| Full name: pseudouridine synthase like 1 | Alias Symbol: FLJ90811 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 126789 | HGNC ID: HGNC:26914 | Ensembl Gene: ENSG00000169972 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PUSL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PUSL1 | 126789 | 228733_at | 0.3532 | 0.5649 | |
| GSE26886 | PUSL1 | 126789 | 228733_at | 0.1665 | 0.5395 | |
| GSE45670 | PUSL1 | 126789 | 228733_at | -0.1375 | 0.5240 | |
| GSE53622 | PUSL1 | 126789 | 27398 | -0.3420 | 0.0067 | |
| GSE53624 | PUSL1 | 126789 | 27398 | -0.3708 | 0.0000 | |
| GSE63941 | PUSL1 | 126789 | 228733_at | 0.1722 | 0.6816 | |
| GSE77861 | PUSL1 | 126789 | 228733_at | -0.3828 | 0.0467 | |
| GSE97050 | PUSL1 | 126789 | A_23_P51884 | 0.0413 | 0.9323 | |
| SRP007169 | PUSL1 | 126789 | RNAseq | -2.7510 | 0.0000 | |
| SRP008496 | PUSL1 | 126789 | RNAseq | -2.2593 | 0.0000 | |
| SRP064894 | PUSL1 | 126789 | RNAseq | -0.1999 | 0.5095 | |
| SRP133303 | PUSL1 | 126789 | RNAseq | -0.3738 | 0.0903 | |
| SRP159526 | PUSL1 | 126789 | RNAseq | -0.6830 | 0.0378 | |
| SRP193095 | PUSL1 | 126789 | RNAseq | -0.4083 | 0.0116 | |
| SRP219564 | PUSL1 | 126789 | RNAseq | -0.7360 | 0.0948 | |
| TCGA | PUSL1 | 126789 | RNAseq | 0.1720 | 0.0285 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PUSL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PUSL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PUSL1 | 126789 | 3 | 7 | 20 | |
| GSE20123 | PUSL1 | 126789 | 3 | 6 | 21 | |
| GSE43470 | PUSL1 | 126789 | 3 | 5 | 35 | |
| GSE46452 | PUSL1 | 126789 | 7 | 1 | 51 | |
| GSE47630 | PUSL1 | 126789 | 8 | 4 | 28 | |
| GSE54993 | PUSL1 | 126789 | 2 | 2 | 66 | |
| GSE54994 | PUSL1 | 126789 | 15 | 2 | 36 | |
| GSE60625 | PUSL1 | 126789 | 0 | 0 | 11 | |
| GSE74703 | PUSL1 | 126789 | 3 | 3 | 30 | |
| GSE74704 | PUSL1 | 126789 | 3 | 0 | 17 | |
| TCGA | PUSL1 | 126789 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of PUSL1:
Generating mutation plots.
Highly correlated genes for PUSL1:
Showing top 20/629 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PUSL1 | E2F8 | 0.81842 | 3 | 0 | 3 |
| PUSL1 | TBC1D22A | 0.78044 | 3 | 0 | 3 |
| PUSL1 | STX6 | 0.771178 | 3 | 0 | 3 |
| PUSL1 | SRPK1 | 0.765179 | 3 | 0 | 3 |
| PUSL1 | GTF2IRD1 | 0.756464 | 3 | 0 | 3 |
| PUSL1 | CDC42EP1 | 0.753019 | 3 | 0 | 3 |
| PUSL1 | SLC25A10 | 0.747883 | 3 | 0 | 3 |
| PUSL1 | ATP6V1A | 0.744317 | 3 | 0 | 3 |
| PUSL1 | PLK3 | 0.743302 | 3 | 0 | 3 |
| PUSL1 | TRIAP1 | 0.734845 | 3 | 0 | 3 |
| PUSL1 | POLR2A | 0.729571 | 3 | 0 | 3 |
| PUSL1 | RRP36 | 0.719929 | 3 | 0 | 3 |
| PUSL1 | MMAA | 0.717633 | 3 | 0 | 3 |
| PUSL1 | NECAP2 | 0.714149 | 4 | 0 | 4 |
| PUSL1 | AP1S3 | 0.713788 | 3 | 0 | 3 |
| PUSL1 | UXT | 0.707006 | 3 | 0 | 3 |
| PUSL1 | PDLIM2 | 0.706996 | 3 | 0 | 3 |
| PUSL1 | PTBP3 | 0.703022 | 4 | 0 | 4 |
| PUSL1 | ADAM11 | 0.702844 | 3 | 0 | 3 |
| PUSL1 | PRKCH | 0.701669 | 6 | 0 | 6 |
For details and further investigation, click here
