| Full name: endothelial cell adhesion molecule | Alias Symbol: W117m | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 90952 | HGNC ID: HGNC:17474 | Ensembl Gene: ENSG00000149564 | OMIM ID: 614281 |
| Drug and gene relationship at DGIdb | |||
Expression of ESAM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ESAM | 90952 | 225369_at | -0.3666 | 0.5394 | |
| GSE26886 | ESAM | 90952 | 225369_at | -1.2270 | 0.0001 | |
| GSE45670 | ESAM | 90952 | 225369_at | -0.5893 | 0.0044 | |
| GSE53622 | ESAM | 90952 | 137276 | -0.7742 | 0.0000 | |
| GSE53624 | ESAM | 90952 | 114368 | -1.1967 | 0.0000 | |
| GSE63941 | ESAM | 90952 | 225369_at | 0.0498 | 0.8420 | |
| GSE77861 | ESAM | 90952 | 225369_at | -0.7024 | 0.0104 | |
| GSE97050 | ESAM | 90952 | A_23_P47410 | 0.0331 | 0.9254 | |
| SRP007169 | ESAM | 90952 | RNAseq | -4.0096 | 0.0000 | |
| SRP008496 | ESAM | 90952 | RNAseq | -3.2544 | 0.0000 | |
| SRP064894 | ESAM | 90952 | RNAseq | -0.6661 | 0.0251 | |
| SRP133303 | ESAM | 90952 | RNAseq | -1.4566 | 0.0000 | |
| SRP159526 | ESAM | 90952 | RNAseq | -0.9445 | 0.0050 | |
| SRP193095 | ESAM | 90952 | RNAseq | -1.4882 | 0.0000 | |
| SRP219564 | ESAM | 90952 | RNAseq | -0.8584 | 0.0644 | |
| TCGA | ESAM | 90952 | RNAseq | -0.4461 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by ESAM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ESAM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ESAM | 90952 | 0 | 13 | 17 | |
| GSE20123 | ESAM | 90952 | 0 | 13 | 17 | |
| GSE43470 | ESAM | 90952 | 2 | 7 | 34 | |
| GSE46452 | ESAM | 90952 | 3 | 26 | 30 | |
| GSE47630 | ESAM | 90952 | 2 | 19 | 19 | |
| GSE54993 | ESAM | 90952 | 10 | 0 | 60 | |
| GSE54994 | ESAM | 90952 | 5 | 19 | 29 | |
| GSE60625 | ESAM | 90952 | 0 | 3 | 8 | |
| GSE74703 | ESAM | 90952 | 1 | 5 | 30 | |
| GSE74704 | ESAM | 90952 | 0 | 9 | 11 | |
| TCGA | ESAM | 90952 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of ESAM:
Generating mutation plots.
Highly correlated genes for ESAM:
Showing top 20/514 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ESAM | SHROOM4 | 0.752355 | 3 | 0 | 3 |
| ESAM | SEMA5B | 0.745427 | 3 | 0 | 3 |
| ESAM | CACNG6 | 0.74036 | 3 | 0 | 3 |
| ESAM | CCDC157 | 0.737298 | 3 | 0 | 3 |
| ESAM | BTBD19 | 0.730875 | 3 | 0 | 3 |
| ESAM | SH3GL1 | 0.714608 | 5 | 0 | 4 |
| ESAM | SNX9 | 0.712597 | 5 | 0 | 5 |
| ESAM | UBL3 | 0.711372 | 5 | 0 | 5 |
| ESAM | ASB10 | 0.710142 | 3 | 0 | 3 |
| ESAM | GMDS | 0.705361 | 5 | 0 | 5 |
| ESAM | TCL6 | 0.702665 | 3 | 0 | 3 |
| ESAM | FLG | 0.70252 | 5 | 0 | 5 |
| ESAM | GDPD3 | 0.702168 | 5 | 0 | 5 |
| ESAM | SRD5A3-AS1 | 0.699161 | 3 | 0 | 3 |
| ESAM | CDH5 | 0.698456 | 4 | 0 | 4 |
| ESAM | ABLIM3 | 0.697775 | 7 | 0 | 7 |
| ESAM | KRT78 | 0.697406 | 5 | 0 | 5 |
| ESAM | PMM1 | 0.691469 | 7 | 0 | 7 |
| ESAM | SLC8A1-AS1 | 0.690184 | 5 | 0 | 5 |
| ESAM | GAB2 | 0.68981 | 7 | 0 | 7 |
For details and further investigation, click here
