| Full name: basonuclin 2 | Alias Symbol: BSN2|FLJ20043 | ||
| Type: protein-coding gene | Cytoband: 9p22.3-p22.2 | ||
| Entrez ID: 54796 | HGNC ID: HGNC:30988 | Ensembl Gene: ENSG00000173068 | OMIM ID: 608669 |
| Drug and gene relationship at DGIdb | |||
Expression of BNC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BNC2 | 54796 | 238478_at | -1.0443 | 0.1802 | |
| GSE20347 | BNC2 | 54796 | 220272_at | -0.1768 | 0.3658 | |
| GSE23400 | BNC2 | 54796 | 220272_at | -0.0885 | 0.4105 | |
| GSE26886 | BNC2 | 54796 | 230722_at | 0.4331 | 0.1637 | |
| GSE29001 | BNC2 | 54796 | 220272_at | -0.2209 | 0.5078 | |
| GSE38129 | BNC2 | 54796 | 220272_at | -0.4913 | 0.0699 | |
| GSE45670 | BNC2 | 54796 | 230722_at | -2.0707 | 0.0000 | |
| GSE53622 | BNC2 | 54796 | 83383 | -2.6326 | 0.0000 | |
| GSE53624 | BNC2 | 54796 | 83383 | -1.9979 | 0.0000 | |
| GSE63941 | BNC2 | 54796 | 230722_at | -4.5059 | 0.0000 | |
| GSE77861 | BNC2 | 54796 | 220272_at | -0.0825 | 0.7324 | |
| GSE97050 | BNC2 | 54796 | A_23_P43690 | -1.7894 | 0.0871 | |
| SRP007169 | BNC2 | 54796 | RNAseq | 1.3148 | 0.0079 | |
| SRP008496 | BNC2 | 54796 | RNAseq | 1.6875 | 0.0001 | |
| SRP064894 | BNC2 | 54796 | RNAseq | 0.3169 | 0.4014 | |
| SRP133303 | BNC2 | 54796 | RNAseq | -0.1162 | 0.7600 | |
| SRP159526 | BNC2 | 54796 | RNAseq | -1.2122 | 0.0008 | |
| SRP193095 | BNC2 | 54796 | RNAseq | 0.1779 | 0.4941 | |
| SRP219564 | BNC2 | 54796 | RNAseq | 0.0060 | 0.9936 | |
| TCGA | BNC2 | 54796 | RNAseq | -0.4041 | 0.0248 |
Upregulated datasets: 2; Downregulated datasets: 5.
Survival by BNC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BNC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BNC2 | 54796 | 2 | 16 | 12 | |
| GSE20123 | BNC2 | 54796 | 2 | 16 | 12 | |
| GSE43470 | BNC2 | 54796 | 4 | 11 | 28 | |
| GSE46452 | BNC2 | 54796 | 2 | 23 | 34 | |
| GSE47630 | BNC2 | 54796 | 4 | 26 | 10 | |
| GSE54993 | BNC2 | 54796 | 6 | 3 | 61 | |
| GSE54994 | BNC2 | 54796 | 10 | 16 | 27 | |
| GSE60625 | BNC2 | 54796 | 0 | 0 | 11 | |
| GSE74703 | BNC2 | 54796 | 4 | 8 | 24 | |
| GSE74704 | BNC2 | 54796 | 0 | 13 | 7 | |
| TCGA | BNC2 | 54796 | 14 | 50 | 32 |
Total number of gains: 48; Total number of losses: 182; Total Number of normals: 258.
Somatic mutations of BNC2:
Generating mutation plots.
Highly correlated genes for BNC2:
Showing top 20/1293 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BNC2 | AFF3 | 0.864083 | 3 | 0 | 3 |
| BNC2 | MRVI1 | 0.834939 | 7 | 0 | 7 |
| BNC2 | NEGR1 | 0.834419 | 6 | 0 | 6 |
| BNC2 | MAGI2-AS3 | 0.833713 | 6 | 0 | 6 |
| BNC2 | ANGPTL1 | 0.815796 | 6 | 0 | 6 |
| BNC2 | FAM13C | 0.813621 | 4 | 0 | 4 |
| BNC2 | LINC01279 | 0.805447 | 4 | 0 | 4 |
| BNC2 | TBX5 | 0.79634 | 7 | 0 | 7 |
| BNC2 | CYP21A2 | 0.790178 | 3 | 0 | 3 |
| BNC2 | RUNX1T1 | 0.784052 | 8 | 0 | 7 |
| BNC2 | SLITRK3 | 0.782895 | 7 | 0 | 7 |
| BNC2 | CLEC3B | 0.781906 | 3 | 0 | 3 |
| BNC2 | RSPO2 | 0.777007 | 3 | 0 | 3 |
| BNC2 | RNF150 | 0.773079 | 8 | 0 | 8 |
| BNC2 | DDR2 | 0.77139 | 12 | 0 | 12 |
| BNC2 | LRRK2 | 0.764483 | 6 | 0 | 6 |
| BNC2 | ANO5 | 0.764281 | 6 | 0 | 6 |
| BNC2 | ADAMTS8 | 0.762021 | 7 | 0 | 7 |
| BNC2 | C3orf70 | 0.761518 | 6 | 0 | 6 |
| BNC2 | FIBIN | 0.760669 | 5 | 0 | 4 |
For details and further investigation, click here
