| Full name: myotubularin related protein 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q12.13 | ||
| Entrez ID: 9107 | HGNC ID: HGNC:7453 | Ensembl Gene: ENSG00000139505 | OMIM ID: 603561 |
| Drug and gene relationship at DGIdb | |||
Expression of MTMR6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTMR6 | 9107 | 214429_at | -0.2700 | 0.5663 | |
| GSE20347 | MTMR6 | 9107 | 214429_at | -0.2329 | 0.1548 | |
| GSE23400 | MTMR6 | 9107 | 214429_at | -0.0925 | 0.2970 | |
| GSE26886 | MTMR6 | 9107 | 214429_at | 0.1589 | 0.6275 | |
| GSE29001 | MTMR6 | 9107 | 214429_at | -0.2179 | 0.3537 | |
| GSE38129 | MTMR6 | 9107 | 214429_at | -0.3134 | 0.0379 | |
| GSE45670 | MTMR6 | 9107 | 214429_at | -0.3038 | 0.0146 | |
| GSE53622 | MTMR6 | 9107 | 44407 | -0.2116 | 0.0024 | |
| GSE53624 | MTMR6 | 9107 | 44407 | -0.2852 | 0.0011 | |
| GSE63941 | MTMR6 | 9107 | 214429_at | -1.5211 | 0.0041 | |
| GSE77861 | MTMR6 | 9107 | 214429_at | -0.2673 | 0.2890 | |
| GSE97050 | MTMR6 | 9107 | A_24_P419211 | 0.1325 | 0.5580 | |
| SRP007169 | MTMR6 | 9107 | RNAseq | -0.5300 | 0.1624 | |
| SRP008496 | MTMR6 | 9107 | RNAseq | -0.1880 | 0.4495 | |
| SRP064894 | MTMR6 | 9107 | RNAseq | -0.0580 | 0.7863 | |
| SRP133303 | MTMR6 | 9107 | RNAseq | 0.0971 | 0.5545 | |
| SRP159526 | MTMR6 | 9107 | RNAseq | -0.5756 | 0.0562 | |
| SRP193095 | MTMR6 | 9107 | RNAseq | -0.2685 | 0.0704 | |
| SRP219564 | MTMR6 | 9107 | RNAseq | -0.2503 | 0.4782 | |
| TCGA | MTMR6 | 9107 | RNAseq | -0.2522 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MTMR6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTMR6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTMR6 | 9107 | 1 | 12 | 17 | |
| GSE20123 | MTMR6 | 9107 | 1 | 11 | 18 | |
| GSE43470 | MTMR6 | 9107 | 2 | 12 | 29 | |
| GSE46452 | MTMR6 | 9107 | 0 | 33 | 26 | |
| GSE47630 | MTMR6 | 9107 | 3 | 26 | 11 | |
| GSE54993 | MTMR6 | 9107 | 11 | 2 | 57 | |
| GSE54994 | MTMR6 | 9107 | 1 | 13 | 39 | |
| GSE60625 | MTMR6 | 9107 | 0 | 3 | 8 | |
| GSE74703 | MTMR6 | 9107 | 2 | 9 | 25 | |
| GSE74704 | MTMR6 | 9107 | 0 | 9 | 11 | |
| TCGA | MTMR6 | 9107 | 5 | 46 | 45 |
Total number of gains: 26; Total number of losses: 176; Total Number of normals: 286.
Somatic mutations of MTMR6:
Generating mutation plots.
Highly correlated genes for MTMR6:
Showing top 20/906 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTMR6 | DNAJC15 | 0.756448 | 4 | 0 | 4 |
| MTMR6 | TGFBR1 | 0.752874 | 3 | 0 | 3 |
| MTMR6 | C11orf96 | 0.749846 | 3 | 0 | 3 |
| MTMR6 | RGS18 | 0.741756 | 3 | 0 | 3 |
| MTMR6 | DPH3 | 0.741153 | 4 | 0 | 3 |
| MTMR6 | AMOTL1 | 0.731768 | 4 | 0 | 3 |
| MTMR6 | CASP8AP2 | 0.731001 | 3 | 0 | 3 |
| MTMR6 | ZNF583 | 0.724666 | 3 | 0 | 3 |
| MTMR6 | UTP14C | 0.723 | 4 | 0 | 3 |
| MTMR6 | CPEB4 | 0.720434 | 3 | 0 | 3 |
| MTMR6 | PLEKHM3 | 0.719631 | 3 | 0 | 3 |
| MTMR6 | CCDC68 | 0.719191 | 3 | 0 | 3 |
| MTMR6 | SMPD1 | 0.718162 | 4 | 0 | 3 |
| MTMR6 | ROBO1 | 0.715484 | 3 | 0 | 3 |
| MTMR6 | CPVL | 0.715026 | 4 | 0 | 4 |
| MTMR6 | DDHD1 | 0.713708 | 3 | 0 | 3 |
| MTMR6 | INSIG1 | 0.712213 | 4 | 0 | 4 |
| MTMR6 | CDC40 | 0.710784 | 4 | 0 | 3 |
| MTMR6 | PIGH | 0.707694 | 3 | 0 | 3 |
| MTMR6 | RORA | 0.705524 | 3 | 0 | 3 |
For details and further investigation, click here
