| Full name: serglycin | Alias Symbol: PPG | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 5552 | HGNC ID: HGNC:9361 | Ensembl Gene: ENSG00000122862 | OMIM ID: 177040 |
| Drug and gene relationship at DGIdb | |||
Expression of SRGN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SRGN | 5552 | 201859_at | -0.0190 | 0.9889 | |
| GSE20347 | SRGN | 5552 | 201859_at | 0.2940 | 0.3219 | |
| GSE23400 | SRGN | 5552 | 201859_at | 0.5728 | 0.0017 | |
| GSE26886 | SRGN | 5552 | 201859_at | 0.3307 | 0.5642 | |
| GSE29001 | SRGN | 5552 | 201859_at | 0.6395 | 0.0430 | |
| GSE38129 | SRGN | 5552 | 201859_at | 0.1043 | 0.7343 | |
| GSE45670 | SRGN | 5552 | 201859_at | -0.5018 | 0.2177 | |
| GSE53622 | SRGN | 5552 | 80752 | 0.4364 | 0.0042 | |
| GSE53624 | SRGN | 5552 | 80752 | 0.1774 | 0.3272 | |
| GSE63941 | SRGN | 5552 | 201859_at | -2.3733 | 0.2604 | |
| GSE77861 | SRGN | 5552 | 201859_at | 1.4102 | 0.0008 | |
| GSE97050 | SRGN | 5552 | A_23_P86653 | 0.7006 | 0.1267 | |
| SRP007169 | SRGN | 5552 | RNAseq | 1.4854 | 0.0114 | |
| SRP008496 | SRGN | 5552 | RNAseq | 1.3873 | 0.0001 | |
| SRP064894 | SRGN | 5552 | RNAseq | 0.7374 | 0.0438 | |
| SRP133303 | SRGN | 5552 | RNAseq | 0.9700 | 0.0001 | |
| SRP159526 | SRGN | 5552 | RNAseq | 0.2531 | 0.7645 | |
| SRP193095 | SRGN | 5552 | RNAseq | 1.1839 | 0.0000 | |
| SRP219564 | SRGN | 5552 | RNAseq | 1.0422 | 0.0470 | |
| TCGA | SRGN | 5552 | RNAseq | -0.1109 | 0.2818 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by SRGN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SRGN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SRGN | 5552 | 3 | 4 | 23 | |
| GSE20123 | SRGN | 5552 | 3 | 3 | 24 | |
| GSE43470 | SRGN | 5552 | 1 | 7 | 35 | |
| GSE46452 | SRGN | 5552 | 0 | 11 | 48 | |
| GSE47630 | SRGN | 5552 | 2 | 14 | 24 | |
| GSE54993 | SRGN | 5552 | 8 | 0 | 62 | |
| GSE54994 | SRGN | 5552 | 2 | 12 | 39 | |
| GSE60625 | SRGN | 5552 | 0 | 0 | 11 | |
| GSE74703 | SRGN | 5552 | 1 | 4 | 31 | |
| GSE74704 | SRGN | 5552 | 1 | 1 | 18 | |
| TCGA | SRGN | 5552 | 10 | 22 | 64 |
Total number of gains: 31; Total number of losses: 78; Total Number of normals: 379.
Somatic mutations of SRGN:
Generating mutation plots.
Highly correlated genes for SRGN:
Showing top 20/878 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SRGN | CD53 | 0.780648 | 10 | 0 | 10 |
| SRGN | C19orf38 | 0.768584 | 3 | 0 | 3 |
| SRGN | ARHGAP15 | 0.763601 | 3 | 0 | 3 |
| SRGN | FCER1G | 0.763135 | 11 | 0 | 11 |
| SRGN | LILRA6 | 0.761152 | 4 | 0 | 4 |
| SRGN | FCGR3A | 0.760965 | 3 | 0 | 3 |
| SRGN | PLEK | 0.75823 | 5 | 0 | 4 |
| SRGN | SAMSN1 | 0.757336 | 12 | 0 | 11 |
| SRGN | CD163 | 0.756016 | 12 | 0 | 12 |
| SRGN | COX7A2L | 0.752124 | 3 | 0 | 3 |
| SRGN | HLTF | 0.749572 | 3 | 0 | 3 |
| SRGN | C1QA | 0.748995 | 12 | 0 | 12 |
| SRGN | TYROBP | 0.747701 | 12 | 0 | 12 |
| SRGN | EVI2B | 0.747621 | 11 | 0 | 11 |
| SRGN | BRIX1 | 0.747558 | 3 | 0 | 3 |
| SRGN | AKR1B1 | 0.742637 | 3 | 0 | 3 |
| SRGN | TNFRSF1B | 0.741377 | 12 | 0 | 11 |
| SRGN | C1orf162 | 0.740519 | 8 | 0 | 8 |
| SRGN | LAPTM5 | 0.739857 | 12 | 0 | 11 |
| SRGN | TRAF3 | 0.739079 | 3 | 0 | 3 |
For details and further investigation, click here
