| Full name: KH domain containing 3 like, subcortical maternal complex member | Alias Symbol: ECAT1 | ||
| Type: protein-coding gene | Cytoband: 6q13 | ||
| Entrez ID: 154288 | HGNC ID: HGNC:33699 | Ensembl Gene: ENSG00000203908 | OMIM ID: 611687 |
| Drug and gene relationship at DGIdb | |||
Expression of KHDC3L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KHDC3L | 154288 | 231474_at | -0.0296 | 0.9494 | |
| GSE26886 | KHDC3L | 154288 | 231474_at | 0.2724 | 0.0100 | |
| GSE45670 | KHDC3L | 154288 | 231474_at | 0.0647 | 0.6019 | |
| GSE53622 | KHDC3L | 154288 | 16814 | 0.0378 | 0.8469 | |
| GSE53624 | KHDC3L | 154288 | 16814 | 0.2515 | 0.0076 | |
| GSE63941 | KHDC3L | 154288 | 231474_at | 0.3343 | 0.0394 | |
| GSE77861 | KHDC3L | 154288 | 231474_at | -0.0298 | 0.8127 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KHDC3L expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of KHDC3L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KHDC3L | 154288 | 1 | 3 | 26 | |
| GSE20123 | KHDC3L | 154288 | 1 | 2 | 27 | |
| GSE43470 | KHDC3L | 154288 | 3 | 0 | 40 | |
| GSE46452 | KHDC3L | 154288 | 2 | 11 | 46 | |
| GSE47630 | KHDC3L | 154288 | 8 | 4 | 28 | |
| GSE54993 | KHDC3L | 154288 | 3 | 2 | 65 | |
| GSE54994 | KHDC3L | 154288 | 8 | 9 | 36 | |
| GSE60625 | KHDC3L | 154288 | 0 | 1 | 10 | |
| GSE74703 | KHDC3L | 154288 | 3 | 0 | 33 | |
| GSE74704 | KHDC3L | 154288 | 0 | 1 | 19 | |
| TCGA | KHDC3L | 154288 | 10 | 21 | 65 |
Total number of gains: 39; Total number of losses: 54; Total Number of normals: 395.
Somatic mutations of KHDC3L:
Generating mutation plots.
Highly correlated genes for KHDC3L:
Showing top 20/91 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KHDC3L | AIRE | 0.744349 | 3 | 0 | 3 |
| KHDC3L | MGAT5B | 0.687258 | 3 | 0 | 3 |
| KHDC3L | CRIP3 | 0.686411 | 3 | 0 | 3 |
| KHDC3L | C9orf116 | 0.665454 | 3 | 0 | 3 |
| KHDC3L | TLX1 | 0.665387 | 3 | 0 | 3 |
| KHDC3L | COPE | 0.662024 | 3 | 0 | 3 |
| KHDC3L | ITIH1 | 0.660976 | 3 | 0 | 3 |
| KHDC3L | NEBL-AS1 | 0.655083 | 3 | 0 | 3 |
| KHDC3L | CHRD | 0.64496 | 3 | 0 | 3 |
| KHDC3L | ASCL5 | 0.64286 | 3 | 0 | 3 |
| KHDC3L | IQCH | 0.640029 | 4 | 0 | 3 |
| KHDC3L | PERM1 | 0.637872 | 3 | 0 | 3 |
| KHDC3L | KLK2 | 0.634604 | 3 | 0 | 3 |
| KHDC3L | MIR146A | 0.633467 | 3 | 0 | 3 |
| KHDC3L | E2F4 | 0.632768 | 3 | 0 | 3 |
| KHDC3L | FABP2 | 0.632116 | 3 | 0 | 3 |
| KHDC3L | VCX2 | 0.631769 | 4 | 0 | 3 |
| KHDC3L | HDAC10 | 0.630282 | 3 | 0 | 3 |
| KHDC3L | SWI5 | 0.625793 | 3 | 0 | 3 |
| KHDC3L | LHX1 | 0.619437 | 4 | 0 | 3 |
For details and further investigation, click here
