| Full name: calcium voltage-gated channel auxiliary subunit gamma 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 59285 | HGNC ID: HGNC:13625 | Ensembl Gene: ENSG00000130433 | OMIM ID: 606898 |
| Drug and gene relationship at DGIdb | |||
CACNG6 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04010 | MAPK signaling pathway | |
| hsa04261 | Adrenergic signaling in cardiomyocytes | |
| hsa04921 | Oxytocin signaling pathway |
Expression of CACNG6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CACNG6 | 59285 | 1552863_a_at | -0.1930 | 0.5745 | |
| GSE26886 | CACNG6 | 59285 | 1552863_a_at | -0.5689 | 0.0007 | |
| GSE45670 | CACNG6 | 59285 | 1552863_a_at | -0.1271 | 0.2655 | |
| GSE53622 | CACNG6 | 59285 | 48430 | -0.0242 | 0.8797 | |
| GSE53624 | CACNG6 | 59285 | 48430 | 0.2491 | 0.0480 | |
| GSE63941 | CACNG6 | 59285 | 1552863_a_at | 0.1679 | 0.3104 | |
| GSE77861 | CACNG6 | 59285 | 1552863_a_at | -0.2469 | 0.1050 | |
| TCGA | CACNG6 | 59285 | RNAseq | -1.0025 | 0.5780 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CACNG6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CACNG6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CACNG6 | 59285 | 3 | 4 | 23 | |
| GSE20123 | CACNG6 | 59285 | 3 | 3 | 24 | |
| GSE43470 | CACNG6 | 59285 | 2 | 11 | 30 | |
| GSE46452 | CACNG6 | 59285 | 45 | 1 | 13 | |
| GSE47630 | CACNG6 | 59285 | 8 | 6 | 26 | |
| GSE54993 | CACNG6 | 59285 | 17 | 4 | 49 | |
| GSE54994 | CACNG6 | 59285 | 4 | 14 | 35 | |
| GSE60625 | CACNG6 | 59285 | 9 | 0 | 2 | |
| GSE74703 | CACNG6 | 59285 | 2 | 7 | 27 | |
| GSE74704 | CACNG6 | 59285 | 3 | 1 | 16 | |
| TCGA | CACNG6 | 59285 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 66; Total Number of normals: 307.
Somatic mutations of CACNG6:
Generating mutation plots.
Highly correlated genes for CACNG6:
Showing top 20/398 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CACNG6 | TIMM23 | 0.763007 | 3 | 0 | 3 |
| CACNG6 | SPATA16 | 0.746512 | 3 | 0 | 3 |
| CACNG6 | ESAM | 0.74036 | 3 | 0 | 3 |
| CACNG6 | C2orf16 | 0.726873 | 5 | 0 | 5 |
| CACNG6 | A1CF | 0.719986 | 4 | 0 | 4 |
| CACNG6 | UBAP1 | 0.71553 | 4 | 0 | 4 |
| CACNG6 | MAPK12 | 0.711738 | 4 | 0 | 4 |
| CACNG6 | SAMD15 | 0.704744 | 4 | 0 | 4 |
| CACNG6 | TMEM222 | 0.703173 | 3 | 0 | 3 |
| CACNG6 | CALCR | 0.702828 | 3 | 0 | 3 |
| CACNG6 | RNF208 | 0.700382 | 4 | 0 | 4 |
| CACNG6 | CNR2 | 0.697809 | 5 | 0 | 5 |
| CACNG6 | SOX10 | 0.693369 | 5 | 0 | 5 |
| CACNG6 | ARMC4 | 0.688586 | 3 | 0 | 3 |
| CACNG6 | GAS8 | 0.683858 | 3 | 0 | 3 |
| CACNG6 | GFOD2 | 0.680158 | 3 | 0 | 3 |
| CACNG6 | ICOSLG | 0.675243 | 4 | 0 | 4 |
| CACNG6 | ANKRD34A | 0.674173 | 3 | 0 | 3 |
| CACNG6 | GRTP1-AS1 | 0.673172 | 3 | 0 | 3 |
| CACNG6 | ASB10 | 0.672987 | 5 | 0 | 4 |
For details and further investigation, click here
