| Full name: transmembrane BAX inhibitor motif containing 6 | Alias Symbol: BI-1|BAXI1 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 7009 | HGNC ID: HGNC:11723 | Ensembl Gene: ENSG00000139644 | OMIM ID: 600748 |
| Drug and gene relationship at DGIdb | |||
Expression of TMBIM6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMBIM6 | 7009 | 200804_at | -0.0454 | 0.9460 | |
| GSE20347 | TMBIM6 | 7009 | 200803_s_at | -0.6224 | 0.0001 | |
| GSE23400 | TMBIM6 | 7009 | 200804_at | -0.2337 | 0.0016 | |
| GSE26886 | TMBIM6 | 7009 | 200804_at | -1.0130 | 0.0001 | |
| GSE29001 | TMBIM6 | 7009 | 200803_s_at | -0.4762 | 0.0824 | |
| GSE38129 | TMBIM6 | 7009 | 200803_s_at | -0.2154 | 0.2732 | |
| GSE45670 | TMBIM6 | 7009 | 200804_at | -0.2520 | 0.0396 | |
| GSE53622 | TMBIM6 | 7009 | 59446 | 0.1723 | 0.0293 | |
| GSE53624 | TMBIM6 | 7009 | 86183 | -0.4555 | 0.0000 | |
| GSE63941 | TMBIM6 | 7009 | 200803_s_at | 0.9338 | 0.0028 | |
| GSE77861 | TMBIM6 | 7009 | 200803_s_at | -0.4908 | 0.0862 | |
| GSE97050 | TMBIM6 | 7009 | A_23_P204702 | 0.0187 | 0.9730 | |
| SRP007169 | TMBIM6 | 7009 | RNAseq | -1.0870 | 0.0030 | |
| SRP008496 | TMBIM6 | 7009 | RNAseq | -1.0358 | 0.0000 | |
| SRP064894 | TMBIM6 | 7009 | RNAseq | -0.1325 | 0.3614 | |
| SRP133303 | TMBIM6 | 7009 | RNAseq | -0.0397 | 0.6870 | |
| SRP159526 | TMBIM6 | 7009 | RNAseq | -0.4246 | 0.0778 | |
| SRP193095 | TMBIM6 | 7009 | RNAseq | -0.6131 | 0.0000 | |
| SRP219564 | TMBIM6 | 7009 | RNAseq | -0.2957 | 0.1788 | |
| TCGA | TMBIM6 | 7009 | RNAseq | -0.1792 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TMBIM6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMBIM6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMBIM6 | 7009 | 7 | 1 | 22 | |
| GSE20123 | TMBIM6 | 7009 | 7 | 1 | 22 | |
| GSE43470 | TMBIM6 | 7009 | 3 | 0 | 40 | |
| GSE46452 | TMBIM6 | 7009 | 8 | 1 | 50 | |
| GSE47630 | TMBIM6 | 7009 | 11 | 2 | 27 | |
| GSE54993 | TMBIM6 | 7009 | 0 | 5 | 65 | |
| GSE54994 | TMBIM6 | 7009 | 4 | 1 | 48 | |
| GSE60625 | TMBIM6 | 7009 | 0 | 0 | 11 | |
| GSE74703 | TMBIM6 | 7009 | 3 | 0 | 33 | |
| GSE74704 | TMBIM6 | 7009 | 5 | 1 | 14 | |
| TCGA | TMBIM6 | 7009 | 16 | 11 | 69 |
Total number of gains: 64; Total number of losses: 23; Total Number of normals: 401.
Somatic mutations of TMBIM6:
Generating mutation plots.
Highly correlated genes for TMBIM6:
Showing top 20/969 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMBIM6 | PIK3CB | 0.794423 | 3 | 0 | 3 |
| TMBIM6 | ZNF616 | 0.761906 | 3 | 0 | 3 |
| TMBIM6 | GLUD1 | 0.760804 | 3 | 0 | 3 |
| TMBIM6 | PANK1 | 0.730009 | 3 | 0 | 3 |
| TMBIM6 | APOBR | 0.729005 | 3 | 0 | 3 |
| TMBIM6 | ASH2L | 0.716595 | 3 | 0 | 3 |
| TMBIM6 | ZNF92 | 0.712792 | 3 | 0 | 3 |
| TMBIM6 | CCDC85C | 0.705413 | 4 | 0 | 4 |
| TMBIM6 | HERPUD1 | 0.700954 | 4 | 0 | 3 |
| TMBIM6 | CCDC115 | 0.696954 | 3 | 0 | 3 |
| TMBIM6 | ITCH | 0.695375 | 7 | 0 | 7 |
| TMBIM6 | ZNF581 | 0.695087 | 3 | 0 | 3 |
| TMBIM6 | PARG | 0.693333 | 3 | 0 | 3 |
| TMBIM6 | PLEKHN1 | 0.692565 | 3 | 0 | 3 |
| TMBIM6 | NDFIP2 | 0.690973 | 3 | 0 | 3 |
| TMBIM6 | PRMT6 | 0.688051 | 3 | 0 | 3 |
| TMBIM6 | IRAK2 | 0.686136 | 3 | 0 | 3 |
| TMBIM6 | ZNF436 | 0.680119 | 5 | 0 | 5 |
| TMBIM6 | UCHL3 | 0.679211 | 3 | 0 | 3 |
| TMBIM6 | RPS3 | 0.678473 | 3 | 0 | 3 |
For details and further investigation, click here
