SLC25A12

 

Full name: solute carrier family 25 member 12 Alias Symbol: Aralar
Type: protein-coding gene Cytoband: 2q31.1
Entrez ID: 8604 HGNC ID: HGNC:10982 Ensembl Gene: ENSG00000115840 OMIM ID: 603667
Drug and gene relationship at DGIdb

 

Expression of SLC25A12:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC25A12 8604 203340_s_at -0.0180 0.9826
GSE20347 SLC25A12 8604 203340_s_at 0.4747 0.0001
GSE23400 SLC25A12 8604 203340_s_at 0.1403 0.0884
GSE26886 SLC25A12 8604 203339_at 0.4228 0.0431
GSE29001 SLC25A12 8604 203339_at 0.1394 0.7519
GSE38129 SLC25A12 8604 203340_s_at 0.2746 0.0796
GSE45670 SLC25A12 8604 203340_s_at -0.0704 0.6998
GSE53622 SLC25A12 8604 6276 -0.1447 0.1128
GSE53624 SLC25A12 8604 6276 0.1255 0.2003
GSE63941 SLC25A12 8604 203340_s_at 0.3938 0.2630
GSE77861 SLC25A12 8604 203340_s_at 0.2566 0.2331
GSE97050 SLC25A12 8604 A_23_P142714 -0.4035 0.2513
SRP007169 SLC25A12 8604 RNAseq 0.2166 0.5789
SRP008496 SLC25A12 8604 RNAseq 0.3448 0.1922
SRP064894 SLC25A12 8604 RNAseq -0.1466 0.3384
SRP133303 SLC25A12 8604 RNAseq -0.0360 0.7968
SRP159526 SLC25A12 8604 RNAseq -0.1753 0.3748
SRP193095 SLC25A12 8604 RNAseq 0.0590 0.6541
SRP219564 SLC25A12 8604 RNAseq -0.0194 0.9686
TCGA SLC25A12 8604 RNAseq -0.1182 0.0430

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by SLC25A12 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SLC25A12:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC25A12 8604 8 0 22
GSE20123 SLC25A12 8604 8 0 22
GSE43470 SLC25A12 8604 6 1 36
GSE46452 SLC25A12 8604 1 4 54
GSE47630 SLC25A12 8604 5 3 32
GSE54993 SLC25A12 8604 0 5 65
GSE54994 SLC25A12 8604 11 3 39
GSE60625 SLC25A12 8604 0 3 8
GSE74703 SLC25A12 8604 5 1 30
GSE74704 SLC25A12 8604 5 0 15
TCGA SLC25A12 8604 28 6 62

Total number of gains: 77; Total number of losses: 26; Total Number of normals: 385.  

 

Somatic mutations of SLC25A12:

 

Generating mutation plots.

 

Highly correlated genes for SLC25A12:

 

Showing top 20/453 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC25A12DNAJC180.739619303
SLC25A12NPHP30.72882303
SLC25A12CD440.720477303
SLC25A12FMR10.713166303
SLC25A12MOB3C0.702838303
SLC25A12CRYBA10.695598303
SLC25A12NCF20.69247303
SLC25A12SNX130.685951303
SLC25A12CCDC500.682399303
SLC25A12CC2D2A0.680086403
SLC25A12C1orf1120.679582303
SLC25A12PALB20.678053303
SLC25A12KIF5B0.673094403
SLC25A12USP340.672661303
SLC25A12ABI20.672364403
SLC25A12ADO0.671722303
SLC25A12STRAP0.67068404
SLC25A12SRSF110.668458303
SLC25A12PFKM0.667567907
SLC25A12AMMECR1L0.659805404

For details and further investigation, click here