| Full name: coiled-coil domain containing 181 | Alias Symbol: FLJ25846 | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 57821 | HGNC ID: HGNC:28051 | Ensembl Gene: ENSG00000117477 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC181:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC181 | 57821 | 1555112_a_at | -0.2050 | 0.5413 | |
| GSE20347 | CCDC181 | 57821 | 206721_at | -0.0093 | 0.8789 | |
| GSE23400 | CCDC181 | 57821 | 206721_at | -0.0863 | 0.0001 | |
| GSE26886 | CCDC181 | 57821 | 1555112_a_at | -0.1663 | 0.1699 | |
| GSE29001 | CCDC181 | 57821 | 206721_at | 0.1723 | 0.5382 | |
| GSE38129 | CCDC181 | 57821 | 206721_at | -0.1399 | 0.1993 | |
| GSE45670 | CCDC181 | 57821 | 206721_at | -0.2165 | 0.1328 | |
| GSE53622 | CCDC181 | 57821 | 64804 | -0.9756 | 0.0000 | |
| GSE53624 | CCDC181 | 57821 | 64804 | -1.0317 | 0.0000 | |
| GSE63941 | CCDC181 | 57821 | 1555112_a_at | -0.1222 | 0.6277 | |
| GSE77861 | CCDC181 | 57821 | 206721_at | -0.0308 | 0.7588 | |
| SRP064894 | CCDC181 | 57821 | RNAseq | -0.1627 | 0.5349 | |
| SRP133303 | CCDC181 | 57821 | RNAseq | -0.2023 | 0.4194 | |
| SRP159526 | CCDC181 | 57821 | RNAseq | 0.7791 | 0.2335 | |
| SRP219564 | CCDC181 | 57821 | RNAseq | -0.2165 | 0.7167 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CCDC181 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CCDC181:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC181 | 57821 | 11 | 1 | 18 | |
| GSE20123 | CCDC181 | 57821 | 11 | 1 | 18 | |
| GSE43470 | CCDC181 | 57821 | 7 | 2 | 34 | |
| GSE46452 | CCDC181 | 57821 | 3 | 1 | 55 | |
| GSE47630 | CCDC181 | 57821 | 14 | 0 | 26 | |
| GSE54993 | CCDC181 | 57821 | 0 | 6 | 64 | |
| GSE54994 | CCDC181 | 57821 | 16 | 0 | 37 | |
| GSE60625 | CCDC181 | 57821 | 0 | 0 | 11 | |
| GSE74703 | CCDC181 | 57821 | 7 | 2 | 27 | |
| GSE74704 | CCDC181 | 57821 | 5 | 0 | 15 | |
| TCGA | CCDC181 | 57821 | 43 | 3 | 50 |
Total number of gains: 117; Total number of losses: 16; Total Number of normals: 355.
Somatic mutations of CCDC181:
Generating mutation plots.
Highly correlated genes for CCDC181:
Showing top 20/284 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC181 | PRR26 | 0.707689 | 3 | 0 | 3 |
| CCDC181 | GKAP1 | 0.691171 | 4 | 0 | 4 |
| CCDC181 | KLHL41 | 0.690792 | 3 | 0 | 3 |
| CCDC181 | CHD5 | 0.683675 | 3 | 0 | 3 |
| CCDC181 | NRXN1 | 0.680991 | 6 | 0 | 6 |
| CCDC181 | SLC35F1 | 0.672654 | 4 | 0 | 4 |
| CCDC181 | LRRC4C | 0.665681 | 3 | 0 | 3 |
| CCDC181 | CACNA2D2 | 0.660568 | 7 | 0 | 7 |
| CCDC181 | KIF5C | 0.656798 | 7 | 0 | 7 |
| CCDC181 | CCDC149 | 0.654801 | 3 | 0 | 3 |
| CCDC181 | ARHGEF40 | 0.65433 | 3 | 0 | 3 |
| CCDC181 | LRRTM1 | 0.652157 | 3 | 0 | 3 |
| CCDC181 | FAM184A | 0.650232 | 7 | 0 | 7 |
| CCDC181 | PI16 | 0.645436 | 3 | 0 | 3 |
| CCDC181 | LINC01354 | 0.644127 | 3 | 0 | 3 |
| CCDC181 | CORO2B | 0.638742 | 7 | 0 | 6 |
| CCDC181 | STX8 | 0.636244 | 3 | 0 | 3 |
| CCDC181 | VASH2 | 0.635225 | 5 | 0 | 4 |
| CCDC181 | SORCS1 | 0.633992 | 3 | 0 | 3 |
| CCDC181 | BNC2 | 0.62042 | 5 | 0 | 4 |
For details and further investigation, click here
