KIFC1

 

Full name: kinesin family member C1 Alias Symbol: HSET
Type: protein-coding gene Cytoband: 6p21.32
Entrez ID: 3833 HGNC ID: HGNC:6389 Ensembl Gene: ENSG00000237649 OMIM ID: 603763
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of KIFC1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KIFC1 3833 209680_s_at 0.9308 0.0616
GSE20347 KIFC1 3833 209680_s_at 0.4467 0.0000
GSE23400 KIFC1 3833 209680_s_at 0.5137 0.0000
GSE26886 KIFC1 3833 209680_s_at 0.2189 0.1928
GSE29001 KIFC1 3833 209680_s_at 0.5449 0.0141
GSE38129 KIFC1 3833 209680_s_at 0.6433 0.0000
GSE45670 KIFC1 3833 209680_s_at 0.6689 0.0021
GSE53622 KIFC1 3833 109920 1.2529 0.0000
GSE53624 KIFC1 3833 109920 1.3304 0.0000
GSE63941 KIFC1 3833 209680_s_at 2.2451 0.0001
GSE77861 KIFC1 3833 209680_s_at 0.2905 0.0542
GSE97050 KIFC1 3833 A_23_P133956 1.5280 0.1399
SRP007169 KIFC1 3833 RNAseq 2.3245 0.0004
SRP064894 KIFC1 3833 RNAseq 1.6533 0.0000
SRP133303 KIFC1 3833 RNAseq 1.0618 0.0000
SRP159526 KIFC1 3833 RNAseq 1.4011 0.0001
SRP193095 KIFC1 3833 RNAseq 0.8941 0.0000
SRP219564 KIFC1 3833 RNAseq 1.2872 0.0761
TCGA KIFC1 3833 RNAseq 1.2404 0.0000

Upregulated datasets: 8; Downregulated datasets: 0.  

 

Survival by KIFC1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KIFC1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KIFC1 3833 5 0 25
GSE20123 KIFC1 3833 5 0 25
GSE43470 KIFC1 3833 4 1 38
GSE46452 KIFC1 3833 2 9 48
GSE47630 KIFC1 3833 8 4 28
GSE54993 KIFC1 3833 3 1 66
GSE54994 KIFC1 3833 11 4 38
GSE60625 KIFC1 3833 1 0 10
GSE74703 KIFC1 3833 4 0 32
GSE74704 KIFC1 3833 2 0 18
TCGA KIFC1 3833 15 16 65

Total number of gains: 60; Total number of losses: 35; Total Number of normals: 393.  

 

Somatic mutations of KIFC1:

 

Generating mutation plots.

 

Highly correlated genes for KIFC1:

 

Showing top 20/1699 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KIFC1UCK20.793392303
KIFC1SKA30.791372707
KIFC1STARD100.790853303
KIFC1UBE2C0.78763613013
KIFC1TIMELESS0.78332112012
KIFC1MMS22L0.779654303
KIFC1SPC240.774415807
KIFC1KIF2C0.76824213012
KIFC1MYBL20.7676212012
KIFC1CENPF0.76755213012
KIFC1EXO10.76621810010
KIFC1MND10.765922707
KIFC1NUF20.76325909
KIFC1NEK20.76316713011
KIFC1CDC450.7600312012
KIFC1DKC10.758349303
KIFC1UHRF10.75339909
KIFC1TROAP0.7528113012
KIFC1NUSAP10.75127513013
KIFC1HJURP0.75090613012

For details and further investigation, click here