| Full name: ankyrin repeat domain 54 | Alias Symbol: LIAR | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 129138 | HGNC ID: HGNC:25185 | Ensembl Gene: ENSG00000100124 | OMIM ID: 613383 |
| Drug and gene relationship at DGIdb | |||
Expression of ANKRD54:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD54 | 129138 | 231847_at | 0.3011 | 0.1458 | |
| GSE26886 | ANKRD54 | 129138 | 231847_at | 0.3705 | 0.0317 | |
| GSE45670 | ANKRD54 | 129138 | 231847_at | 0.2333 | 0.0152 | |
| GSE53622 | ANKRD54 | 129138 | 150804 | 0.0908 | 0.0769 | |
| GSE53624 | ANKRD54 | 129138 | 150804 | -0.2126 | 0.0010 | |
| GSE63941 | ANKRD54 | 129138 | 231847_at | -0.0352 | 0.9351 | |
| GSE77861 | ANKRD54 | 129138 | 231847_at | -0.0173 | 0.9102 | |
| GSE97050 | ANKRD54 | 129138 | A_33_P3237125 | 0.1637 | 0.5295 | |
| SRP007169 | ANKRD54 | 129138 | RNAseq | -0.7546 | 0.0433 | |
| SRP008496 | ANKRD54 | 129138 | RNAseq | -0.6368 | 0.0063 | |
| SRP064894 | ANKRD54 | 129138 | RNAseq | 0.5018 | 0.0250 | |
| SRP133303 | ANKRD54 | 129138 | RNAseq | 0.1034 | 0.4583 | |
| SRP159526 | ANKRD54 | 129138 | RNAseq | 0.5088 | 0.0214 | |
| SRP193095 | ANKRD54 | 129138 | RNAseq | 0.0171 | 0.8648 | |
| SRP219564 | ANKRD54 | 129138 | RNAseq | 0.1584 | 0.6646 | |
| TCGA | ANKRD54 | 129138 | RNAseq | 0.0573 | 0.3173 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKRD54 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD54:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD54 | 129138 | 6 | 5 | 19 | |
| GSE20123 | ANKRD54 | 129138 | 6 | 4 | 20 | |
| GSE43470 | ANKRD54 | 129138 | 4 | 6 | 33 | |
| GSE46452 | ANKRD54 | 129138 | 32 | 2 | 25 | |
| GSE47630 | ANKRD54 | 129138 | 9 | 4 | 27 | |
| GSE54993 | ANKRD54 | 129138 | 3 | 6 | 61 | |
| GSE54994 | ANKRD54 | 129138 | 9 | 8 | 36 | |
| GSE60625 | ANKRD54 | 129138 | 5 | 0 | 6 | |
| GSE74703 | ANKRD54 | 129138 | 4 | 4 | 28 | |
| GSE74704 | ANKRD54 | 129138 | 3 | 2 | 15 | |
| TCGA | ANKRD54 | 129138 | 27 | 15 | 54 |
Total number of gains: 108; Total number of losses: 56; Total Number of normals: 324.
Somatic mutations of ANKRD54:
Generating mutation plots.
Highly correlated genes for ANKRD54:
Showing top 20/408 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD54 | ROMO1 | 0.821277 | 3 | 0 | 3 |
| ANKRD54 | ERI3 | 0.814141 | 3 | 0 | 3 |
| ANKRD54 | SEC61A1 | 0.805911 | 3 | 0 | 3 |
| ANKRD54 | PLAGL2 | 0.797526 | 3 | 0 | 3 |
| ANKRD54 | UHMK1 | 0.790002 | 3 | 0 | 3 |
| ANKRD54 | DPM2 | 0.781417 | 3 | 0 | 3 |
| ANKRD54 | LSM1 | 0.780707 | 3 | 0 | 3 |
| ANKRD54 | CRTC2 | 0.772126 | 3 | 0 | 3 |
| ANKRD54 | TNK1 | 0.767567 | 3 | 0 | 3 |
| ANKRD54 | SCAF4 | 0.766593 | 3 | 0 | 3 |
| ANKRD54 | ERGIC3 | 0.759438 | 3 | 0 | 3 |
| ANKRD54 | RAB7A | 0.757606 | 3 | 0 | 3 |
| ANKRD54 | TSFM | 0.757062 | 3 | 0 | 3 |
| ANKRD54 | CSTF2T | 0.749806 | 3 | 0 | 3 |
| ANKRD54 | MMP15 | 0.748641 | 3 | 0 | 3 |
| ANKRD54 | AIMP2 | 0.746892 | 3 | 0 | 3 |
| ANKRD54 | SNRPD2 | 0.742945 | 3 | 0 | 3 |
| ANKRD54 | PIF1 | 0.741556 | 3 | 0 | 3 |
| ANKRD54 | CDC25A | 0.738405 | 3 | 0 | 3 |
| ANKRD54 | DNAJC2 | 0.73789 | 3 | 0 | 3 |
For details and further investigation, click here
