| Full name: retinol dehydrogenase 12 | Alias Symbol: FLJ30273|SDR7C2|LCA13|RP53 | ||
| Type: protein-coding gene | Cytoband: 14q24.1 | ||
| Entrez ID: 145226 | HGNC ID: HGNC:19977 | Ensembl Gene: ENSG00000139988 | OMIM ID: 608830 |
| Drug and gene relationship at DGIdb | |||
Expression of RDH12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RDH12 | 145226 | 242998_at | -2.0328 | 0.1684 | |
| GSE26886 | RDH12 | 145226 | 242998_at | -3.1701 | 0.0000 | |
| GSE45670 | RDH12 | 145226 | 242998_at | -0.1378 | 0.8231 | |
| GSE53622 | RDH12 | 145226 | 9671 | -2.4381 | 0.0000 | |
| GSE53624 | RDH12 | 145226 | 9671 | -3.0849 | 0.0000 | |
| GSE63941 | RDH12 | 145226 | 242998_at | 0.7407 | 0.0186 | |
| GSE77861 | RDH12 | 145226 | 242998_at | -1.0234 | 0.0311 | |
| GSE97050 | RDH12 | 145226 | A_23_P37088 | 0.2315 | 0.6699 | |
| SRP007169 | RDH12 | 145226 | RNAseq | -5.5681 | 0.0000 | |
| SRP008496 | RDH12 | 145226 | RNAseq | -3.1242 | 0.0005 | |
| SRP064894 | RDH12 | 145226 | RNAseq | -3.3340 | 0.0000 | |
| SRP133303 | RDH12 | 145226 | RNAseq | -2.9653 | 0.0000 | |
| SRP159526 | RDH12 | 145226 | RNAseq | -2.9082 | 0.0005 | |
| SRP193095 | RDH12 | 145226 | RNAseq | -3.7724 | 0.0000 | |
| TCGA | RDH12 | 145226 | RNAseq | -0.9728 | 0.0196 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by RDH12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RDH12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RDH12 | 145226 | 7 | 2 | 21 | |
| GSE20123 | RDH12 | 145226 | 7 | 2 | 21 | |
| GSE43470 | RDH12 | 145226 | 8 | 2 | 33 | |
| GSE46452 | RDH12 | 145226 | 16 | 3 | 40 | |
| GSE47630 | RDH12 | 145226 | 11 | 9 | 20 | |
| GSE54993 | RDH12 | 145226 | 3 | 9 | 58 | |
| GSE54994 | RDH12 | 145226 | 18 | 5 | 30 | |
| GSE60625 | RDH12 | 145226 | 0 | 2 | 9 | |
| GSE74703 | RDH12 | 145226 | 7 | 2 | 27 | |
| GSE74704 | RDH12 | 145226 | 3 | 2 | 15 | |
| TCGA | RDH12 | 145226 | 34 | 15 | 47 |
Total number of gains: 114; Total number of losses: 53; Total Number of normals: 321.
Somatic mutations of RDH12:
Generating mutation plots.
Highly correlated genes for RDH12:
Showing top 20/1157 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RDH12 | CYSRT1 | 0.784817 | 6 | 0 | 6 |
| RDH12 | PRSS27 | 0.777718 | 6 | 0 | 6 |
| RDH12 | RAET1E | 0.769728 | 6 | 0 | 6 |
| RDH12 | TGM1 | 0.765217 | 8 | 0 | 8 |
| RDH12 | KCNK7 | 0.761803 | 7 | 0 | 6 |
| RDH12 | ECM1 | 0.758217 | 6 | 0 | 6 |
| RDH12 | EMC3 | 0.757328 | 5 | 0 | 5 |
| RDH12 | MPZL3 | 0.753795 | 8 | 0 | 8 |
| RDH12 | DNASE1L3 | 0.749615 | 7 | 0 | 6 |
| RDH12 | IL18 | 0.74798 | 6 | 0 | 5 |
| RDH12 | CWH43 | 0.747846 | 6 | 0 | 5 |
| RDH12 | SH3PXD2A-AS1 | 0.746223 | 4 | 0 | 4 |
| RDH12 | SLC39A2 | 0.745751 | 8 | 0 | 7 |
| RDH12 | KRT78 | 0.745661 | 6 | 0 | 6 |
| RDH12 | GDPD3 | 0.744644 | 8 | 0 | 7 |
| RDH12 | IL22RA1 | 0.743241 | 6 | 0 | 6 |
| RDH12 | CRCT1 | 0.739486 | 8 | 0 | 7 |
| RDH12 | INO80C | 0.738705 | 6 | 0 | 6 |
| RDH12 | TMEM45B | 0.737722 | 9 | 0 | 7 |
| RDH12 | CEACAM7 | 0.737689 | 6 | 0 | 6 |
For details and further investigation, click here
