| Full name: ubiquitin associated protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 51271 | HGNC ID: HGNC:12461 | Ensembl Gene: ENSG00000165006 | OMIM ID: 609787 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UBAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBAP1 | 51271 | 221490_at | -0.6311 | 0.0955 | |
| GSE20347 | UBAP1 | 51271 | 221490_at | -0.7156 | 0.0000 | |
| GSE23400 | UBAP1 | 51271 | 221490_at | -0.4838 | 0.0000 | |
| GSE26886 | UBAP1 | 51271 | 221490_at | -1.1630 | 0.0000 | |
| GSE29001 | UBAP1 | 51271 | 221490_at | -0.7914 | 0.0013 | |
| GSE38129 | UBAP1 | 51271 | 221490_at | -0.7073 | 0.0000 | |
| GSE45670 | UBAP1 | 51271 | 221490_at | -0.3742 | 0.0178 | |
| GSE53622 | UBAP1 | 51271 | 1465 | -0.6674 | 0.0000 | |
| GSE53624 | UBAP1 | 51271 | 1465 | -0.7167 | 0.0000 | |
| GSE63941 | UBAP1 | 51271 | 221490_at | 0.0811 | 0.8475 | |
| GSE77861 | UBAP1 | 51271 | 221490_at | -0.5534 | 0.0758 | |
| GSE97050 | UBAP1 | 51271 | A_23_P123866 | -0.1652 | 0.5726 | |
| SRP007169 | UBAP1 | 51271 | RNAseq | -1.9681 | 0.0000 | |
| SRP008496 | UBAP1 | 51271 | RNAseq | -1.8302 | 0.0000 | |
| SRP064894 | UBAP1 | 51271 | RNAseq | -1.2064 | 0.0000 | |
| SRP133303 | UBAP1 | 51271 | RNAseq | -0.6773 | 0.0003 | |
| SRP159526 | UBAP1 | 51271 | RNAseq | -1.4974 | 0.0000 | |
| SRP193095 | UBAP1 | 51271 | RNAseq | -1.1781 | 0.0000 | |
| SRP219564 | UBAP1 | 51271 | RNAseq | -0.7893 | 0.0563 | |
| TCGA | UBAP1 | 51271 | RNAseq | -0.0293 | 0.6099 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by UBAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBAP1 | 51271 | 3 | 14 | 13 | |
| GSE20123 | UBAP1 | 51271 | 3 | 14 | 13 | |
| GSE43470 | UBAP1 | 51271 | 3 | 10 | 30 | |
| GSE46452 | UBAP1 | 51271 | 6 | 15 | 38 | |
| GSE47630 | UBAP1 | 51271 | 1 | 20 | 19 | |
| GSE54993 | UBAP1 | 51271 | 6 | 0 | 64 | |
| GSE54994 | UBAP1 | 51271 | 6 | 12 | 35 | |
| GSE60625 | UBAP1 | 51271 | 0 | 0 | 11 | |
| GSE74703 | UBAP1 | 51271 | 2 | 7 | 27 | |
| GSE74704 | UBAP1 | 51271 | 0 | 11 | 9 | |
| TCGA | UBAP1 | 51271 | 16 | 44 | 36 |
Total number of gains: 46; Total number of losses: 147; Total Number of normals: 295.
Somatic mutations of UBAP1:
Generating mutation plots.
Highly correlated genes for UBAP1:
Showing top 20/1468 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBAP1 | PIM1 | 0.761218 | 12 | 0 | 12 |
| UBAP1 | PDCD6IP | 0.75414 | 10 | 0 | 10 |
| UBAP1 | DCAF12 | 0.74989 | 7 | 0 | 7 |
| UBAP1 | TMEM79 | 0.74904 | 5 | 0 | 5 |
| UBAP1 | NLRX1 | 0.747547 | 10 | 0 | 10 |
| UBAP1 | WDFY1 | 0.74567 | 3 | 0 | 3 |
| UBAP1 | SH3GL1 | 0.745576 | 11 | 0 | 11 |
| UBAP1 | APOB | 0.745331 | 5 | 0 | 4 |
| UBAP1 | TRIP10 | 0.744988 | 11 | 0 | 11 |
| UBAP1 | FAM95B1 | 0.742182 | 3 | 0 | 3 |
| UBAP1 | KRT37 | 0.741513 | 3 | 0 | 3 |
| UBAP1 | SNX12 | 0.74129 | 3 | 0 | 3 |
| UBAP1 | ADAMTS9 | 0.741226 | 3 | 0 | 3 |
| UBAP1 | ECM1 | 0.739528 | 10 | 0 | 10 |
| UBAP1 | ITPKC | 0.734688 | 11 | 0 | 10 |
| UBAP1 | ARSG | 0.734502 | 3 | 0 | 3 |
| UBAP1 | GYS2 | 0.733688 | 10 | 0 | 10 |
| UBAP1 | KANK1 | 0.733658 | 12 | 0 | 11 |
| UBAP1 | MXD1 | 0.731009 | 12 | 0 | 11 |
| UBAP1 | LEPROT | 0.730879 | 4 | 0 | 3 |
For details and further investigation, click here
