| Full name: MYC target 1 | Alias Symbol: MTLC|FLJ21269 | ||
| Type: protein-coding gene | Cytoband: 6q25.2 | ||
| Entrez ID: 80177 | HGNC ID: HGNC:23172 | Ensembl Gene: ENSG00000120279 | OMIM ID: 616805 |
| Drug and gene relationship at DGIdb | |||
Expression of MYCT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYCT1 | 80177 | 231947_at | -0.6890 | 0.1406 | |
| GSE20347 | MYCT1 | 80177 | 220471_s_at | -0.0729 | 0.1390 | |
| GSE23400 | MYCT1 | 80177 | 220471_s_at | -0.1175 | 0.0000 | |
| GSE26886 | MYCT1 | 80177 | 220471_s_at | 0.0031 | 0.9801 | |
| GSE29001 | MYCT1 | 80177 | 220471_s_at | -0.0803 | 0.5044 | |
| GSE38129 | MYCT1 | 80177 | 220471_s_at | -0.2552 | 0.0049 | |
| GSE45670 | MYCT1 | 80177 | 231947_at | -1.6964 | 0.0001 | |
| GSE53622 | MYCT1 | 80177 | 5082 | -1.0917 | 0.0000 | |
| GSE53624 | MYCT1 | 80177 | 5082 | -0.6639 | 0.0058 | |
| GSE63941 | MYCT1 | 80177 | 220471_s_at | -0.1952 | 0.0678 | |
| GSE77861 | MYCT1 | 80177 | 220471_s_at | -0.0392 | 0.7012 | |
| GSE97050 | MYCT1 | 80177 | A_24_P945059 | 0.0175 | 0.9543 | |
| SRP007169 | MYCT1 | 80177 | RNAseq | 0.4831 | 0.3014 | |
| SRP064894 | MYCT1 | 80177 | RNAseq | 0.3729 | 0.2790 | |
| SRP133303 | MYCT1 | 80177 | RNAseq | -0.6007 | 0.0182 | |
| SRP159526 | MYCT1 | 80177 | RNAseq | -0.3500 | 0.4610 | |
| SRP193095 | MYCT1 | 80177 | RNAseq | 0.0353 | 0.7746 | |
| SRP219564 | MYCT1 | 80177 | RNAseq | 0.1750 | 0.7700 | |
| TCGA | MYCT1 | 80177 | RNAseq | -0.6324 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MYCT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYCT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYCT1 | 80177 | 1 | 4 | 25 | |
| GSE20123 | MYCT1 | 80177 | 1 | 3 | 26 | |
| GSE43470 | MYCT1 | 80177 | 4 | 0 | 39 | |
| GSE46452 | MYCT1 | 80177 | 3 | 10 | 46 | |
| GSE47630 | MYCT1 | 80177 | 9 | 4 | 27 | |
| GSE54993 | MYCT1 | 80177 | 3 | 2 | 65 | |
| GSE54994 | MYCT1 | 80177 | 8 | 8 | 37 | |
| GSE60625 | MYCT1 | 80177 | 0 | 1 | 10 | |
| GSE74703 | MYCT1 | 80177 | 4 | 0 | 32 | |
| GSE74704 | MYCT1 | 80177 | 0 | 1 | 19 | |
| TCGA | MYCT1 | 80177 | 11 | 21 | 64 |
Total number of gains: 44; Total number of losses: 54; Total Number of normals: 390.
Somatic mutations of MYCT1:
Generating mutation plots.
Highly correlated genes for MYCT1:
Showing top 20/906 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYCT1 | EBF1 | 0.828862 | 6 | 0 | 6 |
| MYCT1 | GIMAP5 | 0.791124 | 3 | 0 | 3 |
| MYCT1 | C11orf96 | 0.7857 | 4 | 0 | 4 |
| MYCT1 | EBF3 | 0.783672 | 5 | 0 | 5 |
| MYCT1 | KLF11 | 0.781204 | 3 | 0 | 3 |
| MYCT1 | GIMAP8 | 0.765203 | 5 | 0 | 4 |
| MYCT1 | MMRN1 | 0.762245 | 6 | 0 | 6 |
| MYCT1 | NLRP12 | 0.758742 | 3 | 0 | 3 |
| MYCT1 | EPDR1 | 0.757487 | 4 | 0 | 3 |
| MYCT1 | GPIHBP1 | 0.747048 | 4 | 0 | 4 |
| MYCT1 | CYYR1 | 0.743965 | 6 | 0 | 5 |
| MYCT1 | TMEM132C | 0.742244 | 4 | 0 | 4 |
| MYCT1 | RCSD1 | 0.737949 | 5 | 0 | 5 |
| MYCT1 | WIPF1 | 0.737679 | 3 | 0 | 3 |
| MYCT1 | CADPS2 | 0.734106 | 3 | 0 | 3 |
| MYCT1 | MYADM | 0.733197 | 3 | 0 | 3 |
| MYCT1 | APOLD1 | 0.733087 | 6 | 0 | 6 |
| MYCT1 | CD63 | 0.732139 | 4 | 0 | 3 |
| MYCT1 | BIVM | 0.728918 | 3 | 0 | 3 |
| MYCT1 | TCEA2 | 0.727991 | 3 | 0 | 3 |
For details and further investigation, click here
