| Full name: USP6 N-terminal like | Alias Symbol: RNTRE|KIAA0019|TRE2NL|RN-tre | ||
| Type: protein-coding gene | Cytoband: 10p14 | ||
| Entrez ID: 9712 | HGNC ID: HGNC:16858 | Ensembl Gene: ENSG00000148429 | OMIM ID: 605405 |
| Drug and gene relationship at DGIdb | |||
Expression of USP6NL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP6NL | 9712 | 204761_at | -1.0902 | 0.2919 | |
| GSE20347 | USP6NL | 9712 | 204761_at | -1.7955 | 0.0000 | |
| GSE23400 | USP6NL | 9712 | 204761_at | -1.1938 | 0.0000 | |
| GSE26886 | USP6NL | 9712 | 204761_at | -2.9881 | 0.0000 | |
| GSE29001 | USP6NL | 9712 | 204761_at | -1.8155 | 0.0000 | |
| GSE38129 | USP6NL | 9712 | 204761_at | -1.1953 | 0.0005 | |
| GSE45670 | USP6NL | 9712 | 204761_at | -0.6642 | 0.0241 | |
| GSE53622 | USP6NL | 9712 | 624 | -1.5657 | 0.0000 | |
| GSE53624 | USP6NL | 9712 | 624 | -1.9480 | 0.0000 | |
| GSE63941 | USP6NL | 9712 | 204761_at | 0.2619 | 0.6036 | |
| GSE77861 | USP6NL | 9712 | 204761_at | -1.7730 | 0.0007 | |
| GSE97050 | USP6NL | 9712 | A_24_P398130 | -0.6664 | 0.2586 | |
| SRP007169 | USP6NL | 9712 | RNAseq | -3.2816 | 0.0000 | |
| SRP008496 | USP6NL | 9712 | RNAseq | -3.0692 | 0.0000 | |
| SRP064894 | USP6NL | 9712 | RNAseq | -2.9615 | 0.0000 | |
| SRP133303 | USP6NL | 9712 | RNAseq | -1.6163 | 0.0000 | |
| SRP159526 | USP6NL | 9712 | RNAseq | -2.5834 | 0.0000 | |
| SRP193095 | USP6NL | 9712 | RNAseq | -2.0107 | 0.0000 | |
| SRP219564 | USP6NL | 9712 | RNAseq | -2.9439 | 0.0000 | |
| TCGA | USP6NL | 9712 | RNAseq | 0.0128 | 0.8653 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by USP6NL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP6NL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP6NL | 9712 | 6 | 7 | 17 | |
| GSE20123 | USP6NL | 9712 | 6 | 6 | 18 | |
| GSE43470 | USP6NL | 9712 | 3 | 5 | 35 | |
| GSE46452 | USP6NL | 9712 | 2 | 14 | 43 | |
| GSE47630 | USP6NL | 9712 | 6 | 14 | 20 | |
| GSE54993 | USP6NL | 9712 | 11 | 0 | 59 | |
| GSE54994 | USP6NL | 9712 | 4 | 9 | 40 | |
| GSE60625 | USP6NL | 9712 | 0 | 0 | 11 | |
| GSE74703 | USP6NL | 9712 | 2 | 3 | 31 | |
| GSE74704 | USP6NL | 9712 | 1 | 5 | 14 | |
| TCGA | USP6NL | 9712 | 19 | 24 | 53 |
Total number of gains: 60; Total number of losses: 87; Total Number of normals: 341.
Somatic mutations of USP6NL:
Generating mutation plots.
Highly correlated genes for USP6NL:
Showing top 20/1928 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP6NL | PRSS2 | 0.851638 | 8 | 0 | 8 |
| USP6NL | RAB11A | 0.847654 | 11 | 0 | 11 |
| USP6NL | IL36A | 0.845068 | 10 | 0 | 10 |
| USP6NL | TAB3 | 0.843651 | 7 | 0 | 7 |
| USP6NL | ARHGAP27 | 0.840459 | 7 | 0 | 7 |
| USP6NL | RANBP9 | 0.839307 | 12 | 0 | 11 |
| USP6NL | ANXA9 | 0.838168 | 11 | 0 | 11 |
| USP6NL | CHP1 | 0.836503 | 10 | 0 | 10 |
| USP6NL | BLNK | 0.833462 | 11 | 0 | 11 |
| USP6NL | ULK3 | 0.832834 | 7 | 0 | 7 |
| USP6NL | EVPL | 0.832254 | 10 | 0 | 10 |
| USP6NL | SLC16A6 | 0.83038 | 11 | 0 | 11 |
| USP6NL | SPNS2 | 0.830031 | 5 | 0 | 5 |
| USP6NL | TTC9 | 0.829396 | 12 | 0 | 11 |
| USP6NL | RMND5B | 0.827127 | 11 | 0 | 11 |
| USP6NL | RASSF5 | 0.826671 | 7 | 0 | 7 |
| USP6NL | CA13 | 0.826547 | 3 | 0 | 3 |
| USP6NL | EPS8L1 | 0.825843 | 11 | 0 | 10 |
| USP6NL | CLIC3 | 0.825265 | 9 | 0 | 9 |
| USP6NL | IMPACT | 0.824605 | 3 | 0 | 3 |
For details and further investigation, click here
