| Full name: CUB and Sushi multiple domains 2 | Alias Symbol: KIAA1884 | ||
| Type: protein-coding gene | Cytoband: 1p35.1 | ||
| Entrez ID: 114784 | HGNC ID: HGNC:19290 | Ensembl Gene: ENSG00000121904 | OMIM ID: 608398 |
| Drug and gene relationship at DGIdb | |||
Expression of CSMD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CSMD2 | 114784 | 233145_at | 0.0992 | 0.7473 | |
| GSE26886 | CSMD2 | 114784 | 1570169_at | -0.3679 | 0.0020 | |
| GSE45670 | CSMD2 | 114784 | 1570169_at | 0.0605 | 0.5091 | |
| GSE53622 | CSMD2 | 114784 | 69577 | 1.2741 | 0.0000 | |
| GSE53624 | CSMD2 | 114784 | 69577 | 0.1592 | 0.3304 | |
| GSE63941 | CSMD2 | 114784 | 1557143_at | -0.7020 | 0.0033 | |
| GSE77861 | CSMD2 | 114784 | 233145_at | -0.1713 | 0.1501 | |
| GSE97050 | CSMD2 | 114784 | A_33_P3246935 | 0.6152 | 0.1255 | |
| SRP007169 | CSMD2 | 114784 | RNAseq | 5.0519 | 0.0002 | |
| SRP133303 | CSMD2 | 114784 | RNAseq | 3.8919 | 0.0000 | |
| SRP159526 | CSMD2 | 114784 | RNAseq | 1.7996 | 0.0000 | |
| SRP193095 | CSMD2 | 114784 | RNAseq | 1.9637 | 0.0000 | |
| SRP219564 | CSMD2 | 114784 | RNAseq | 2.7458 | 0.0000 | |
| TCGA | CSMD2 | 114784 | RNAseq | 0.8324 | 0.0128 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by CSMD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CSMD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CSMD2 | 114784 | 2 | 5 | 23 | |
| GSE20123 | CSMD2 | 114784 | 2 | 4 | 24 | |
| GSE43470 | CSMD2 | 114784 | 5 | 6 | 32 | |
| GSE46452 | CSMD2 | 114784 | 4 | 1 | 54 | |
| GSE47630 | CSMD2 | 114784 | 8 | 3 | 29 | |
| GSE54993 | CSMD2 | 114784 | 1 | 1 | 68 | |
| GSE54994 | CSMD2 | 114784 | 11 | 2 | 40 | |
| GSE60625 | CSMD2 | 114784 | 0 | 0 | 11 | |
| GSE74703 | CSMD2 | 114784 | 4 | 4 | 28 | |
| GSE74704 | CSMD2 | 114784 | 1 | 0 | 19 | |
| TCGA | CSMD2 | 114784 | 13 | 18 | 65 |
Total number of gains: 51; Total number of losses: 44; Total Number of normals: 393.
Somatic mutations of CSMD2:
Generating mutation plots.
Highly correlated genes for CSMD2:
Showing top 20/96 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CSMD2 | P4HA3 | 0.761421 | 4 | 0 | 4 |
| CSMD2 | HAGHL | 0.752829 | 3 | 0 | 3 |
| CSMD2 | ACAN | 0.72179 | 3 | 0 | 3 |
| CSMD2 | DAB1 | 0.713165 | 4 | 0 | 4 |
| CSMD2 | GPHA2 | 0.705953 | 3 | 0 | 3 |
| CSMD2 | HAPLN3 | 0.705818 | 3 | 0 | 3 |
| CSMD2 | TMEM26 | 0.705649 | 4 | 0 | 4 |
| CSMD2 | ZNF575 | 0.705128 | 3 | 0 | 3 |
| CSMD2 | SERPINA10 | 0.703735 | 3 | 0 | 3 |
| CSMD2 | SYT3 | 0.700617 | 3 | 0 | 3 |
| CSMD2 | LDHAL6A | 0.685787 | 4 | 0 | 3 |
| CSMD2 | NLRP5 | 0.684191 | 3 | 0 | 3 |
| CSMD2 | SH2D5 | 0.682189 | 3 | 0 | 3 |
| CSMD2 | THBS2 | 0.681587 | 4 | 0 | 3 |
| CSMD2 | SLC25A18 | 0.680162 | 3 | 0 | 3 |
| CSMD2 | FANK1 | 0.677806 | 3 | 0 | 3 |
| CSMD2 | CDC42BPB | 0.675532 | 3 | 0 | 3 |
| CSMD2 | EPHB2 | 0.671289 | 3 | 0 | 3 |
| CSMD2 | ZCCHC18 | 0.671058 | 3 | 0 | 3 |
| CSMD2 | DPEP1 | 0.664262 | 3 | 0 | 3 |
For details and further investigation, click here
