| Full name: thioredoxin like 4A | Alias Symbol: U5-15kD|DIM1|HsT161|DIB1|SNRNP15 | ||
| Type: protein-coding gene | Cytoband: 18q23 | ||
| Entrez ID: 10907 | HGNC ID: HGNC:30551 | Ensembl Gene: ENSG00000141759 | OMIM ID: 611595 |
| Drug and gene relationship at DGIdb | |||
Expression of TXNL4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TXNL4A | 10907 | 202836_s_at | -0.0755 | 0.9038 | |
| GSE20347 | TXNL4A | 10907 | 202836_s_at | -0.1414 | 0.1816 | |
| GSE23400 | TXNL4A | 10907 | 202836_s_at | -0.1141 | 0.1474 | |
| GSE26886 | TXNL4A | 10907 | 202836_s_at | 0.0025 | 0.9899 | |
| GSE29001 | TXNL4A | 10907 | 202836_s_at | -0.4621 | 0.1550 | |
| GSE38129 | TXNL4A | 10907 | 202836_s_at | 0.0477 | 0.6672 | |
| GSE45670 | TXNL4A | 10907 | 202836_s_at | 0.0282 | 0.8449 | |
| GSE53622 | TXNL4A | 10907 | 65476 | -0.2503 | 0.0001 | |
| GSE53624 | TXNL4A | 10907 | 65476 | -0.1341 | 0.0711 | |
| GSE63941 | TXNL4A | 10907 | 202836_s_at | -0.5985 | 0.2710 | |
| GSE77861 | TXNL4A | 10907 | 202836_s_at | -0.0104 | 0.9800 | |
| GSE97050 | TXNL4A | 10907 | A_23_P130304 | 0.0590 | 0.8434 | |
| SRP007169 | TXNL4A | 10907 | RNAseq | -0.9242 | 0.0067 | |
| SRP008496 | TXNL4A | 10907 | RNAseq | -0.5485 | 0.0647 | |
| SRP064894 | TXNL4A | 10907 | RNAseq | 0.0097 | 0.9703 | |
| SRP133303 | TXNL4A | 10907 | RNAseq | 0.0335 | 0.8595 | |
| SRP159526 | TXNL4A | 10907 | RNAseq | 0.1807 | 0.6224 | |
| SRP193095 | TXNL4A | 10907 | RNAseq | -0.3217 | 0.0071 | |
| SRP219564 | TXNL4A | 10907 | RNAseq | -0.4346 | 0.2617 | |
| TCGA | TXNL4A | 10907 | RNAseq | -0.0191 | 0.7472 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TXNL4A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TXNL4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TXNL4A | 10907 | 1 | 12 | 17 | |
| GSE20123 | TXNL4A | 10907 | 1 | 12 | 17 | |
| GSE43470 | TXNL4A | 10907 | 0 | 12 | 31 | |
| GSE46452 | TXNL4A | 10907 | 1 | 26 | 32 | |
| GSE47630 | TXNL4A | 10907 | 5 | 22 | 13 | |
| GSE54993 | TXNL4A | 10907 | 9 | 0 | 61 | |
| GSE54994 | TXNL4A | 10907 | 1 | 19 | 33 | |
| GSE60625 | TXNL4A | 10907 | 0 | 4 | 7 | |
| GSE74703 | TXNL4A | 10907 | 0 | 8 | 28 | |
| GSE74704 | TXNL4A | 10907 | 0 | 9 | 11 | |
| TCGA | TXNL4A | 10907 | 7 | 45 | 44 |
Total number of gains: 25; Total number of losses: 169; Total Number of normals: 294.
Somatic mutations of TXNL4A:
Generating mutation plots.
Highly correlated genes for TXNL4A:
Showing top 20/219 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TXNL4A | MGAT4A | 0.765779 | 3 | 0 | 3 |
| TXNL4A | MRI1 | 0.742773 | 3 | 0 | 3 |
| TXNL4A | KDM4B | 0.740776 | 3 | 0 | 3 |
| TXNL4A | SF1 | 0.736249 | 4 | 0 | 4 |
| TXNL4A | SCML1 | 0.723856 | 3 | 0 | 3 |
| TXNL4A | TUFM | 0.718557 | 3 | 0 | 3 |
| TXNL4A | HERPUD1 | 0.717358 | 3 | 0 | 3 |
| TXNL4A | CD63 | 0.715628 | 3 | 0 | 3 |
| TXNL4A | DDX54 | 0.714098 | 3 | 0 | 3 |
| TXNL4A | ZNF740 | 0.699044 | 3 | 0 | 3 |
| TXNL4A | TNFAIP8L2 | 0.697969 | 3 | 0 | 3 |
| TXNL4A | RBL2 | 0.69579 | 3 | 0 | 3 |
| TXNL4A | ATP11C | 0.693438 | 4 | 0 | 3 |
| TXNL4A | ZFR | 0.689823 | 3 | 0 | 3 |
| TXNL4A | MLLT3 | 0.688524 | 3 | 0 | 3 |
| TXNL4A | COPS5 | 0.688041 | 4 | 0 | 4 |
| TXNL4A | NMT2 | 0.687587 | 3 | 0 | 3 |
| TXNL4A | TKT | 0.687132 | 3 | 0 | 3 |
| TXNL4A | VPS37C | 0.685933 | 3 | 0 | 3 |
| TXNL4A | NFATC1 | 0.680291 | 3 | 0 | 3 |
For details and further investigation, click here
