| Full name: nudix hydrolase 5 | Alias Symbol: hYSAH1|YSA1H | ||
| Type: protein-coding gene | Cytoband: 10p14 | ||
| Entrez ID: 11164 | HGNC ID: HGNC:8052 | Ensembl Gene: ENSG00000165609 | OMIM ID: 609230 |
| Drug and gene relationship at DGIdb | |||
Expression of NUDT5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUDT5 | 11164 | 223100_s_at | 0.6365 | 0.1476 | |
| GSE26886 | NUDT5 | 11164 | 223100_s_at | 0.7295 | 0.0002 | |
| GSE45670 | NUDT5 | 11164 | 223100_s_at | 0.5910 | 0.0005 | |
| GSE53622 | NUDT5 | 11164 | 88182 | 0.3333 | 0.0001 | |
| GSE53624 | NUDT5 | 11164 | 88182 | 0.4973 | 0.0000 | |
| GSE63941 | NUDT5 | 11164 | 223100_s_at | 0.5471 | 0.1403 | |
| GSE77861 | NUDT5 | 11164 | 223100_s_at | 0.0486 | 0.8521 | |
| GSE97050 | NUDT5 | 11164 | A_23_P1199 | 0.8381 | 0.1003 | |
| SRP007169 | NUDT5 | 11164 | RNAseq | -0.2021 | 0.6194 | |
| SRP008496 | NUDT5 | 11164 | RNAseq | -0.2239 | 0.4480 | |
| SRP064894 | NUDT5 | 11164 | RNAseq | 0.3277 | 0.0365 | |
| SRP133303 | NUDT5 | 11164 | RNAseq | 0.0470 | 0.7550 | |
| SRP159526 | NUDT5 | 11164 | RNAseq | 0.1244 | 0.6877 | |
| SRP193095 | NUDT5 | 11164 | RNAseq | -0.1011 | 0.3748 | |
| SRP219564 | NUDT5 | 11164 | RNAseq | 0.0652 | 0.8495 | |
| TCGA | NUDT5 | 11164 | RNAseq | 0.3524 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUDT5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUDT5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUDT5 | 11164 | 6 | 7 | 17 | |
| GSE20123 | NUDT5 | 11164 | 6 | 6 | 18 | |
| GSE43470 | NUDT5 | 11164 | 3 | 5 | 35 | |
| GSE46452 | NUDT5 | 11164 | 2 | 14 | 43 | |
| GSE47630 | NUDT5 | 11164 | 6 | 14 | 20 | |
| GSE54993 | NUDT5 | 11164 | 11 | 0 | 59 | |
| GSE54994 | NUDT5 | 11164 | 4 | 10 | 39 | |
| GSE60625 | NUDT5 | 11164 | 0 | 0 | 11 | |
| GSE74703 | NUDT5 | 11164 | 2 | 3 | 31 | |
| GSE74704 | NUDT5 | 11164 | 1 | 5 | 14 | |
| TCGA | NUDT5 | 11164 | 20 | 24 | 52 |
Total number of gains: 61; Total number of losses: 88; Total Number of normals: 339.
Somatic mutations of NUDT5:
Generating mutation plots.
Highly correlated genes for NUDT5:
Showing top 20/1243 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUDT5 | CDC123 | 0.823908 | 8 | 0 | 8 |
| NUDT5 | MAP4K4 | 0.807759 | 3 | 0 | 3 |
| NUDT5 | TMF1 | 0.781451 | 3 | 0 | 3 |
| NUDT5 | LACTB | 0.774561 | 3 | 0 | 3 |
| NUDT5 | PRELID1 | 0.756741 | 3 | 0 | 3 |
| NUDT5 | PNO1 | 0.753754 | 4 | 0 | 4 |
| NUDT5 | ALKBH6 | 0.749166 | 3 | 0 | 3 |
| NUDT5 | TMEM132A | 0.742059 | 4 | 0 | 4 |
| NUDT5 | CCDC86 | 0.741959 | 4 | 0 | 4 |
| NUDT5 | RFWD3 | 0.741511 | 4 | 0 | 4 |
| NUDT5 | STEAP1B | 0.741491 | 4 | 0 | 4 |
| NUDT5 | OSBPL3 | 0.739831 | 3 | 0 | 3 |
| NUDT5 | GTF3C2 | 0.732867 | 3 | 0 | 3 |
| NUDT5 | VPS35 | 0.726341 | 3 | 0 | 3 |
| NUDT5 | RAD18 | 0.723888 | 3 | 0 | 3 |
| NUDT5 | CCT6A | 0.719909 | 5 | 0 | 4 |
| NUDT5 | TMEM223 | 0.716677 | 4 | 0 | 3 |
| NUDT5 | U2SURP | 0.715187 | 4 | 0 | 4 |
| NUDT5 | CARD10 | 0.713782 | 3 | 0 | 3 |
| NUDT5 | CSNK2A2 | 0.711208 | 3 | 0 | 3 |
For details and further investigation, click here
