| Full name: caspase recruitment domain family member 10 | Alias Symbol: CARMA3|BIMP1 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 29775 | HGNC ID: HGNC:16422 | Ensembl Gene: ENSG00000100065 | OMIM ID: 607209 |
| Drug and gene relationship at DGIdb | |||
Expression of CARD10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CARD10 | 29775 | 210026_s_at | 0.7376 | 0.3593 | |
| GSE20347 | CARD10 | 29775 | 210026_s_at | 0.5429 | 0.2421 | |
| GSE23400 | CARD10 | 29775 | 210025_s_at | -0.0463 | 0.2236 | |
| GSE26886 | CARD10 | 29775 | 210026_s_at | 1.7202 | 0.0000 | |
| GSE29001 | CARD10 | 29775 | 210026_s_at | 0.9956 | 0.0505 | |
| GSE38129 | CARD10 | 29775 | 210026_s_at | 0.3687 | 0.2863 | |
| GSE45670 | CARD10 | 29775 | 210026_s_at | 0.6685 | 0.0906 | |
| GSE53622 | CARD10 | 29775 | 92497 | 0.4276 | 0.0000 | |
| GSE53624 | CARD10 | 29775 | 92497 | 0.4768 | 0.0000 | |
| GSE63941 | CARD10 | 29775 | 210026_s_at | 3.1579 | 0.0003 | |
| GSE77861 | CARD10 | 29775 | 210026_s_at | 0.9077 | 0.2019 | |
| GSE97050 | CARD10 | 29775 | A_23_P434890 | 0.1527 | 0.4505 | |
| SRP007169 | CARD10 | 29775 | RNAseq | 1.7765 | 0.0049 | |
| SRP008496 | CARD10 | 29775 | RNAseq | 1.6414 | 0.0028 | |
| SRP064894 | CARD10 | 29775 | RNAseq | 0.7988 | 0.0148 | |
| SRP133303 | CARD10 | 29775 | RNAseq | 0.7350 | 0.0337 | |
| SRP159526 | CARD10 | 29775 | RNAseq | 0.3873 | 0.3771 | |
| SRP193095 | CARD10 | 29775 | RNAseq | 1.0897 | 0.0000 | |
| SRP219564 | CARD10 | 29775 | RNAseq | 0.3542 | 0.5575 | |
| TCGA | CARD10 | 29775 | RNAseq | 0.0698 | 0.5589 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by CARD10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CARD10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CARD10 | 29775 | 6 | 6 | 18 | |
| GSE20123 | CARD10 | 29775 | 6 | 5 | 19 | |
| GSE43470 | CARD10 | 29775 | 4 | 6 | 33 | |
| GSE46452 | CARD10 | 29775 | 32 | 2 | 25 | |
| GSE47630 | CARD10 | 29775 | 9 | 4 | 27 | |
| GSE54993 | CARD10 | 29775 | 3 | 6 | 61 | |
| GSE54994 | CARD10 | 29775 | 9 | 8 | 36 | |
| GSE60625 | CARD10 | 29775 | 5 | 0 | 6 | |
| GSE74703 | CARD10 | 29775 | 4 | 4 | 28 | |
| GSE74704 | CARD10 | 29775 | 3 | 2 | 15 | |
| TCGA | CARD10 | 29775 | 27 | 15 | 54 |
Total number of gains: 108; Total number of losses: 58; Total Number of normals: 322.
Somatic mutations of CARD10:
Generating mutation plots.
Highly correlated genes for CARD10:
Showing top 20/1043 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CARD10 | OR2T12 | 0.816659 | 3 | 0 | 3 |
| CARD10 | UBTD2 | 0.771633 | 4 | 0 | 4 |
| CARD10 | TMEM60 | 0.763487 | 3 | 0 | 3 |
| CARD10 | PPP6R3 | 0.759119 | 3 | 0 | 3 |
| CARD10 | CPT1C | 0.752226 | 3 | 0 | 3 |
| CARD10 | NEK6 | 0.746326 | 3 | 0 | 3 |
| CARD10 | ELFN1 | 0.727448 | 5 | 0 | 5 |
| CARD10 | ADAM10 | 0.716738 | 4 | 0 | 3 |
| CARD10 | NUDT5 | 0.713782 | 3 | 0 | 3 |
| CARD10 | UBA6 | 0.711059 | 4 | 0 | 3 |
| CARD10 | MGAT4B | 0.708971 | 3 | 0 | 3 |
| CARD10 | SRRT | 0.707068 | 3 | 0 | 3 |
| CARD10 | RTTN | 0.705822 | 4 | 0 | 4 |
| CARD10 | SF3A2 | 0.705338 | 3 | 0 | 3 |
| CARD10 | KLHL13 | 0.703465 | 3 | 0 | 3 |
| CARD10 | SPI1 | 0.702259 | 3 | 0 | 3 |
| CARD10 | DARS2 | 0.697295 | 5 | 0 | 4 |
| CARD10 | DOT1L | 0.696118 | 4 | 0 | 4 |
| CARD10 | BATF3 | 0.694239 | 3 | 0 | 3 |
| CARD10 | UHRF1BP1 | 0.691852 | 3 | 0 | 3 |
For details and further investigation, click here
