| Full name: family with sequence similarity 149 member A | Alias Symbol: DKFZP564J102|MST119|MSTP119 | ||
| Type: protein-coding gene | Cytoband: 4q35.1 | ||
| Entrez ID: 25854 | HGNC ID: HGNC:24527 | Ensembl Gene: ENSG00000109794 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM149A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM149A | 25854 | 214890_s_at | -1.4053 | 0.1833 | |
| GSE20347 | FAM149A | 25854 | 214889_at | -0.6497 | 0.0002 | |
| GSE23400 | FAM149A | 25854 | 214889_at | -0.3856 | 0.0000 | |
| GSE26886 | FAM149A | 25854 | 214889_at | -0.2147 | 0.5288 | |
| GSE29001 | FAM149A | 25854 | 214889_at | -0.9889 | 0.0030 | |
| GSE38129 | FAM149A | 25854 | 214889_at | -1.0605 | 0.0001 | |
| GSE45670 | FAM149A | 25854 | 214889_at | -1.8319 | 0.0000 | |
| GSE53622 | FAM149A | 25854 | 37216 | -2.2705 | 0.0000 | |
| GSE53624 | FAM149A | 25854 | 37216 | -1.4392 | 0.0000 | |
| GSE63941 | FAM149A | 25854 | 214889_at | -1.0571 | 0.0301 | |
| GSE77861 | FAM149A | 25854 | 214890_s_at | -0.2362 | 0.4039 | |
| GSE97050 | FAM149A | 25854 | A_23_P416965 | -1.1076 | 0.1235 | |
| SRP007169 | FAM149A | 25854 | RNAseq | -2.6728 | 0.0003 | |
| SRP064894 | FAM149A | 25854 | RNAseq | -1.8712 | 0.0000 | |
| SRP133303 | FAM149A | 25854 | RNAseq | -0.7325 | 0.0000 | |
| SRP159526 | FAM149A | 25854 | RNAseq | -1.1449 | 0.0002 | |
| SRP193095 | FAM149A | 25854 | RNAseq | -0.4042 | 0.0400 | |
| SRP219564 | FAM149A | 25854 | RNAseq | -1.9191 | 0.0294 | |
| TCGA | FAM149A | 25854 | RNAseq | -1.4560 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by FAM149A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM149A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM149A | 25854 | 2 | 11 | 17 | |
| GSE20123 | FAM149A | 25854 | 2 | 11 | 17 | |
| GSE43470 | FAM149A | 25854 | 1 | 14 | 28 | |
| GSE46452 | FAM149A | 25854 | 1 | 36 | 22 | |
| GSE47630 | FAM149A | 25854 | 0 | 22 | 18 | |
| GSE54993 | FAM149A | 25854 | 10 | 0 | 60 | |
| GSE54994 | FAM149A | 25854 | 3 | 12 | 38 | |
| GSE60625 | FAM149A | 25854 | 0 | 0 | 11 | |
| GSE74703 | FAM149A | 25854 | 1 | 11 | 24 | |
| GSE74704 | FAM149A | 25854 | 1 | 5 | 14 | |
| TCGA | FAM149A | 25854 | 10 | 34 | 52 |
Total number of gains: 31; Total number of losses: 156; Total Number of normals: 301.
Somatic mutations of FAM149A:
Generating mutation plots.
Highly correlated genes for FAM149A:
Showing top 20/1332 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM149A | ATP1A2 | 0.790977 | 9 | 0 | 9 |
| FAM149A | CYP21A2 | 0.767757 | 3 | 0 | 3 |
| FAM149A | SORCS1 | 0.763507 | 4 | 0 | 4 |
| FAM149A | CLEC3B | 0.762447 | 3 | 0 | 3 |
| FAM149A | LRFN5 | 0.761976 | 4 | 0 | 4 |
| FAM149A | ANGPTL1 | 0.754607 | 6 | 0 | 6 |
| FAM149A | C7 | 0.752887 | 9 | 0 | 8 |
| FAM149A | SCN7A | 0.747982 | 9 | 0 | 9 |
| FAM149A | XKR4 | 0.745614 | 5 | 0 | 5 |
| FAM149A | C1QTNF7 | 0.744382 | 5 | 0 | 4 |
| FAM149A | APOD | 0.740072 | 8 | 0 | 8 |
| FAM149A | CASQ2 | 0.738313 | 10 | 0 | 9 |
| FAM149A | CHRDL1 | 0.735653 | 10 | 0 | 9 |
| FAM149A | TGFBR3 | 0.73499 | 9 | 0 | 9 |
| FAM149A | NR3C2 | 0.734024 | 10 | 0 | 10 |
| FAM149A | MAOB | 0.733065 | 10 | 0 | 9 |
| FAM149A | LMOD1 | 0.732958 | 11 | 0 | 9 |
| FAM149A | PPP1R9A | 0.732417 | 7 | 0 | 6 |
| FAM149A | ITGA7 | 0.730466 | 9 | 0 | 9 |
| FAM149A | SLIT3 | 0.730173 | 7 | 0 | 6 |
For details and further investigation, click here
