CAMK2N2

 

Full name: calcium/calmodulin dependent protein kinase II inhibitor 2 Alias Symbol: CaM-KIIN
Type: protein-coding gene Cytoband: 3q27.1
Entrez ID: 94032 HGNC ID: HGNC:24197 Ensembl Gene: ENSG00000163888 OMIM ID: 608721
Drug and gene relationship at DGIdb

 

Expression of CAMK2N2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CAMK2N2 94032 1552893_at -0.1623 0.4031
GSE26886 CAMK2N2 94032 1552893_at 0.1169 0.1969
GSE45670 CAMK2N2 94032 1552893_at 0.0411 0.6124
GSE63941 CAMK2N2 94032 230706_s_at 0.2608 0.6457
GSE77861 CAMK2N2 94032 230706_s_at 0.0285 0.8832
GSE97050 CAMK2N2 94032 A_33_P3244283 0.6254 0.2037
SRP133303 CAMK2N2 94032 RNAseq 2.1629 0.0000
SRP219564 CAMK2N2 94032 RNAseq 2.2018 0.0024
TCGA CAMK2N2 94032 RNAseq 0.8288 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by CAMK2N2 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of CAMK2N2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CAMK2N2 94032 25 0 5
GSE20123 CAMK2N2 94032 25 0 5
GSE43470 CAMK2N2 94032 25 0 18
GSE46452 CAMK2N2 94032 19 1 39
GSE47630 CAMK2N2 94032 27 2 11
GSE54993 CAMK2N2 94032 1 19 50
GSE54994 CAMK2N2 94032 41 0 12
GSE60625 CAMK2N2 94032 0 6 5
GSE74703 CAMK2N2 94032 21 0 15
GSE74704 CAMK2N2 94032 17 0 3
TCGA CAMK2N2 94032 77 0 19

Total number of gains: 278; Total number of losses: 28; Total Number of normals: 182.  


 

Somatic mutations of CAMK2N2:

 

Generating mutation plots.

 

Highly correlated genes for CAMK2N2:

 

Showing top 20/66 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CAMK2N2GSX10.761334303
CAMK2N2SYN10.740741303
CAMK2N2CIITA0.678391404
CAMK2N2LCN150.676409303
CAMK2N2TAL20.676194303
CAMK2N2FOXP30.674329303
CAMK2N2EPOR0.65127303
CAMK2N2NUTM10.651029303
CAMK2N2ATXN2L0.646933303
CAMK2N2THEG0.645338303
CAMK2N2PRAMEF110.644359303
CAMK2N2KCNJ140.642482303
CAMK2N2LINC011180.642421303
CAMK2N2GABRA10.636474303
CAMK2N2RABEP20.633556303
CAMK2N2APBA10.632167403
CAMK2N2FGF10.625545303
CAMK2N2LEPR0.624229403
CAMK2N2DLL40.623007303
CAMK2N2SLC34A30.618281303

For details and further investigation, click here