| Full name: RIO kinase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 18q11.2 | ||
| Entrez ID: 8780 | HGNC ID: HGNC:11451 | Ensembl Gene: ENSG00000101782 | OMIM ID: 603579 |
| Drug and gene relationship at DGIdb | |||
Expression of RIOK3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RIOK3 | 8780 | 202130_at | -1.1516 | 0.0297 | |
| GSE20347 | RIOK3 | 8780 | 202130_at | -1.1601 | 0.0000 | |
| GSE23400 | RIOK3 | 8780 | 202130_at | -0.7630 | 0.0000 | |
| GSE26886 | RIOK3 | 8780 | 202130_at | -1.9659 | 0.0000 | |
| GSE29001 | RIOK3 | 8780 | 202130_at | -1.2528 | 0.0030 | |
| GSE38129 | RIOK3 | 8780 | 202130_at | -0.6942 | 0.0020 | |
| GSE45670 | RIOK3 | 8780 | 202130_at | -0.5324 | 0.0166 | |
| GSE53622 | RIOK3 | 8780 | 101859 | -0.6428 | 0.0000 | |
| GSE53624 | RIOK3 | 8780 | 101859 | -0.8519 | 0.0000 | |
| GSE63941 | RIOK3 | 8780 | 202130_at | -0.1718 | 0.7138 | |
| GSE77861 | RIOK3 | 8780 | 202130_at | -0.6202 | 0.0266 | |
| GSE97050 | RIOK3 | 8780 | A_33_P3317850 | -0.2378 | 0.4929 | |
| SRP007169 | RIOK3 | 8780 | RNAseq | -1.5477 | 0.0023 | |
| SRP008496 | RIOK3 | 8780 | RNAseq | -1.7127 | 0.0000 | |
| SRP064894 | RIOK3 | 8780 | RNAseq | -2.0836 | 0.0000 | |
| SRP133303 | RIOK3 | 8780 | RNAseq | -1.0672 | 0.0000 | |
| SRP159526 | RIOK3 | 8780 | RNAseq | -1.8168 | 0.0000 | |
| SRP193095 | RIOK3 | 8780 | RNAseq | -1.7951 | 0.0000 | |
| SRP219564 | RIOK3 | 8780 | RNAseq | -1.7257 | 0.0041 | |
| TCGA | RIOK3 | 8780 | RNAseq | 0.0116 | 0.8584 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by RIOK3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RIOK3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RIOK3 | 8780 | 2 | 5 | 23 | |
| GSE20123 | RIOK3 | 8780 | 1 | 5 | 24 | |
| GSE43470 | RIOK3 | 8780 | 2 | 1 | 40 | |
| GSE46452 | RIOK3 | 8780 | 3 | 23 | 33 | |
| GSE47630 | RIOK3 | 8780 | 6 | 18 | 16 | |
| GSE54993 | RIOK3 | 8780 | 7 | 1 | 62 | |
| GSE54994 | RIOK3 | 8780 | 4 | 12 | 37 | |
| GSE60625 | RIOK3 | 8780 | 0 | 4 | 7 | |
| GSE74703 | RIOK3 | 8780 | 2 | 1 | 33 | |
| GSE74704 | RIOK3 | 8780 | 1 | 4 | 15 | |
| TCGA | RIOK3 | 8780 | 14 | 25 | 57 |
Total number of gains: 42; Total number of losses: 99; Total Number of normals: 347.
Somatic mutations of RIOK3:
Generating mutation plots.
Highly correlated genes for RIOK3:
Showing top 20/1630 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RIOK3 | SMIM5 | 0.817729 | 6 | 0 | 6 |
| RIOK3 | SFTA2 | 0.814061 | 4 | 0 | 4 |
| RIOK3 | PTK6 | 0.804706 | 10 | 0 | 10 |
| RIOK3 | FAM3D | 0.803038 | 7 | 0 | 7 |
| RIOK3 | KRT78 | 0.801902 | 7 | 0 | 7 |
| RIOK3 | BNIPL | 0.799745 | 7 | 0 | 7 |
| RIOK3 | CYSRT1 | 0.797778 | 6 | 0 | 6 |
| RIOK3 | EPS8L1 | 0.793616 | 11 | 0 | 11 |
| RIOK3 | CLIC3 | 0.793053 | 9 | 0 | 9 |
| RIOK3 | FCHO2 | 0.792948 | 6 | 0 | 6 |
| RIOK3 | C5orf66-AS1 | 0.786968 | 6 | 0 | 6 |
| RIOK3 | GYS2 | 0.786313 | 10 | 0 | 10 |
| RIOK3 | TP53I3 | 0.786174 | 11 | 0 | 11 |
| RIOK3 | C18orf25 | 0.78235 | 11 | 0 | 11 |
| RIOK3 | CAPN14 | 0.780302 | 6 | 0 | 6 |
| RIOK3 | IL1RN | 0.779821 | 10 | 0 | 10 |
| RIOK3 | CHP1 | 0.779184 | 10 | 0 | 10 |
| RIOK3 | HCG22 | 0.779132 | 6 | 0 | 6 |
| RIOK3 | TTC9 | 0.777919 | 11 | 0 | 11 |
| RIOK3 | CYP4F22 | 0.777815 | 3 | 0 | 3 |
For details and further investigation, click here
