| Full name: CD69 molecule | Alias Symbol: CLEC2C | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 969 | HGNC ID: HGNC:1694 | Ensembl Gene: ENSG00000110848 | OMIM ID: 107273 |
| Drug and gene relationship at DGIdb | |||
Expression of CD69:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD69 | 969 | 209795_at | -0.2389 | 0.9243 | |
| GSE20347 | CD69 | 969 | 209795_at | -0.8972 | 0.0158 | |
| GSE23400 | CD69 | 969 | 209795_at | -0.1247 | 0.2985 | |
| GSE26886 | CD69 | 969 | 209795_at | -0.2966 | 0.7137 | |
| GSE29001 | CD69 | 969 | 209795_at | -0.3370 | 0.5860 | |
| GSE38129 | CD69 | 969 | 209795_at | -1.1166 | 0.0027 | |
| GSE45670 | CD69 | 969 | 209795_at | -1.4635 | 0.0014 | |
| GSE53622 | CD69 | 969 | 82816 | -0.2884 | 0.1274 | |
| GSE53624 | CD69 | 969 | 20266 | -0.8292 | 0.0000 | |
| GSE63941 | CD69 | 969 | 209795_at | -0.4140 | 0.0648 | |
| GSE77861 | CD69 | 969 | 209795_at | -0.0803 | 0.5576 | |
| GSE97050 | CD69 | 969 | A_33_P3241021 | 0.7814 | 0.1939 | |
| SRP007169 | CD69 | 969 | RNAseq | -0.5702 | 0.4127 | |
| SRP064894 | CD69 | 969 | RNAseq | -0.3679 | 0.2856 | |
| SRP133303 | CD69 | 969 | RNAseq | 0.1568 | 0.5807 | |
| SRP159526 | CD69 | 969 | RNAseq | -0.8697 | 0.3131 | |
| SRP193095 | CD69 | 969 | RNAseq | 0.6744 | 0.0395 | |
| SRP219564 | CD69 | 969 | RNAseq | 0.1513 | 0.7906 | |
| TCGA | CD69 | 969 | RNAseq | -0.0484 | 0.8305 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CD69 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD69:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD69 | 969 | 6 | 3 | 21 | |
| GSE20123 | CD69 | 969 | 6 | 3 | 21 | |
| GSE43470 | CD69 | 969 | 8 | 3 | 32 | |
| GSE46452 | CD69 | 969 | 10 | 1 | 48 | |
| GSE47630 | CD69 | 969 | 14 | 2 | 24 | |
| GSE54993 | CD69 | 969 | 1 | 10 | 59 | |
| GSE54994 | CD69 | 969 | 9 | 2 | 42 | |
| GSE60625 | CD69 | 969 | 0 | 1 | 10 | |
| GSE74703 | CD69 | 969 | 8 | 2 | 26 | |
| GSE74704 | CD69 | 969 | 4 | 2 | 14 | |
| TCGA | CD69 | 969 | 39 | 6 | 51 |
Total number of gains: 105; Total number of losses: 35; Total Number of normals: 348.
Somatic mutations of CD69:
Generating mutation plots.
Highly correlated genes for CD69:
Showing top 20/380 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD69 | ARHGAP15 | 0.746298 | 4 | 0 | 4 |
| CD69 | LY9 | 0.717001 | 3 | 0 | 3 |
| CD69 | ST8SIA4 | 0.716587 | 4 | 0 | 4 |
| CD69 | RNASE3 | 0.707948 | 3 | 0 | 3 |
| CD69 | IQCK | 0.697565 | 3 | 0 | 3 |
| CD69 | CYTIP | 0.69702 | 10 | 0 | 10 |
| CD69 | PCGF5 | 0.685697 | 6 | 0 | 6 |
| CD69 | GIMAP5 | 0.678486 | 4 | 0 | 3 |
| CD69 | ITK | 0.673136 | 11 | 0 | 10 |
| CD69 | TAGAP | 0.664587 | 6 | 0 | 5 |
| CD69 | GPR183 | 0.664183 | 12 | 0 | 10 |
| CD69 | ZCCHC2 | 0.662202 | 3 | 0 | 3 |
| CD69 | ARHGEF6 | 0.662076 | 12 | 0 | 11 |
| CD69 | C1orf162 | 0.66207 | 7 | 0 | 5 |
| CD69 | SRGN | 0.660204 | 12 | 0 | 10 |
| CD69 | GIMAP4 | 0.660055 | 11 | 0 | 10 |
| CD69 | GIMAP7 | 0.657355 | 7 | 0 | 6 |
| CD69 | EVI2B | 0.657302 | 12 | 0 | 11 |
| CD69 | MPEG1 | 0.652228 | 8 | 0 | 7 |
| CD69 | GAB3 | 0.650973 | 7 | 0 | 5 |
For details and further investigation, click here
