| Full name: CD109 molecule | Alias Symbol: FLJ38569|DKFZp762L1111|CPAMD7 | ||
| Type: protein-coding gene | Cytoband: 6q13 | ||
| Entrez ID: 135228 | HGNC ID: HGNC:21685 | Ensembl Gene: ENSG00000156535 | OMIM ID: 608859 |
| Drug and gene relationship at DGIdb | |||
Expression of CD109:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD109 | 135228 | 226545_at | -0.2722 | 0.6379 | |
| GSE26886 | CD109 | 135228 | 226545_at | 0.5500 | 0.1077 | |
| GSE45670 | CD109 | 135228 | 226545_at | 0.2800 | 0.2182 | |
| GSE53622 | CD109 | 135228 | 30305 | 0.4096 | 0.0002 | |
| GSE53624 | CD109 | 135228 | 30305 | 0.5643 | 0.0000 | |
| GSE63941 | CD109 | 135228 | 226545_at | -1.5913 | 0.0375 | |
| GSE77861 | CD109 | 135228 | 226545_at | 0.8270 | 0.1922 | |
| GSE97050 | CD109 | 135228 | A_23_P331928 | 0.2277 | 0.4701 | |
| SRP007169 | CD109 | 135228 | RNAseq | 1.6038 | 0.0000 | |
| SRP008496 | CD109 | 135228 | RNAseq | 1.4880 | 0.0000 | |
| SRP064894 | CD109 | 135228 | RNAseq | 0.9505 | 0.0023 | |
| SRP133303 | CD109 | 135228 | RNAseq | 1.1416 | 0.0000 | |
| SRP159526 | CD109 | 135228 | RNAseq | 0.5238 | 0.1966 | |
| SRP193095 | CD109 | 135228 | RNAseq | 0.6964 | 0.0290 | |
| SRP219564 | CD109 | 135228 | RNAseq | 0.9556 | 0.1941 | |
| TCGA | CD109 | 135228 | RNAseq | 0.6567 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by CD109 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD109:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD109 | 135228 | 1 | 3 | 26 | |
| GSE20123 | CD109 | 135228 | 1 | 2 | 27 | |
| GSE43470 | CD109 | 135228 | 3 | 0 | 40 | |
| GSE46452 | CD109 | 135228 | 2 | 11 | 46 | |
| GSE47630 | CD109 | 135228 | 8 | 4 | 28 | |
| GSE54993 | CD109 | 135228 | 3 | 2 | 65 | |
| GSE54994 | CD109 | 135228 | 9 | 8 | 36 | |
| GSE60625 | CD109 | 135228 | 0 | 1 | 10 | |
| GSE74703 | CD109 | 135228 | 3 | 0 | 33 | |
| GSE74704 | CD109 | 135228 | 0 | 1 | 19 | |
| TCGA | CD109 | 135228 | 10 | 20 | 66 |
Total number of gains: 40; Total number of losses: 52; Total Number of normals: 396.
Somatic mutations of CD109:
Generating mutation plots.
Highly correlated genes for CD109:
Showing top 20/243 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD109 | DNMBP | 0.781191 | 3 | 0 | 3 |
| CD109 | SEC11A | 0.761977 | 3 | 0 | 3 |
| CD109 | PLEKHA8 | 0.751915 | 3 | 0 | 3 |
| CD109 | ABHD2 | 0.744136 | 3 | 0 | 3 |
| CD109 | KIAA0895L | 0.743641 | 3 | 0 | 3 |
| CD109 | DHRS7 | 0.736439 | 3 | 0 | 3 |
| CD109 | USP40 | 0.733058 | 3 | 0 | 3 |
| CD109 | SLC9A6 | 0.732074 | 3 | 0 | 3 |
| CD109 | PCSK5 | 0.727791 | 3 | 0 | 3 |
| CD109 | GNB1 | 0.721701 | 3 | 0 | 3 |
| CD109 | KREMEN1 | 0.71881 | 3 | 0 | 3 |
| CD109 | GLCE | 0.714953 | 3 | 0 | 3 |
| CD109 | BORA | 0.714899 | 3 | 0 | 3 |
| CD109 | PPP3CC | 0.714577 | 3 | 0 | 3 |
| CD109 | TNFAIP2 | 0.70713 | 3 | 0 | 3 |
| CD109 | NCAPG | 0.706731 | 3 | 0 | 3 |
| CD109 | SEL1L3 | 0.702648 | 4 | 0 | 4 |
| CD109 | C20orf194 | 0.700639 | 3 | 0 | 3 |
| CD109 | TK2 | 0.700314 | 3 | 0 | 3 |
| CD109 | S100PBP | 0.698087 | 3 | 0 | 3 |
For details and further investigation, click here
