| Full name: syntaxin 8 | Alias Symbol: CARB | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 9482 | HGNC ID: HGNC:11443 | Ensembl Gene: ENSG00000170310 | OMIM ID: 604203 |
| Drug and gene relationship at DGIdb | |||
Expression of STX8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX8 | 9482 | 204690_at | -0.3262 | 0.3851 | |
| GSE20347 | STX8 | 9482 | 204690_at | -0.2669 | 0.0669 | |
| GSE23400 | STX8 | 9482 | 204690_at | 0.0102 | 0.8976 | |
| GSE26886 | STX8 | 9482 | 204690_at | 0.3750 | 0.0788 | |
| GSE29001 | STX8 | 9482 | 204690_at | -0.2426 | 0.1674 | |
| GSE38129 | STX8 | 9482 | 204690_at | -0.3124 | 0.0155 | |
| GSE45670 | STX8 | 9482 | 204690_at | -0.0682 | 0.7098 | |
| GSE53622 | STX8 | 9482 | 73035 | -0.0406 | 0.3822 | |
| GSE53624 | STX8 | 9482 | 73035 | -0.0774 | 0.0626 | |
| GSE63941 | STX8 | 9482 | 204690_at | -0.1459 | 0.7318 | |
| GSE77861 | STX8 | 9482 | 204690_at | 0.0794 | 0.8310 | |
| GSE97050 | STX8 | 9482 | A_23_P146908 | -0.0354 | 0.8965 | |
| SRP007169 | STX8 | 9482 | RNAseq | -0.9984 | 0.0147 | |
| SRP008496 | STX8 | 9482 | RNAseq | -0.8040 | 0.0064 | |
| SRP064894 | STX8 | 9482 | RNAseq | 0.5447 | 0.0825 | |
| SRP133303 | STX8 | 9482 | RNAseq | -0.0556 | 0.7228 | |
| SRP159526 | STX8 | 9482 | RNAseq | -0.0399 | 0.8340 | |
| SRP193095 | STX8 | 9482 | RNAseq | -0.3025 | 0.0041 | |
| SRP219564 | STX8 | 9482 | RNAseq | -0.2651 | 0.4740 | |
| TCGA | STX8 | 9482 | RNAseq | -0.0591 | 0.3617 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STX8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX8 | 9482 | 3 | 3 | 24 | |
| GSE20123 | STX8 | 9482 | 3 | 4 | 23 | |
| GSE43470 | STX8 | 9482 | 2 | 6 | 35 | |
| GSE46452 | STX8 | 9482 | 34 | 1 | 24 | |
| GSE47630 | STX8 | 9482 | 7 | 1 | 32 | |
| GSE54993 | STX8 | 9482 | 4 | 3 | 63 | |
| GSE54994 | STX8 | 9482 | 5 | 8 | 40 | |
| GSE60625 | STX8 | 9482 | 4 | 0 | 7 | |
| GSE74703 | STX8 | 9482 | 2 | 3 | 31 | |
| GSE74704 | STX8 | 9482 | 1 | 2 | 17 | |
| TCGA | STX8 | 9482 | 17 | 22 | 57 |
Total number of gains: 82; Total number of losses: 53; Total Number of normals: 353.
Somatic mutations of STX8:
Generating mutation plots.
Highly correlated genes for STX8:
Showing top 20/302 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX8 | SLC16A4 | 0.704563 | 3 | 0 | 3 |
| STX8 | DOCK3 | 0.701481 | 3 | 0 | 3 |
| STX8 | MLLT10 | 0.696982 | 3 | 0 | 3 |
| STX8 | EPHA3 | 0.693181 | 3 | 0 | 3 |
| STX8 | NLGN1 | 0.690146 | 3 | 0 | 3 |
| STX8 | TRIM3 | 0.688845 | 3 | 0 | 3 |
| STX8 | GRK5 | 0.684966 | 3 | 0 | 3 |
| STX8 | TTLL7 | 0.676509 | 4 | 0 | 4 |
| STX8 | PRELP | 0.675958 | 3 | 0 | 3 |
| STX8 | CDKN1C | 0.665299 | 3 | 0 | 3 |
| STX8 | PCDH9 | 0.661914 | 4 | 0 | 3 |
| STX8 | ANGPTL7 | 0.65861 | 4 | 0 | 3 |
| STX8 | LIX1L | 0.656087 | 3 | 0 | 3 |
| STX8 | POPDC2 | 0.650258 | 5 | 0 | 4 |
| STX8 | EMCN | 0.649053 | 3 | 0 | 3 |
| STX8 | PDGFRL | 0.643901 | 3 | 0 | 3 |
| STX8 | OMD | 0.642373 | 4 | 0 | 3 |
| STX8 | ZNF189 | 0.640124 | 3 | 0 | 3 |
| STX8 | DDIT3 | 0.639504 | 4 | 0 | 3 |
| STX8 | TPCN2 | 0.639015 | 3 | 0 | 3 |
For details and further investigation, click here
