064894 | UBA1 | 7317 | RNAseq | -0.0220 | 0.8892 | |
| SRP133303 | UBA1 | 7317 | RNAseq | 0.0419 | 0.8450 | |
| SRP159526 | UBA1 | 7317 | RNAseq | 0.1780 | 0.6027 | |
| SRP193095 | UBA1 | 7317 | RNAseq | -0.1689 | 0.1225 | |
| SRP219564 | UBA1 | 7317 | RNAseq | -0.0302 | 0.8841 | |
| TCGA | UBA1 | 7317 | RNAseq | 0.0352 | 0.3593 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by UBA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBA1:
No record found for this gene.
Somatic mutations of UBA1:
Generating mutation plots.
Highly correlated genes for UBA1:
Showing top 20/474 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBA1 | PRKCSH | 0.798766 | 4 | 0 | 4 |
| UBA1 | SKP2 | 0.772316 | 3 | 0 | 3 |
| UBA1 | TMEM41A | 0.749544 | 3 | 0 | 3 |
| UBA1 | ZFPL1 | 0.744835 | 4 | 0 | 4 |
| UBA1 | APOO | 0.741005 | 4 | 0 | 4 |
| UBA1 | SPSB2 | 0.736424 | 3 | 0 | 3 |
| UBA1 | TAF10 | 0.734977 | 3 | 0 | 3 |
| UBA1 | RASAL3 | 0.722961 | 3 | 0 | 3 |
| UBA1 | CDC42EP1 | 0.72089 | 4 | 0 | 4 |
| UBA1 | TYSND1 | 0.715207 | 3 | 0 | 3 |
| UBA1 | SELPLG | 0.713613 | 3 | 0 | 3 |
| UBA1 | TPM3 | 0.710974 | 3 | 0 | 3 |
| UBA1 | GPR160 | 0.706398 | 3 | 0 | 3 |
| UBA1 | STIP1 | 0.70596 | 3 | 0 | 3 |
| UBA1 | MAP3K13 | 0.70563 | 3 | 0 | 3 |
| UBA1 | SLC1A5 | 0.700137 | 3 | 0 | 3 |
| UBA1 | PHLDB1 | 0.697156 | 3 | 0 | 3 |
| UBA1 | CHID1 | 0.694298 | 3 | 0 | 3 |
| UBA1 | NR2C2AP | 0.691287 | 4 | 0 | 3 |
| UBA1 | ALDH5A1 | 0.691039 | 3 | 0 | 3 |
For details and further investigation, click here
