| Full name: cyclin G2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 901 | HGNC ID: HGNC:1593 | Ensembl Gene: ENSG00000138764 | OMIM ID: 603203 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
CCNG2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04068 | FoxO signaling pathway | |
| hsa04115 | p53 signaling pathway |
Expression of CCNG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCNG2 | 901 | 202769_at | -1.0796 | 0.0642 | |
| GSE20347 | CCNG2 | 901 | 202769_at | -2.1040 | 0.0000 | |
| GSE23400 | CCNG2 | 901 | 202769_at | -1.9719 | 0.0000 | |
| GSE26886 | CCNG2 | 901 | 202769_at | -2.3418 | 0.0000 | |
| GSE29001 | CCNG2 | 901 | 202769_at | -1.4548 | 0.0003 | |
| GSE38129 | CCNG2 | 901 | 202769_at | -1.6831 | 0.0000 | |
| GSE45670 | CCNG2 | 901 | 202769_at | -1.0252 | 0.0066 | |
| GSE53622 | CCNG2 | 901 | 19307 | -1.6343 | 0.0000 | |
| GSE53624 | CCNG2 | 901 | 19307 | -2.5934 | 0.0000 | |
| GSE63941 | CCNG2 | 901 | 202769_at | -1.0369 | 0.1176 | |
| GSE77861 | CCNG2 | 901 | 202769_at | -2.3206 | 0.0007 | |
| GSE97050 | CCNG2 | 901 | A_24_P80532 | -0.6082 | 0.2569 | |
| SRP007169 | CCNG2 | 901 | RNAseq | -3.7361 | 0.0000 | |
| SRP008496 | CCNG2 | 901 | RNAseq | -3.6260 | 0.0000 | |
| SRP064894 | CCNG2 | 901 | RNAseq | -2.7138 | 0.0000 | |
| SRP133303 | CCNG2 | 901 | RNAseq | -2.0379 | 0.0000 | |
| SRP159526 | CCNG2 | 901 | RNAseq | -2.2602 | 0.0000 | |
| SRP193095 | CCNG2 | 901 | RNAseq | -2.8379 | 0.0000 | |
| SRP219564 | CCNG2 | 901 | RNAseq | -2.3760 | 0.0004 | |
| TCGA | CCNG2 | 901 | RNAseq | -0.1095 | 0.1855 |
Upregulated datasets: 0; Downregulated datasets: 16.
Survival by CCNG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCNG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCNG2 | 901 | 2 | 9 | 19 | |
| GSE20123 | CCNG2 | 901 | 2 | 9 | 19 | |
| GSE43470 | CCNG2 | 901 | 0 | 13 | 30 | |
| GSE46452 | CCNG2 | 901 | 1 | 36 | 22 | |
| GSE47630 | CCNG2 | 901 | 1 | 19 | 20 | |
| GSE54993 | CCNG2 | 901 | 7 | 0 | 63 | |
| GSE54994 | CCNG2 | 901 | 0 | 9 | 44 | |
| GSE60625 | CCNG2 | 901 | 0 | 0 | 11 | |
| GSE74703 | CCNG2 | 901 | 0 | 11 | 25 | |
| GSE74704 | CCNG2 | 901 | 2 | 5 | 13 | |
| TCGA | CCNG2 | 901 | 16 | 31 | 49 |
Total number of gains: 31; Total number of losses: 142; Total Number of normals: 315.
Somatic mutations of CCNG2:
Generating mutation plots.
Highly correlated genes for CCNG2:
Showing top 20/1874 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCNG2 | SFTA2 | 0.861004 | 4 | 0 | 4 |
| CCNG2 | GYS2 | 0.860679 | 10 | 0 | 10 |
| CCNG2 | BLNK | 0.859484 | 11 | 0 | 11 |
| CCNG2 | SCNN1B | 0.85691 | 10 | 0 | 10 |
| CCNG2 | CYSRT1 | 0.855923 | 6 | 0 | 6 |
| CCNG2 | SPNS2 | 0.853364 | 5 | 0 | 5 |
| CCNG2 | SH3BGRL2 | 0.842364 | 7 | 0 | 7 |
| CCNG2 | CA13 | 0.840792 | 3 | 0 | 3 |
| CCNG2 | TTC9 | 0.840079 | 11 | 0 | 11 |
| CCNG2 | HCG22 | 0.838647 | 6 | 0 | 6 |
| CCNG2 | ARHGAP27 | 0.835981 | 7 | 0 | 7 |
| CCNG2 | SLC16A6 | 0.835688 | 11 | 0 | 11 |
| CCNG2 | HPGD | 0.835194 | 11 | 0 | 11 |
| CCNG2 | UBL3 | 0.83462 | 11 | 0 | 10 |
| CCNG2 | PLEKHA7 | 0.834385 | 7 | 0 | 7 |
| CCNG2 | C18orf25 | 0.833387 | 11 | 0 | 11 |
| CCNG2 | ECM1 | 0.833167 | 10 | 0 | 10 |
| CCNG2 | RNF141 | 0.833125 | 11 | 0 | 11 |
| CCNG2 | VSIG10L | 0.832196 | 6 | 0 | 6 |
| CCNG2 | ENDOU | 0.831839 | 11 | 0 | 11 |
For details and further investigation, click here
