| Full name: coiled-coil domain containing 115 | Alias Symbol: MGC12981|FLJ30131|ccp1 | ||
| Type: protein-coding gene | Cytoband: 2q21.1 | ||
| Entrez ID: 84317 | HGNC ID: HGNC:28178 | Ensembl Gene: ENSG00000136710 | OMIM ID: 613734 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CCDC115:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC115 | 84317 | 224946_s_at | 0.2420 | 0.5200 | |
| GSE26886 | CCDC115 | 84317 | 224946_s_at | -0.9171 | 0.0002 | |
| GSE45670 | CCDC115 | 84317 | 224946_s_at | -0.3256 | 0.0225 | |
| GSE53622 | CCDC115 | 84317 | 12664 | -0.0956 | 0.2434 | |
| GSE53624 | CCDC115 | 84317 | 12664 | -0.3332 | 0.0000 | |
| GSE63941 | CCDC115 | 84317 | 224946_s_at | 0.0357 | 0.9618 | |
| GSE77861 | CCDC115 | 84317 | 224946_s_at | -0.5143 | 0.0239 | |
| GSE97050 | CCDC115 | 84317 | A_23_P17074 | -0.0644 | 0.7597 | |
| SRP007169 | CCDC115 | 84317 | RNAseq | -1.2273 | 0.0043 | |
| SRP008496 | CCDC115 | 84317 | RNAseq | -0.9821 | 0.0000 | |
| SRP064894 | CCDC115 | 84317 | RNAseq | -0.5329 | 0.0003 | |
| SRP133303 | CCDC115 | 84317 | RNAseq | -0.4912 | 0.0011 | |
| SRP159526 | CCDC115 | 84317 | RNAseq | -0.1525 | 0.3726 | |
| SRP193095 | CCDC115 | 84317 | RNAseq | -0.6426 | 0.0000 | |
| SRP219564 | CCDC115 | 84317 | RNAseq | -0.5474 | 0.0614 | |
| TCGA | CCDC115 | 84317 | RNAseq | 0.0266 | 0.6289 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CCDC115 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC115:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC115 | 84317 | 5 | 3 | 22 | |
| GSE20123 | CCDC115 | 84317 | 5 | 3 | 22 | |
| GSE43470 | CCDC115 | 84317 | 2 | 2 | 39 | |
| GSE46452 | CCDC115 | 84317 | 1 | 3 | 55 | |
| GSE47630 | CCDC115 | 84317 | 5 | 0 | 35 | |
| GSE54993 | CCDC115 | 84317 | 0 | 6 | 64 | |
| GSE54994 | CCDC115 | 84317 | 11 | 0 | 42 | |
| GSE60625 | CCDC115 | 84317 | 0 | 3 | 8 | |
| GSE74703 | CCDC115 | 84317 | 2 | 1 | 33 | |
| GSE74704 | CCDC115 | 84317 | 3 | 1 | 16 | |
| TCGA | CCDC115 | 84317 | 22 | 9 | 65 |
Total number of gains: 56; Total number of losses: 31; Total Number of normals: 401.
Somatic mutations of CCDC115:
Generating mutation plots.
Highly correlated genes for CCDC115:
Showing top 20/473 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC115 | ITPRIPL2 | 0.741594 | 3 | 0 | 3 |
| CCDC115 | CMPK1 | 0.739557 | 3 | 0 | 3 |
| CCDC115 | RASSF9 | 0.737592 | 3 | 0 | 3 |
| CCDC115 | FDXACB1 | 0.721662 | 3 | 0 | 3 |
| CCDC115 | SH3PXD2A | 0.719453 | 3 | 0 | 3 |
| CCDC115 | CIPC | 0.71627 | 4 | 0 | 4 |
| CCDC115 | PPIP5K2 | 0.70987 | 4 | 0 | 4 |
| CCDC115 | ARFGAP2 | 0.70645 | 3 | 0 | 3 |
| CCDC115 | STK38 | 0.701255 | 4 | 0 | 4 |
| CCDC115 | TMBIM6 | 0.696954 | 3 | 0 | 3 |
| CCDC115 | RIOK3 | 0.696219 | 3 | 0 | 3 |
| CCDC115 | ECI2 | 0.680284 | 3 | 0 | 3 |
| CCDC115 | POGK | 0.67021 | 3 | 0 | 3 |
| CCDC115 | ZNF585A | 0.664889 | 3 | 0 | 3 |
| CCDC115 | CNST | 0.664584 | 3 | 0 | 3 |
| CCDC115 | ZDHHC21 | 0.660474 | 3 | 0 | 3 |
| CCDC115 | SREK1 | 0.658725 | 4 | 0 | 3 |
| CCDC115 | RCAN3 | 0.658229 | 5 | 0 | 4 |
| CCDC115 | DENND2C | 0.658151 | 3 | 0 | 3 |
| CCDC115 | HEBP2 | 0.65186 | 3 | 0 | 3 |
For details and further investigation, click here
