| Full name: CDC42 binding protein kinase beta | Alias Symbol: MRCKB|KIAA1124 | ||
| Type: protein-coding gene | Cytoband: 14q32.32 | ||
| Entrez ID: 9578 | HGNC ID: HGNC:1738 | Ensembl Gene: ENSG00000198752 | OMIM ID: 614062 |
| Drug and gene relationship at DGIdb | |||
Expression of CDC42BPB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC42BPB | 9578 | 217849_s_at | 0.1939 | 0.5683 | |
| GSE20347 | CDC42BPB | 9578 | 217849_s_at | 0.1094 | 0.5767 | |
| GSE23400 | CDC42BPB | 9578 | 217849_s_at | 0.2178 | 0.0490 | |
| GSE26886 | CDC42BPB | 9578 | 1557963_at | -1.8469 | 0.0000 | |
| GSE29001 | CDC42BPB | 9578 | 217849_s_at | 0.1149 | 0.7429 | |
| GSE38129 | CDC42BPB | 9578 | 217849_s_at | 0.0048 | 0.9825 | |
| GSE45670 | CDC42BPB | 9578 | 217849_s_at | 0.2193 | 0.1086 | |
| GSE63941 | CDC42BPB | 9578 | 217849_s_at | -0.1857 | 0.6439 | |
| GSE77861 | CDC42BPB | 9578 | 217849_s_at | 0.1708 | 0.7422 | |
| GSE97050 | CDC42BPB | 9578 | A_23_P380766 | -0.1413 | 0.5396 | |
| SRP007169 | CDC42BPB | 9578 | RNAseq | 1.1689 | 0.0143 | |
| SRP008496 | CDC42BPB | 9578 | RNAseq | 1.1189 | 0.0011 | |
| SRP064894 | CDC42BPB | 9578 | RNAseq | -0.1160 | 0.5194 | |
| SRP133303 | CDC42BPB | 9578 | RNAseq | 0.1825 | 0.3033 | |
| SRP159526 | CDC42BPB | 9578 | RNAseq | 0.0830 | 0.8082 | |
| SRP193095 | CDC42BPB | 9578 | RNAseq | 0.2103 | 0.0497 | |
| SRP219564 | CDC42BPB | 9578 | RNAseq | -0.1251 | 0.5954 | |
| TCGA | CDC42BPB | 9578 | RNAseq | -0.1057 | 0.0235 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by CDC42BPB expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CDC42BPB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC42BPB | 9578 | 12 | 4 | 14 | |
| GSE20123 | CDC42BPB | 9578 | 11 | 3 | 16 | |
| GSE43470 | CDC42BPB | 9578 | 6 | 4 | 33 | |
| GSE46452 | CDC42BPB | 9578 | 18 | 4 | 37 | |
| GSE47630 | CDC42BPB | 9578 | 10 | 9 | 21 | |
| GSE54993 | CDC42BPB | 9578 | 3 | 8 | 59 | |
| GSE54994 | CDC42BPB | 9578 | 21 | 4 | 28 | |
| GSE60625 | CDC42BPB | 9578 | 0 | 2 | 9 | |
| GSE74703 | CDC42BPB | 9578 | 5 | 3 | 28 | |
| GSE74704 | CDC42BPB | 9578 | 5 | 3 | 12 | |
| TCGA | CDC42BPB | 9578 | 31 | 21 | 44 |
Total number of gains: 122; Total number of losses: 65; Total Number of normals: 301.
Somatic mutations of CDC42BPB:
Generating mutation plots.
Highly correlated genes for CDC42BPB:
Showing top 20/62 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC42BPB | RGS12 | 0.811311 | 4 | 0 | 4 |
| CDC42BPB | SFTPC | 0.74355 | 3 | 0 | 3 |
| CDC42BPB | CNOT3 | 0.728205 | 3 | 0 | 3 |
| CDC42BPB | BUD13 | 0.71715 | 3 | 0 | 3 |
| CDC42BPB | KCP | 0.712138 | 3 | 0 | 3 |
| CDC42BPB | DGAT2 | 0.703227 | 3 | 0 | 3 |
| CDC42BPB | ZNF692 | 0.702774 | 4 | 0 | 4 |
| CDC42BPB | ABCA7 | 0.702675 | 3 | 0 | 3 |
| CDC42BPB | LRFN4 | 0.680842 | 3 | 0 | 3 |
| CDC42BPB | CSMD2 | 0.675532 | 3 | 0 | 3 |
| CDC42BPB | KIFC2 | 0.666598 | 3 | 0 | 3 |
| CDC42BPB | CC2D1B | 0.655039 | 4 | 0 | 3 |
| CDC42BPB | RBM25 | 0.652507 | 4 | 0 | 4 |
| CDC42BPB | CUL9 | 0.646117 | 3 | 0 | 3 |
| CDC42BPB | ARL4D | 0.645812 | 4 | 0 | 3 |
| CDC42BPB | FANK1 | 0.644815 | 4 | 0 | 4 |
| CDC42BPB | IPO13 | 0.643408 | 5 | 0 | 4 |
| CDC42BPB | RNF123 | 0.642248 | 5 | 0 | 4 |
| CDC42BPB | RRP1 | 0.640377 | 4 | 0 | 3 |
| CDC42BPB | RUSC1 | 0.640154 | 5 | 0 | 4 |
For details and further investigation, click here
