CCDC110

 

Full name: coiled-coil domain containing 110 Alias Symbol: KM-HN-1|MGC33607|CT52
Type: protein-coding gene Cytoband: 4q35.1
Entrez ID: 256309 HGNC ID: HGNC:28504 Ensembl Gene: ENSG00000168491 OMIM ID: 609488
Drug and gene relationship at DGIdb

 

Expression of CCDC110:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCDC110 256309 230900_at -0.5487 0.2838
GSE26886 CCDC110 256309 230900_at 0.1746 0.4407
GSE45670 CCDC110 256309 230900_at -0.9024 0.0000
GSE53622 CCDC110 256309 5657 -1.1987 0.0000
GSE53624 CCDC110 256309 5657 -1.2068 0.0000
GSE63941 CCDC110 256309 230900_at -0.0044 0.9885
GSE77861 CCDC110 256309 230900_at -0.0193 0.8586
SRP133303 CCDC110 256309 RNAseq -0.4623 0.2369
SRP159526 CCDC110 256309 RNAseq -0.1347 0.8062
TCGA CCDC110 256309 RNAseq -1.4959 0.0000

Upregulated datasets: 0; Downregulated datasets: 3.  


 

Survival by CCDC110 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CCDC110:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCDC110 256309 3 11 16
GSE20123 CCDC110 256309 3 11 16
GSE43470 CCDC110 256309 1 13 29
GSE46452 CCDC110 256309 1 36 22
GSE47630 CCDC110 256309 0 22 18
GSE54993 CCDC110 256309 10 0 60
GSE54994 CCDC110 256309 2 12 39
GSE60625 CCDC110 256309 0 0 11
GSE74703 CCDC110 256309 1 10 25
GSE74704 CCDC110 256309 1 5 14
TCGA CCDC110 256309 10 33 53

Total number of gains: 32; Total number of losses: 153; Total Number of normals: 303.  


 

Somatic mutations of CCDC110:

 

Generating mutation plots.

 

Highly correlated genes for CCDC110:

 

Showing top 20/498 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCDC110C1QTNF70.763112404
CCDC110ADH1B0.757413404
CCDC110PCMTD10.745115303
CCDC110PGM50.734149404
CCDC110IL17D0.728459303
CCDC110RERGL0.725231404
CCDC110NEGR10.721614404
CCDC110TMEM1000.721059404
CCDC110RBPMS20.716202404
CCDC110APOD0.714868404
CCDC110PTCHD10.713242505
CCDC110PABPC50.712746404
CCDC110DPT0.71145404
CCDC110LIFR0.709985404
CCDC110PBXIP10.70824404
CCDC110RNF1500.707851404
CCDC110NBEA0.707467403
CCDC110SLC8A10.707257303
CCDC110PDK40.707151404
CCDC110MGARP0.706503303

For details and further investigation, click here