| Full name: coiled-coil domain containing 146 | Alias Symbol: KIAA1505 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 57639 | HGNC ID: HGNC:29296 | Ensembl Gene: ENSG00000135205 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC146:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC146 | 57639 | 227091_at | -0.5579 | 0.2602 | |
| GSE26886 | CCDC146 | 57639 | 227091_at | 0.0778 | 0.8232 | |
| GSE45670 | CCDC146 | 57639 | 227091_at | -0.4223 | 0.2458 | |
| GSE53622 | CCDC146 | 57639 | 121531 | -0.5074 | 0.0000 | |
| GSE53624 | CCDC146 | 57639 | 121531 | -0.5610 | 0.0000 | |
| GSE63941 | CCDC146 | 57639 | 227091_at | -0.9901 | 0.2583 | |
| GSE77861 | CCDC146 | 57639 | 227091_at | -0.4518 | 0.0712 | |
| GSE97050 | CCDC146 | 57639 | A_23_P168771 | -0.1427 | 0.7963 | |
| SRP007169 | CCDC146 | 57639 | RNAseq | -0.6725 | 0.3120 | |
| SRP064894 | CCDC146 | 57639 | RNAseq | -0.7692 | 0.0076 | |
| SRP133303 | CCDC146 | 57639 | RNAseq | -0.4055 | 0.1537 | |
| SRP193095 | CCDC146 | 57639 | RNAseq | 0.2000 | 0.4073 | |
| SRP219564 | CCDC146 | 57639 | RNAseq | -0.7153 | 0.1249 | |
| TCGA | CCDC146 | 57639 | RNAseq | -0.1750 | 0.1869 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC146 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC146:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC146 | 57639 | 15 | 1 | 14 | |
| GSE20123 | CCDC146 | 57639 | 15 | 1 | 14 | |
| GSE43470 | CCDC146 | 57639 | 3 | 2 | 38 | |
| GSE46452 | CCDC146 | 57639 | 11 | 0 | 48 | |
| GSE47630 | CCDC146 | 57639 | 7 | 3 | 30 | |
| GSE54993 | CCDC146 | 57639 | 1 | 7 | 62 | |
| GSE54994 | CCDC146 | 57639 | 15 | 3 | 35 | |
| GSE60625 | CCDC146 | 57639 | 0 | 0 | 11 | |
| GSE74703 | CCDC146 | 57639 | 3 | 1 | 32 | |
| GSE74704 | CCDC146 | 57639 | 8 | 1 | 11 | |
| TCGA | CCDC146 | 57639 | 44 | 6 | 46 |
Total number of gains: 122; Total number of losses: 25; Total Number of normals: 341.
Somatic mutations of CCDC146:
Generating mutation plots.
Highly correlated genes for CCDC146:
Showing top 20/310 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC146 | MKLN1 | 0.763007 | 3 | 0 | 3 |
| CCDC146 | UPF3B | 0.762364 | 3 | 0 | 3 |
| CCDC146 | PLCE1 | 0.755985 | 3 | 0 | 3 |
| CCDC146 | GATAD1 | 0.740427 | 3 | 0 | 3 |
| CCDC146 | LSM11 | 0.733055 | 3 | 0 | 3 |
| CCDC146 | NFYB | 0.7311 | 3 | 0 | 3 |
| CCDC146 | UBE3A | 0.716479 | 3 | 0 | 3 |
| CCDC146 | PPARA | 0.712297 | 3 | 0 | 3 |
| CCDC146 | SLC2A12 | 0.709415 | 3 | 0 | 3 |
| CCDC146 | RPS24 | 0.708353 | 3 | 0 | 3 |
| CCDC146 | ZNF547 | 0.696164 | 3 | 0 | 3 |
| CCDC146 | CTR9 | 0.694441 | 3 | 0 | 3 |
| CCDC146 | FNBP1 | 0.692564 | 3 | 0 | 3 |
| CCDC146 | HNRNPH3 | 0.691324 | 3 | 0 | 3 |
| CCDC146 | ZNF655 | 0.689108 | 4 | 0 | 3 |
| CCDC146 | CFL2 | 0.688583 | 3 | 0 | 3 |
| CCDC146 | ID4 | 0.68815 | 3 | 0 | 3 |
| CCDC146 | FAN1 | 0.687247 | 3 | 0 | 3 |
| CCDC146 | FAM149A | 0.683205 | 4 | 0 | 4 |
| CCDC146 | NTN1 | 0.680835 | 4 | 0 | 4 |
For details and further investigation, click here
