| Full name: calponin 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p21.3 | ||
| Entrez ID: 1266 | HGNC ID: HGNC:2157 | Ensembl Gene: ENSG00000117519 | OMIM ID: 602374 |
| Drug and gene relationship at DGIdb | |||
Expression of CNN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE20347 | CNN3 | 1266 | 201445_at | -2.2062 | 0.0000 | |
| GSE23400 | CNN3 | 1266 | 201445_at | -1.3018 | 0.0000 | |
| GSE26886 | CNN3 | 1266 | 201445_at | -3.8499 | 0.0000 | |
| GSE29001 | CNN3 | 1266 | 201445_at | -2.2758 | 0.0001 | |
| GSE38129 | CNN3 | 1266 | 201445_at | -1.5834 | 0.0000 | |
| GSE45670 | CNN3 | 1266 | 201445_at | -1.4037 | 0.0000 | |
| GSE53622 | CNN3 | 1266 | 10981 | -0.9406 | 0.0000 | |
| GSE53624 | CNN3 | 1266 | 10981 | -1.3976 | 0.0000 | |
| GSE97050 | CNN3 | 1266 | A_23_P138168 | -0.4199 | 0.3673 | |
| SRP007169 | CNN3 | 1266 | RNAseq | -2.6653 | 0.0000 | |
| SRP008496 | CNN3 | 1266 | RNAseq | -2.1681 | 0.0000 | |
| SRP064894 | CNN3 | 1266 | RNAseq | -0.9985 | 0.0000 | |
| SRP133303 | CNN3 | 1266 | RNAseq | -0.9019 | 0.0003 | |
| SRP159526 | CNN3 | 1266 | RNAseq | -1.5150 | 0.0000 | |
| SRP193095 | CNN3 | 1266 | RNAseq | -0.9137 | 0.0022 | |
| SRP219564 | CNN3 | 1266 | RNAseq | -0.7011 | 0.0885 | |
| TCGA | CNN3 | 1266 | RNAseq | -0.2015 | 0.0107 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by CNN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNN3 | 1266 | 0 | 8 | 22 | |
| GSE20123 | CNN3 | 1266 | 0 | 8 | 22 | |
| GSE43470 | CNN3 | 1266 | 2 | 6 | 35 | |
| GSE46452 | CNN3 | 1266 | 1 | 1 | 57 | |
| GSE47630 | CNN3 | 1266 | 8 | 5 | 27 | |
| GSE54993 | CNN3 | 1266 | 0 | 1 | 69 | |
| GSE54994 | CNN3 | 1266 | 6 | 3 | 44 | |
| GSE60625 | CNN3 | 1266 | 0 | 0 | 11 | |
| GSE74703 | CNN3 | 1266 | 1 | 5 | 30 | |
| GSE74704 | CNN3 | 1266 | 0 | 5 | 15 | |
| TCGA | CNN3 | 1266 | 6 | 24 | 66 |
Total number of gains: 24; Total number of losses: 66; Total Number of normals: 398.
Somatic mutations of CNN3:
Generating mutation plots.
Highly correlated genes for CNN3:
Showing top 20/1711 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNN3 | RHOA | 0.819363 | 9 | 0 | 9 |
| CNN3 | UBL3 | 0.816623 | 8 | 0 | 8 |
| CNN3 | PDLIM2 | 0.814735 | 7 | 0 | 7 |
| CNN3 | EPB41L3 | 0.808092 | 9 | 0 | 9 |
| CNN3 | RBM20 | 0.802014 | 3 | 0 | 3 |
| CNN3 | FCHO2 | 0.79985 | 5 | 0 | 5 |
| CNN3 | CTTNBP2NL | 0.794465 | 5 | 0 | 5 |
| CNN3 | ZNF416 | 0.785931 | 3 | 0 | 3 |
| CNN3 | SYTL4 | 0.78288 | 3 | 0 | 3 |
| CNN3 | KRT78 | 0.780336 | 4 | 0 | 4 |
| CNN3 | SHROOM3 | 0.779236 | 5 | 0 | 5 |
| CNN3 | CCNG2 | 0.777777 | 9 | 0 | 9 |
| CNN3 | TMOD3 | 0.773532 | 8 | 0 | 8 |
| CNN3 | LMBRD1 | 0.77314 | 9 | 0 | 9 |
| CNN3 | KAT2B | 0.771497 | 9 | 0 | 9 |
| CNN3 | A2ML1 | 0.769516 | 4 | 0 | 4 |
| CNN3 | CCDC6 | 0.768593 | 8 | 0 | 8 |
| CNN3 | EHD3 | 0.767968 | 9 | 0 | 9 |
| CNN3 | ELMO2 | 0.767291 | 9 | 0 | 9 |
| CNN3 | BRK1 | 0.767009 | 5 | 0 | 5 |
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