| Full name: CD207 molecule | Alias Symbol: Langerin|CLEC4K | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 50489 | HGNC ID: HGNC:17935 | Ensembl Gene: ENSG00000116031 | OMIM ID: 604862 |
| Drug and gene relationship at DGIdb | |||
Expression of CD207:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD207 | 50489 | 220428_at | -1.1333 | 0.1310 | |
| GSE20347 | CD207 | 50489 | 220428_at | -1.5049 | 0.0000 | |
| GSE23400 | CD207 | 50489 | 220428_at | -0.6523 | 0.0000 | |
| GSE26886 | CD207 | 50489 | 220428_at | -2.5272 | 0.0000 | |
| GSE29001 | CD207 | 50489 | 220428_at | -1.3826 | 0.0006 | |
| GSE38129 | CD207 | 50489 | 220428_at | -1.3208 | 0.0000 | |
| GSE45670 | CD207 | 50489 | 220428_at | -1.3282 | 0.0002 | |
| GSE53622 | CD207 | 50489 | 117358 | -2.5667 | 0.0000 | |
| GSE53624 | CD207 | 50489 | 117358 | -3.3699 | 0.0000 | |
| GSE63941 | CD207 | 50489 | 220428_at | 0.0928 | 0.5304 | |
| GSE77861 | CD207 | 50489 | 220428_at | -1.7946 | 0.0008 | |
| SRP007169 | CD207 | 50489 | RNAseq | -3.9621 | 0.0000 | |
| SRP064894 | CD207 | 50489 | RNAseq | -2.8769 | 0.0000 | |
| SRP133303 | CD207 | 50489 | RNAseq | -2.5184 | 0.0000 | |
| SRP159526 | CD207 | 50489 | RNAseq | -2.8842 | 0.0000 | |
| SRP219564 | CD207 | 50489 | RNAseq | -2.8541 | 0.0038 | |
| TCGA | CD207 | 50489 | RNAseq | 0.6405 | 0.1042 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by CD207 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD207:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD207 | 50489 | 11 | 1 | 18 | |
| GSE20123 | CD207 | 50489 | 11 | 1 | 18 | |
| GSE43470 | CD207 | 50489 | 3 | 0 | 40 | |
| GSE46452 | CD207 | 50489 | 2 | 3 | 54 | |
| GSE47630 | CD207 | 50489 | 7 | 0 | 33 | |
| GSE54993 | CD207 | 50489 | 0 | 6 | 64 | |
| GSE54994 | CD207 | 50489 | 11 | 0 | 42 | |
| GSE60625 | CD207 | 50489 | 0 | 3 | 8 | |
| GSE74703 | CD207 | 50489 | 3 | 0 | 33 | |
| GSE74704 | CD207 | 50489 | 9 | 0 | 11 | |
| TCGA | CD207 | 50489 | 37 | 2 | 57 |
Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.
Somatic mutations of CD207:
Generating mutation plots.
Highly correlated genes for CD207:
Showing top 20/1530 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD207 | CD1A | 0.874784 | 10 | 0 | 10 |
| CD207 | FCER1A | 0.817314 | 9 | 0 | 9 |
| CD207 | TMEM61 | 0.775607 | 3 | 0 | 3 |
| CD207 | HLA-DQB2 | 0.764467 | 9 | 0 | 8 |
| CD207 | SNORA68 | 0.751708 | 4 | 0 | 4 |
| CD207 | ASPG | 0.748179 | 6 | 0 | 6 |
| CD207 | C5orf66-AS1 | 0.745786 | 6 | 0 | 6 |
| CD207 | RBM20 | 0.744053 | 3 | 0 | 3 |
| CD207 | A2ML1 | 0.742578 | 7 | 0 | 7 |
| CD207 | KRT78 | 0.741852 | 7 | 0 | 7 |
| CD207 | BBOX1 | 0.741802 | 10 | 0 | 10 |
| CD207 | EHD3 | 0.741614 | 10 | 0 | 10 |
| CD207 | GYS2 | 0.737474 | 10 | 0 | 10 |
| CD207 | SAMD5 | 0.736474 | 6 | 0 | 6 |
| CD207 | SLURP1 | 0.734389 | 11 | 0 | 11 |
| CD207 | ALDH9A1 | 0.7337 | 10 | 0 | 10 |
| CD207 | MAPK3 | 0.732939 | 10 | 0 | 10 |
| CD207 | CYSRT1 | 0.731687 | 6 | 0 | 6 |
| CD207 | CTTNBP2 | 0.728283 | 6 | 0 | 6 |
| CD207 | NAGK | 0.726881 | 10 | 0 | 9 |
For details and further investigation, click here
