| Full name: cache domain containing 1 | Alias Symbol: KIAA1573 | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 57685 | HGNC ID: HGNC:29314 | Ensembl Gene: ENSG00000158966 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CACHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CACHD1 | 57685 | 225627_s_at | -0.3315 | 0.3168 | |
| GSE26886 | CACHD1 | 57685 | 225627_s_at | 1.8650 | 0.0000 | |
| GSE45670 | CACHD1 | 57685 | 225627_s_at | -0.3750 | 0.3575 | |
| GSE53622 | CACHD1 | 57685 | 24399 | 0.2575 | 0.0713 | |
| GSE53624 | CACHD1 | 57685 | 24399 | 0.1971 | 0.1521 | |
| GSE63941 | CACHD1 | 57685 | 225627_s_at | -0.4094 | 0.7192 | |
| GSE77861 | CACHD1 | 57685 | 234888_at | -0.1809 | 0.1968 | |
| GSE97050 | CACHD1 | 57685 | A_24_P943922 | 0.1481 | 0.4566 | |
| SRP007169 | CACHD1 | 57685 | RNAseq | 2.1223 | 0.0010 | |
| SRP008496 | CACHD1 | 57685 | RNAseq | 2.1953 | 0.0000 | |
| SRP064894 | CACHD1 | 57685 | RNAseq | -0.2096 | 0.4222 | |
| SRP133303 | CACHD1 | 57685 | RNAseq | 0.1050 | 0.7215 | |
| SRP159526 | CACHD1 | 57685 | RNAseq | 0.7807 | 0.1276 | |
| SRP193095 | CACHD1 | 57685 | RNAseq | 0.5363 | 0.0033 | |
| SRP219564 | CACHD1 | 57685 | RNAseq | 0.2297 | 0.5960 | |
| TCGA | CACHD1 | 57685 | RNAseq | -0.3047 | 0.0241 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CACHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CACHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CACHD1 | 57685 | 3 | 6 | 21 | |
| GSE20123 | CACHD1 | 57685 | 3 | 5 | 22 | |
| GSE43470 | CACHD1 | 57685 | 4 | 4 | 35 | |
| GSE46452 | CACHD1 | 57685 | 0 | 1 | 58 | |
| GSE47630 | CACHD1 | 57685 | 8 | 5 | 27 | |
| GSE54993 | CACHD1 | 57685 | 0 | 0 | 70 | |
| GSE54994 | CACHD1 | 57685 | 6 | 4 | 43 | |
| GSE60625 | CACHD1 | 57685 | 0 | 0 | 11 | |
| GSE74703 | CACHD1 | 57685 | 3 | 3 | 30 | |
| GSE74704 | CACHD1 | 57685 | 2 | 2 | 16 | |
| TCGA | CACHD1 | 57685 | 11 | 20 | 65 |
Total number of gains: 40; Total number of losses: 50; Total Number of normals: 398.
Somatic mutations of CACHD1:
Generating mutation plots.
Highly correlated genes for CACHD1:
Showing top 20/117 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CACHD1 | IMMP1L | 0.740146 | 3 | 0 | 3 |
| CACHD1 | CISD3 | 0.721484 | 3 | 0 | 3 |
| CACHD1 | NSMCE4A | 0.720487 | 3 | 0 | 3 |
| CACHD1 | SLC26A10 | 0.714327 | 3 | 0 | 3 |
| CACHD1 | SDR39U1 | 0.710611 | 4 | 0 | 3 |
| CACHD1 | ZNF703 | 0.707209 | 3 | 0 | 3 |
| CACHD1 | C19orf54 | 0.702878 | 3 | 0 | 3 |
| CACHD1 | CAPN3 | 0.701651 | 3 | 0 | 3 |
| CACHD1 | GTDC1 | 0.697751 | 5 | 0 | 4 |
| CACHD1 | NDUFAF3 | 0.694475 | 3 | 0 | 3 |
| CACHD1 | TSNARE1 | 0.692746 | 3 | 0 | 3 |
| CACHD1 | LYRM7 | 0.690002 | 3 | 0 | 3 |
| CACHD1 | PAQR7 | 0.68949 | 3 | 0 | 3 |
| CACHD1 | IRX1 | 0.679662 | 3 | 0 | 3 |
| CACHD1 | ITGB1BP1 | 0.678975 | 3 | 0 | 3 |
| CACHD1 | MTMR6 | 0.678647 | 3 | 0 | 3 |
| CACHD1 | TK2 | 0.677691 | 3 | 0 | 3 |
| CACHD1 | SIN3A | 0.675258 | 3 | 0 | 3 |
| CACHD1 | RNASEH2C | 0.66754 | 4 | 0 | 3 |
| CACHD1 | IFT81 | 0.666407 | 4 | 0 | 4 |
For details and further investigation, click here
