| Full name: TNF alpha induced protein 2 | Alias Symbol: B94|EXOC3L3 | ||
| Type: protein-coding gene | Cytoband: 14q32 | ||
| Entrez ID: 7127 | HGNC ID: HGNC:11895 | Ensembl Gene: ENSG00000185215 | OMIM ID: 603300 |
| Drug and gene relationship at DGIdb | |||
Expression of TNFAIP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFAIP2 | 7127 | 202510_s_at | 0.0476 | 0.9735 | |
| GSE20347 | TNFAIP2 | 7127 | 202510_s_at | -0.0037 | 0.9939 | |
| GSE23400 | TNFAIP2 | 7127 | 202510_s_at | -0.0976 | 0.4228 | |
| GSE26886 | TNFAIP2 | 7127 | 202510_s_at | -0.2759 | 0.3512 | |
| GSE29001 | TNFAIP2 | 7127 | 202510_s_at | -0.3168 | 0.3608 | |
| GSE38129 | TNFAIP2 | 7127 | 202510_s_at | 0.1004 | 0.7368 | |
| GSE45670 | TNFAIP2 | 7127 | 202510_s_at | 0.3752 | 0.1293 | |
| GSE53622 | TNFAIP2 | 7127 | 91186 | 0.3250 | 0.0110 | |
| GSE53624 | TNFAIP2 | 7127 | 91186 | 0.0067 | 0.9453 | |
| GSE63941 | TNFAIP2 | 7127 | 202510_s_at | 1.6231 | 0.2325 | |
| GSE77861 | TNFAIP2 | 7127 | 202510_s_at | 0.5413 | 0.0951 | |
| GSE97050 | TNFAIP2 | 7127 | A_23_P421423 | 0.1131 | 0.7646 | |
| SRP007169 | TNFAIP2 | 7127 | RNAseq | 0.2714 | 0.5942 | |
| SRP008496 | TNFAIP2 | 7127 | RNAseq | 0.3004 | 0.4360 | |
| SRP064894 | TNFAIP2 | 7127 | RNAseq | -0.4842 | 0.1445 | |
| SRP133303 | TNFAIP2 | 7127 | RNAseq | -0.2274 | 0.3816 | |
| SRP159526 | TNFAIP2 | 7127 | RNAseq | 1.0731 | 0.0114 | |
| SRP193095 | TNFAIP2 | 7127 | RNAseq | 0.7010 | 0.0045 | |
| SRP219564 | TNFAIP2 | 7127 | RNAseq | 0.3237 | 0.3629 | |
| TCGA | TNFAIP2 | 7127 | RNAseq | 0.3441 | 0.0007 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TNFAIP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNFAIP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFAIP2 | 7127 | 12 | 4 | 14 | |
| GSE20123 | TNFAIP2 | 7127 | 11 | 3 | 16 | |
| GSE43470 | TNFAIP2 | 7127 | 6 | 4 | 33 | |
| GSE46452 | TNFAIP2 | 7127 | 18 | 4 | 37 | |
| GSE47630 | TNFAIP2 | 7127 | 10 | 8 | 22 | |
| GSE54993 | TNFAIP2 | 7127 | 3 | 8 | 59 | |
| GSE54994 | TNFAIP2 | 7127 | 21 | 4 | 28 | |
| GSE60625 | TNFAIP2 | 7127 | 0 | 2 | 9 | |
| GSE74703 | TNFAIP2 | 7127 | 5 | 3 | 28 | |
| GSE74704 | TNFAIP2 | 7127 | 5 | 3 | 12 | |
| TCGA | TNFAIP2 | 7127 | 32 | 20 | 44 |
Total number of gains: 123; Total number of losses: 63; Total Number of normals: 302.
Somatic mutations of TNFAIP2:
Generating mutation plots.
Highly correlated genes for TNFAIP2:
Showing top 20/118 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFAIP2 | KREMEN1 | 0.783435 | 3 | 0 | 3 |
| TNFAIP2 | CD109 | 0.70713 | 3 | 0 | 3 |
| TNFAIP2 | ITPA | 0.6968 | 3 | 0 | 3 |
| TNFAIP2 | MLX | 0.692658 | 3 | 0 | 3 |
| TNFAIP2 | SERPINB7 | 0.691684 | 3 | 0 | 3 |
| TNFAIP2 | TRAF3IP2 | 0.690675 | 4 | 0 | 4 |
| TNFAIP2 | ADORA2B | 0.673854 | 4 | 0 | 4 |
| TNFAIP2 | HAS3 | 0.641165 | 3 | 0 | 3 |
| TNFAIP2 | B4GALNT3 | 0.638269 | 4 | 0 | 3 |
| TNFAIP2 | NCOA7 | 0.637201 | 4 | 0 | 4 |
| TNFAIP2 | PPM1G | 0.636386 | 3 | 0 | 3 |
| TNFAIP2 | AP1B1 | 0.625628 | 3 | 0 | 3 |
| TNFAIP2 | ABCA13 | 0.623463 | 3 | 0 | 3 |
| TNFAIP2 | GALNT3 | 0.623409 | 3 | 0 | 3 |
| TNFAIP2 | TNFAIP1 | 0.618945 | 3 | 0 | 3 |
| TNFAIP2 | CPNE8 | 0.618816 | 3 | 0 | 3 |
| TNFAIP2 | DEPDC5 | 0.617445 | 5 | 0 | 5 |
| TNFAIP2 | FGFR3 | 0.617112 | 4 | 0 | 3 |
| TNFAIP2 | SREBF2 | 0.610907 | 4 | 0 | 4 |
| TNFAIP2 | GCLC | 0.610904 | 3 | 0 | 3 |
For details and further investigation, click here
