CD81

 

Full name: CD81 molecule Alias Symbol: TAPA-1|TSPAN28
Type: protein-coding gene Cytoband: 11p15.5
Entrez ID: 975 HGNC ID: HGNC:1701 Ensembl Gene: ENSG00000110651 OMIM ID: 186845
Drug and gene relationship at DGIdb

 

Expression of CD81:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CD81 975 200675_at 0.0792 0.9080
GSE20347 CD81 975 200675_at 0.7946 0.0001
GSE23400 CD81 975 200675_at 0.3413 0.0026
GSE26886 CD81 975 200675_at 0.6781 0.0067
GSE29001 CD81 975 200675_at 0.4436 0.3172
GSE38129 CD81 975 200675_at 0.3074 0.2679
GSE45670 CD81 975 200675_at -0.1694 0.4249
GSE53622 CD81 975 105637 0.0087 0.9295
GSE53624 CD81 975 105637 0.2449 0.0007
GSE63941 CD81 975 200675_at -1.4475 0.0010
GSE77861 CD81 975 200675_at 0.6915 0.0238
GSE97050 CD81 975 A_23_P13425 -0.2104 0.5824
SRP007169 CD81 975 RNAseq 0.9881 0.0189
SRP008496 CD81 975 RNAseq 0.8605 0.0017
SRP064894 CD81 975 RNAseq 0.6846 0.0680
SRP133303 CD81 975 RNAseq 0.1051 0.5480
SRP159526 CD81 975 RNAseq 0.1451 0.4040
SRP193095 CD81 975 RNAseq 0.6525 0.0000
SRP219564 CD81 975 RNAseq 0.1395 0.8439
TCGA CD81 975 RNAseq -0.0519 0.2444

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by CD81 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CD81:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CD81 975 1 11 18
GSE20123 CD81 975 1 12 17
GSE43470 CD81 975 1 9 33
GSE46452 CD81 975 7 8 44
GSE47630 CD81 975 4 12 24
GSE54993 CD81 975 3 1 66
GSE54994 CD81 975 1 12 40
GSE60625 CD81 975 0 0 11
GSE74703 CD81 975 1 7 28
GSE74704 CD81 975 0 8 12
TCGA CD81 975 8 39 49

Total number of gains: 27; Total number of losses: 119; Total Number of normals: 342.  

 

Somatic mutations of CD81:

 

Generating mutation plots.

 

Highly correlated genes for CD81:

 

Showing top 20/1035 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CD81MSANTD40.727628303
CD81TUBB0.715127303
CD81FKBP70.702546707
CD81YIF1A0.689635303
CD81DCHS10.687186808
CD81TSPAN180.685366606
CD81CNPY30.685016505
CD81DENND5A0.68096913011
CD81ANTXR20.6803806
CD81MAPRE20.678949909
CD81LBH0.67788212011
CD81PLEKHO10.67582612011
CD81RASSF80.672023807
CD81PCDH90.671413605
CD81C19orf120.671227303
CD81CD99L20.670354706
CD81KCNJ80.6675351009
CD81C19orf530.667422303
CD81MRPS120.666014503
CD81BICC10.664559908

For details and further investigation, click here