| Full name: sideroflexin 3 | Alias Symbol: SFX3|SLC56A3 | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 81855 | HGNC ID: HGNC:16087 | Ensembl Gene: ENSG00000107819 | OMIM ID: 615571 |
| Drug and gene relationship at DGIdb | |||
Expression of SFXN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFXN3 | 81855 | 220974_x_at | 0.4154 | 0.3845 | |
| GSE20347 | SFXN3 | 81855 | 220974_x_at | 0.7355 | 0.0000 | |
| GSE23400 | SFXN3 | 81855 | 220974_x_at | 0.3799 | 0.0000 | |
| GSE26886 | SFXN3 | 81855 | 220974_x_at | 1.2222 | 0.0000 | |
| GSE29001 | SFXN3 | 81855 | 220974_x_at | 0.4870 | 0.1006 | |
| GSE38129 | SFXN3 | 81855 | 220974_x_at | 0.4881 | 0.0291 | |
| GSE45670 | SFXN3 | 81855 | 220974_x_at | 0.3084 | 0.2386 | |
| GSE53622 | SFXN3 | 81855 | 102211 | -1.4752 | 0.0000 | |
| GSE53624 | SFXN3 | 81855 | 102211 | -1.9431 | 0.0000 | |
| GSE63941 | SFXN3 | 81855 | 220974_x_at | -1.1616 | 0.1271 | |
| GSE77861 | SFXN3 | 81855 | 220974_x_at | 0.6315 | 0.0586 | |
| GSE97050 | SFXN3 | 81855 | A_23_P202138 | -1.0039 | 0.1581 | |
| SRP007169 | SFXN3 | 81855 | RNAseq | 1.5096 | 0.0055 | |
| SRP008496 | SFXN3 | 81855 | RNAseq | 1.6866 | 0.0000 | |
| SRP064894 | SFXN3 | 81855 | RNAseq | 1.0862 | 0.0000 | |
| SRP133303 | SFXN3 | 81855 | RNAseq | 0.8483 | 0.0002 | |
| SRP159526 | SFXN3 | 81855 | RNAseq | 0.4124 | 0.1104 | |
| SRP193095 | SFXN3 | 81855 | RNAseq | 1.0685 | 0.0000 | |
| SRP219564 | SFXN3 | 81855 | RNAseq | 0.9810 | 0.0133 | |
| TCGA | SFXN3 | 81855 | RNAseq | -0.0001 | 0.9987 |
Upregulated datasets: 5; Downregulated datasets: 2.
Survival by SFXN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFXN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFXN3 | 81855 | 1 | 8 | 21 | |
| GSE20123 | SFXN3 | 81855 | 1 | 7 | 22 | |
| GSE43470 | SFXN3 | 81855 | 0 | 8 | 35 | |
| GSE46452 | SFXN3 | 81855 | 0 | 11 | 48 | |
| GSE47630 | SFXN3 | 81855 | 2 | 14 | 24 | |
| GSE54993 | SFXN3 | 81855 | 8 | 0 | 62 | |
| GSE54994 | SFXN3 | 81855 | 1 | 12 | 40 | |
| GSE60625 | SFXN3 | 81855 | 0 | 0 | 11 | |
| GSE74703 | SFXN3 | 81855 | 0 | 5 | 31 | |
| GSE74704 | SFXN3 | 81855 | 0 | 4 | 16 | |
| TCGA | SFXN3 | 81855 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.
Somatic mutations of SFXN3:
Generating mutation plots.
Highly correlated genes for SFXN3:
Showing top 20/327 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFXN3 | EPGN | 0.799021 | 3 | 0 | 3 |
| SFXN3 | NCCRP1 | 0.744988 | 3 | 0 | 3 |
| SFXN3 | UPK3B | 0.729586 | 3 | 0 | 3 |
| SFXN3 | C3orf20 | 0.716766 | 4 | 0 | 3 |
| SFXN3 | TRMT61A | 0.714805 | 3 | 0 | 3 |
| SFXN3 | KPRP | 0.699444 | 3 | 0 | 3 |
| SFXN3 | FSTL3 | 0.698844 | 9 | 0 | 9 |
| SFXN3 | ADAMTS15 | 0.694507 | 3 | 0 | 3 |
| SFXN3 | RILPL1 | 0.692708 | 3 | 0 | 3 |
| SFXN3 | PHF12 | 0.689451 | 5 | 0 | 4 |
| SFXN3 | DOCK11 | 0.687047 | 4 | 0 | 3 |
| SFXN3 | CCDC50 | 0.686697 | 6 | 0 | 6 |
| SFXN3 | CD276 | 0.686589 | 5 | 0 | 4 |
| SFXN3 | SNAI2 | 0.683919 | 7 | 0 | 7 |
| SFXN3 | TMPRSS11A | 0.683547 | 3 | 0 | 3 |
| SFXN3 | GNB1 | 0.682496 | 3 | 0 | 3 |
| SFXN3 | ZNF580 | 0.679313 | 3 | 0 | 3 |
| SFXN3 | DVL2 | 0.676737 | 4 | 0 | 3 |
| SFXN3 | RUNX1-IT1 | 0.673057 | 7 | 0 | 6 |
| SFXN3 | KRTCAP2 | 0.672027 | 3 | 0 | 3 |
For details and further investigation, click here
