POLR3GL

 

Full name: RNA polymerase III subunit G like Alias Symbol: flj32422|MGC3200
Type: protein-coding gene Cytoband: 1q21.1
Entrez ID: 84265 HGNC ID: HGNC:28466 Ensembl Gene: ENSG00000121851 OMIM ID: 617457
Drug and gene relationship at DGIdb

 

Expression of POLR3GL:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 POLR3GL 84265 223269_at -0.4249 0.3039
GSE26886 POLR3GL 84265 223269_at 0.0941 0.8482
GSE45670 POLR3GL 84265 223269_at -0.4595 0.0048
GSE53622 POLR3GL 84265 108400 -0.3322 0.0000
GSE53624 POLR3GL 84265 108400 -0.3217 0.0000
GSE63941 POLR3GL 84265 223269_at -1.0568 0.0204
GSE77861 POLR3GL 84265 223269_at -0.1579 0.4224
GSE97050 POLR3GL 84265 A_23_P23855 -0.2858 0.2579
SRP064894 POLR3GL 84265 RNAseq -0.0496 0.8081
SRP133303 POLR3GL 84265 RNAseq -0.1059 0.4463
SRP159526 POLR3GL 84265 RNAseq -0.0865 0.7232
SRP193095 POLR3GL 84265 RNAseq -0.4694 0.0001
SRP219564 POLR3GL 84265 RNAseq -0.1474 0.7289
TCGA POLR3GL 84265 RNAseq -0.3162 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by POLR3GL expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of POLR3GL:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 POLR3GL 84265 13 0 17
GSE20123 POLR3GL 84265 13 0 17
GSE43470 POLR3GL 84265 5 2 36
GSE46452 POLR3GL 84265 2 1 56
GSE47630 POLR3GL 84265 12 2 26
GSE54993 POLR3GL 84265 0 2 68
GSE54994 POLR3GL 84265 15 0 38
GSE60625 POLR3GL 84265 0 0 11
GSE74703 POLR3GL 84265 5 2 29
GSE74704 POLR3GL 84265 6 0 14
TCGA POLR3GL 84265 33 15 48

Total number of gains: 104; Total number of losses: 24; Total Number of normals: 360.  


 

Somatic mutations of POLR3GL:

 

Generating mutation plots.

 

Highly correlated genes for POLR3GL:

 

Showing top 20/927 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
POLR3GLMACROD20.806051303
POLR3GLAFF30.791531303
POLR3GLCBLL10.770659303
POLR3GLFBXL30.770026404
POLR3GLNPY1R0.769876303
POLR3GLEIF2D0.757031303
POLR3GLUBR30.752755303
POLR3GLSPOP0.745281404
POLR3GLRSRC20.741719403
POLR3GLTK20.734129303
POLR3GLSTUB10.727949303
POLR3GLDHRS70.727755303
POLR3GLTCF7L20.727561303
POLR3GLZNF1360.725034303
POLR3GLKLF90.720537505
POLR3GLSORCS10.720315505
POLR3GLFKBP70.720007303
POLR3GLUHRF20.719415303
POLR3GLTMOD10.714711303
POLR3GLC1QTNF70.713447505

For details and further investigation, click here