| Full name: RNA binding region (RNP1, RRM) containing 3 | Alias Symbol: KIAA1839|FLJ20008|RBM40|SNRNP65 | ||
| Type: protein-coding gene | Cytoband: 1p21.1 | ||
| Entrez ID: 55599 | HGNC ID: HGNC:18666 | Ensembl Gene: ENSG00000185946 | OMIM ID: 618016 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RNPC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNPC3 | 55599 | 229903_x_at | -0.4201 | 0.1236 | |
| GSE26886 | RNPC3 | 55599 | 229903_x_at | -0.6863 | 0.0203 | |
| GSE45670 | RNPC3 | 55599 | 229903_x_at | -0.2977 | 0.0373 | |
| GSE53622 | RNPC3 | 55599 | 95645 | -0.1124 | 0.2459 | |
| GSE53624 | RNPC3 | 55599 | 95645 | -0.1890 | 0.0350 | |
| GSE63941 | RNPC3 | 55599 | 229903_x_at | 0.0923 | 0.8492 | |
| GSE77861 | RNPC3 | 55599 | 229903_x_at | -0.1732 | 0.2801 | |
| GSE97050 | RNPC3 | 55599 | A_33_P3339066 | -0.5255 | 0.1028 | |
| SRP007169 | RNPC3 | 55599 | RNAseq | -0.4379 | 0.3953 | |
| SRP008496 | RNPC3 | 55599 | RNAseq | -0.2743 | 0.4719 | |
| SRP064894 | RNPC3 | 55599 | RNAseq | -0.6203 | 0.0673 | |
| SRP133303 | RNPC3 | 55599 | RNAseq | -0.6254 | 0.0000 | |
| SRP159526 | RNPC3 | 55599 | RNAseq | -0.8987 | 0.0017 | |
| SRP193095 | RNPC3 | 55599 | RNAseq | -0.4752 | 0.0004 | |
| SRP219564 | RNPC3 | 55599 | RNAseq | -0.7212 | 0.0952 | |
| TCGA | RNPC3 | 55599 | RNAseq | -0.2368 | 0.0012 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNPC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNPC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNPC3 | 55599 | 0 | 11 | 19 | |
| GSE20123 | RNPC3 | 55599 | 0 | 11 | 19 | |
| GSE43470 | RNPC3 | 55599 | 0 | 6 | 37 | |
| GSE46452 | RNPC3 | 55599 | 2 | 1 | 56 | |
| GSE47630 | RNPC3 | 55599 | 9 | 5 | 26 | |
| GSE54993 | RNPC3 | 55599 | 0 | 1 | 69 | |
| GSE54994 | RNPC3 | 55599 | 7 | 5 | 41 | |
| GSE60625 | RNPC3 | 55599 | 0 | 0 | 11 | |
| GSE74703 | RNPC3 | 55599 | 0 | 5 | 31 | |
| GSE74704 | RNPC3 | 55599 | 0 | 7 | 13 | |
| TCGA | RNPC3 | 55599 | 8 | 23 | 65 |
Total number of gains: 26; Total number of losses: 75; Total Number of normals: 387.
Somatic mutations of RNPC3:
Generating mutation plots.
Highly correlated genes for RNPC3:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNPC3 | RPL29 | 0.778898 | 3 | 0 | 3 |
| RNPC3 | OXCT1 | 0.765676 | 3 | 0 | 3 |
| RNPC3 | CBLL1 | 0.755159 | 3 | 0 | 3 |
| RNPC3 | RCHY1 | 0.75307 | 3 | 0 | 3 |
| RNPC3 | SUCLG2 | 0.748932 | 4 | 0 | 4 |
| RNPC3 | NTN4 | 0.748029 | 3 | 0 | 3 |
| RNPC3 | XPC | 0.746571 | 3 | 0 | 3 |
| RNPC3 | C1orf56 | 0.74304 | 3 | 0 | 3 |
| RNPC3 | HDHD2 | 0.742127 | 4 | 0 | 4 |
| RNPC3 | RASA2 | 0.740944 | 3 | 0 | 3 |
| RNPC3 | LRRFIP2 | 0.734418 | 3 | 0 | 3 |
| RNPC3 | MID2 | 0.727449 | 3 | 0 | 3 |
| RNPC3 | KIAA2026 | 0.723376 | 4 | 0 | 4 |
| RNPC3 | C12orf29 | 0.720342 | 4 | 0 | 3 |
| RNPC3 | REPS1 | 0.718876 | 3 | 0 | 3 |
| RNPC3 | PRELP | 0.716919 | 3 | 0 | 3 |
| RNPC3 | KLF4 | 0.715632 | 3 | 0 | 3 |
| RNPC3 | UNC5CL | 0.713791 | 3 | 0 | 3 |
| RNPC3 | FBXL3 | 0.711183 | 5 | 0 | 5 |
| RNPC3 | ATG2B | 0.707537 | 3 | 0 | 3 |
For details and further investigation, click here
