| Full name: poly(ADP-ribose) polymerase family member 15 | Alias Symbol: FLJ40597|pART7 | ||
| Type: protein-coding gene | Cytoband: 3q21.1 | ||
| Entrez ID: 165631 | HGNC ID: HGNC:26876 | Ensembl Gene: ENSG00000173200 | OMIM ID: 612066 |
| Drug and gene relationship at DGIdb | |||
Expression of PARP15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PARP15 | 165631 | 1564310_a_at | 0.5007 | 0.5030 | |
| GSE26886 | PARP15 | 165631 | 1564310_a_at | -0.1381 | 0.1596 | |
| GSE45670 | PARP15 | 165631 | 1564310_a_at | 0.0894 | 0.5010 | |
| GSE53622 | PARP15 | 165631 | 140146 | -0.6016 | 0.0019 | |
| GSE53624 | PARP15 | 165631 | 140146 | -0.9205 | 0.0000 | |
| GSE63941 | PARP15 | 165631 | 1564310_a_at | 0.0823 | 0.6303 | |
| GSE77861 | PARP15 | 165631 | 1564310_a_at | -0.1236 | 0.1411 | |
| GSE97050 | PARP15 | 165631 | A_33_P3316544 | 1.0161 | 0.1736 | |
| SRP007169 | PARP15 | 165631 | RNAseq | -0.5045 | 0.3891 | |
| SRP008496 | PARP15 | 165631 | RNAseq | 1.2685 | 0.0013 | |
| SRP064894 | PARP15 | 165631 | RNAseq | -1.3949 | 0.0000 | |
| SRP133303 | PARP15 | 165631 | RNAseq | -0.1080 | 0.5142 | |
| SRP159526 | PARP15 | 165631 | RNAseq | -1.1459 | 0.0104 | |
| SRP193095 | PARP15 | 165631 | RNAseq | 0.0197 | 0.9114 | |
| SRP219564 | PARP15 | 165631 | RNAseq | -0.6155 | 0.3330 | |
| TCGA | PARP15 | 165631 | RNAseq | -0.3422 | 0.2981 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by PARP15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PARP15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PARP15 | 165631 | 18 | 0 | 12 | |
| GSE20123 | PARP15 | 165631 | 18 | 0 | 12 | |
| GSE43470 | PARP15 | 165631 | 20 | 0 | 23 | |
| GSE46452 | PARP15 | 165631 | 14 | 5 | 40 | |
| GSE47630 | PARP15 | 165631 | 17 | 4 | 19 | |
| GSE54993 | PARP15 | 165631 | 2 | 6 | 62 | |
| GSE54994 | PARP15 | 165631 | 30 | 4 | 19 | |
| GSE60625 | PARP15 | 165631 | 0 | 6 | 5 | |
| GSE74703 | PARP15 | 165631 | 16 | 0 | 20 | |
| GSE74704 | PARP15 | 165631 | 13 | 0 | 7 | |
| TCGA | PARP15 | 165631 | 54 | 6 | 36 |
Total number of gains: 202; Total number of losses: 31; Total Number of normals: 255.
Somatic mutations of PARP15:
Generating mutation plots.
Highly correlated genes for PARP15:
Showing top 20/208 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PARP15 | APBB1IP | 0.789068 | 4 | 0 | 4 |
| PARP15 | NPRL2 | 0.756266 | 3 | 0 | 3 |
| PARP15 | UBASH3A | 0.737286 | 5 | 0 | 4 |
| PARP15 | INPP5D | 0.732188 | 5 | 0 | 5 |
| PARP15 | CD3E | 0.726019 | 6 | 0 | 5 |
| PARP15 | PLCB2 | 0.723974 | 4 | 0 | 4 |
| PARP15 | CD226 | 0.721869 | 4 | 0 | 4 |
| PARP15 | GIMAP5 | 0.717005 | 3 | 0 | 3 |
| PARP15 | GIMAP4 | 0.706266 | 3 | 0 | 3 |
| PARP15 | IRF4 | 0.703583 | 5 | 0 | 5 |
| PARP15 | GIMAP1 | 0.701303 | 3 | 0 | 3 |
| PARP15 | PARVG | 0.698699 | 5 | 0 | 4 |
| PARP15 | AOAH | 0.69062 | 3 | 0 | 3 |
| PARP15 | UBA7 | 0.689337 | 3 | 0 | 3 |
| PARP15 | ZAP70 | 0.68228 | 6 | 0 | 4 |
| PARP15 | GPR171 | 0.681235 | 5 | 0 | 4 |
| PARP15 | ARHGAP15 | 0.680867 | 4 | 0 | 3 |
| PARP15 | PIK3R6 | 0.680572 | 4 | 0 | 4 |
| PARP15 | CD3D | 0.679233 | 6 | 0 | 5 |
| PARP15 | POU2AF1 | 0.677366 | 3 | 0 | 3 |
For details and further investigation, click here
